Search Results - "Nutt, E M"

Comparison of the in vivo anticoagulant properties of standard heparin and the highly selective factor Xa inhibitors antistasin and tick anticoagulant peptide (TAP) in a rabbit model of venous thrombosis by Vlasuk, G P, Ramjit, D, Fujita, T, Dunwiddie, C T, Nutt, E M, Smith, D E, Shebuski, R J

“…An in vivo thromboplastin (TP)-induced venous stasis thrombosis model in rabbits was used to compare the efficacy of standard heparin with the selective factor…”
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Chemical Synthesis and Enzymatic Activity of a 99-Residue Peptide with a Sequence Proposed for the Human Immunodeficiency Virus Protease by Nutt, Ruth F., Brady, Stephen F., Darke, Paul L., Ciccarone, Terrence M., Colton, C. Dylion, Nutt, Elka M., Rodkey, John A., Bennett, Carl D., Waxman, Lloyd H., Sigal, Irving S., Anderson, Paul S., Veber, Daniel F.

“…Retroviral proteins, including those from the human immunodeficiency virus (HIV), are synthesized as polyprotein precursors that require proteolytic cleavage…”
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Site-directed mutagenesis of the leech-derived factor Xa inhibitor antistasin : probing of the reactive site by HOFMANN, K. J, NUTT, E. M, DUNWIDDIE, C. T

“…Antistasin (ATS) is a leech-derived 119-amino-acid protein which exhibits potent and highly selective inhibition of coagulation Factor Xa. It inhibits Factor…”
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Cellular localization of activated factor X by Xa-specific probes by Zacharski, L R, Dunwiddie, C, Nutt, E M, Hunt, J, Memoli, V A

“…A probe, recombinant antistasin, that reacts specifically with the activated form of factor X (Xa) was used in immunohistochemical procedures to detect…”
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Maintenance of canine coronary artery patency following thrombolysis with front loaded plus low dose maintenance conjunctive therapy. A comparison of factor Xa versus thrombin inhibition by Lynch, Jr, J J, Sitko, G R, Mellott, M J, Nutt, E M, Lehman, E D, Friedman, P A, Dunwiddie, C T, Vlasuk, G P

“…The aim was to examine the abilities of the direct thrombin inhibitor, recombinant hirudin (rHIR), and the coagulation factor Xa inhibitor, recombinant tick…”
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Anticoagulant efficacy and immunogenicity of the selective factor Xa inhibitor antistasin following subcutaneous administration in the rhesus monkey by Dunwiddie, C T, Nutt, E M, Vlasuk, G P, Siegl, P K, Schaffer, L W

“…The antithrombotic efficacy and duration of action of a single subcutaneous administration of the selective factor Xa inhibitor recombinant antistasin (rATS)…”
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Reactivity of guinea-pig isolated trachea to methacholine, histamine and isoproterenol applied serosally versus mucosally by Fedan, J S, Nutt, M E, Frazer, D G

“…Guinea-pig tracheas were perfused with recirculating modified Krebs-Henseleit solution while monitoring changes in inflow-outflow pressure difference, which is…”
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Anticoagulant effects of the selective factor XA inhibitors tick anticoagulant peptide and antistasin in the APTT assay are determined by the relative rate of prothrombinase inhibition by Dunwiddie, C T, Smith, D E, Nutt, E M, Vlasuk, G P

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Site-directed analysis of the functional domains in the factor Xa inhibitor tick anticoagulant peptide: identification of two distinct regions that constitute the enzyme recognition sites by Dunwiddie, Christopher T, Neeper, Michael P, Nutt, Elka M, Waxman, Lloyd, Smith, Donna E, Hofmann, Kathryn J, Lumma, Patricia K, Garsky, Victor M, Vlasuk, George P

“…Recombinant tick anticoagulant peptide (rTAP) is a highly selective inhibitor of blood coagulation factor Xa. rTAP has been characterized kinetically as a…”
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Purification and characterization of recombinant antistasin: a leech-derived inhibitor of coagulation factor Xa by Nutt, E M, Jain, D, Lenny, A B, Schaffer, L, Siegl, P K, Dunwiddie, C T

“…Antistasin (ATS) is a selective, tight-binding inhibitor of blood coagulation Factor Xa originally isolated from the salivary glands of the Mexican leech…”
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Comparison of binding to rapidly activating delayed rectifier K+ channel, IKr, and effects on myocardial refractoriness for class III antiarrhythmic agents by Lynch, Jr, J J, Baskin, E P, Nutt, E M, Guinosso, Jr, P J, Hamill, T, Salata, J J, Woods, C M

“…Saturation binding studies in guinea pig ventricular myocytes with 3H-dofetilide, a radioligand for the cardiac rapidly activating delayed rectifier K+ IKr…”
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The hydrolysis and resynthesis of a single reactive site peptide bond in recombinant antistasin by coagulation factor Xa by Dunwiddie, C T, Vlasuk, G P, Nutt, E M

“…Antistasin (ATS) is a 119-amino acid, leech-derived protein which exhibits selective, tight-binding inhibition of blood coagulation factor Xa. Prolonged…”
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Effects of pituitrin and exercise on a water diuresis by BARCLAY, J A, KENNEY, R A, NUTT, M E

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The Biology of Blood by NUTT, M. E

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Some Aspects of Hæmatology by NUTT, M. E

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Pathways of coagulation activation in situ in rheumatoid synovial tissue by Zacharski, L R, Brown, F E, Memoli, V A, Kisiel, W, Kudryk, B J, Rousseau, S M, Hunt, J A, Dunwiddie, C, Nutt, E M

“…Immunohistochemical techniques were applied to rheumatoid synovium in order to detect components of coagulation and fibrinolysis pathways within these tissues…”
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An instrument for accurate reading of an improved Meyerstein haematocrit tube by GILDING, H P, MEYERSTEIN, W, NUTT, M E

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The alphavbeta3 integrin regulates alpha5beta1-mediated cell migration toward fibronectin by Simon, K O, Nutt, E M, Abraham, D G, Rodan, G A, Duong, L T

“…This study examines the interactions of alphavbeta3 and alpha5beta1 in the regulation of cell migration. Human embryonic kidney (HEK) 293 cells that express…”
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Bone‐marrow blood flow and cardiac output in the rabbit by Cumming, J. D., Nutt, Marjorie E.

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Intercellular plasma and its effect on absolute red cell volume determination by Jackson, D. Mary, Nutt, Marjorie E.

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