Search Results - "Nutt, David J"

Trial of Psilocybin versus Escitalopram for Depression by Carhart-Harris, Robin, Giribaldi, Bruna, Watts, Rosalind, Baker-Jones, Michelle, Murphy-Beiner, Ashleigh, Murphy, Roberta, Martell, Jonny, Blemings, Allan, Erritzoe, David, Nutt, David J

“…In a randomized trial involving 59 selected patients with depression, the change in depression scale scores from baseline to week 6 did not differ…”
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Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression by Roseman, Leor, Nutt, David J, Carhart-Harris, Robin L

“…It is a basic principle of the "psychedelic" treatment model that the quality of the acute experience mediates long-term improvements in mental health. In the…”
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Drug harms in the UK: a multicriteria decision analysis by Nutt, David J, Prof, King, Leslie A, PhD, Phillips, Lawrence D, PhD

“…Summary Background Proper assessment of the harms caused by the misuse of drugs can inform policy makers in health, policing, and social care. We aimed to…”
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Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution by Tagliazucchi, Enzo, Roseman, Leor, Kaelen, Mendel, Orban, Csaba, Muthukumaraswamy, Suresh D., Murphy, Kevin, Laufs, Helmut, Leech, Robert, McGonigle, John, Crossley, Nicolas, Bullmore, Edward, Williams, Tim, Bolstridge, Mark, Feilding, Amanda, Nutt, David J., Carhart-Harris, Robin

“…Lysergic acid diethylamide (LSD) is a non-selective serotonin-receptor agonist that was first synthesized in 1938 and identified as (potently) psychoactive in…”
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The dopamine theory of addiction: 40 years of highs and lows by Nutt, David J., Lingford-Hughes, Anne, Erritzoe, David, Stokes, Paul R. A.

“…In this Opinion article, Nutt and colleagues examine the history of and current evidence for the dopamine theory of addiction. They argue that dopamine's role…”
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Amphetamine, past and present – a pharmacological and clinical perspective by Heal, David J, Smith, Sharon L, Gosden, Jane, Nutt, David J

“…Amphetamine was discovered over 100 years ago. Since then, it has transformed from a drug that was freely available without prescription as a panacea for a…”
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Neural correlates of the LSD experience revealed by multimodal neuroimaging by Carhart-Harris, Robin L., Muthukumaraswamy, Suresh, Roseman, Leor, Kaelen, Mendel, Droog, Wouter, Murphy, Kevin, Tagliazucchi, Enzo, Schenberg, Eduardo E., Nest, Timothy, Orban, Csaba, Leech, Robert, Williams, Luke T., Williams, Tim M., Bolstridge, Mark, Sessa, Ben, McGonigle, John, Sereno, Martin I., Nichols, David, Hellyer, Peter J., Hobden, Peter, Evans, John, Singh, Krish D., Wise, Richard G., Curran, H. Valerie, Feilding, Amanda, Nutt, David J.

“…Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the human brain have never been studied before with modern…”
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Self-blinding citizen science to explore psychedelic microdosing by Szigeti, Balázs, Kartner, Laura, Blemings, Allan, Rosas, Fernando, Feilding, Amanda, Nutt, David J, Carhart-Harris, Robin L, Erritzoe, David

“…Microdosing is the practice of regularly using low doses of psychedelic drugs. Anecdotal reports suggest that microdosing enhances well-being and cognition;…”
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Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study by Carhart-Harris, Robin L, Dr, Bolstridge, Mark, MD, Rucker, James, MD, Day, Camilla M J, MD, Erritzoe, David, MD, Kaelen, Mendel, BSc, Bloomfield, Michael, MD, Rickard, James A, PhD, Forbes, Ben, Prof, Feilding, Amanda, Taylor, David, Prof, Pilling, Steve, Prof, Curran, Valerie H, Prof, Nutt, David J, Prof

“…Summary Background Psilocybin is a serotonin receptor agonist that occurs naturally in some mushroom species. Recent studies have assessed the therapeutic…”
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GABA system dysfunction in autism and related disorders: From synapse to symptoms by COGHLAN, Suzanne, HORDER, Jamie, INKSTER, Becky, ANDREINA MENDEZ, M, MURPHY, Declan G, NUTT, David J

“…Autism spectrum disorders (ASDs) are neurodevelopmental syndromes characterised by repetitive behaviours and restricted interests, impairments in social…”
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Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin by Carhart-Harris, Robin L, Erritzoe, David, Williams, Tim, Stone, James M, Reed, Laurence J, Colasanti, Alessandro, Tyacke, Robin J, Leech, Robert, Malizia, Andrea L, Murphy, Kevin, Hobden, Peter, Evans, John, Feilding, Amanda, Wise, Richard G, Nutt, David J

“…Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very…”
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GABA-A receptor differences in schizophrenia: a positron emission tomography study using [11C]Ro154513 by Marques, Tiago Reis, Ashok, Abhishekh H., Angelescu, Ilinca, Borgan, Faith, Myers, Jim, Lingford-Hughes, Anne, Nutt, David J., Veronese, Mattia, Turkheimer, Federico E., Howes, Oliver D.

“…A loss of GABA signaling is a prevailing hypothesis for the pathogenesis of schizophrenia. Preclinical studies indicate that blockade of the α5 subtype of the…”
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Imidazoline-I2 PET Tracers in Neuroimaging by Parker, Christine A, Nutt, David J, Tyacke, Robin J

“…Targeting neuroinflammation, and in particular, microglial activation and astrocytosis, is a current area of the focus of new treatment interventions for a…”
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Receptor-informed network control theory links LSD and psilocybin to a flattening of the brain’s control energy landscape by Singleton, S. Parker, Luppi, Andrea I., Carhart-Harris, Robin L., Cruzat, Josephine, Roseman, Leor, Nutt, David J., Deco, Gustavo, Kringelbach, Morten L., Stamatakis, Emmanuel A., Kuceyeski, Amy

“…Psychedelics including lysergic acid diethylamide (LSD) and psilocybin temporarily alter subjective experience through their neurochemical effects. Serotonin…”
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The role of the opioid system in alcohol dependence by Nutt, David J

“…The role of the brain opioid system in alcohol dependence has been the subject of much research for over 25 years. This review explores the evidence: firstly…”
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Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse by Korpi, Esa R, den Hollander, Bjørnar, Farooq, Usman, Vashchinkina, Elena, Rajkumar, Ramamoorthy, Nutt, David J, Hyytiä, Petri, Dawe, Gavin S

“…Adaptation of the nervous system to different chemical and physiologic conditions is important for the homeostasis of brain processes and for learning and…”
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The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers by Roseman, Leor, Leech, Robert, Feilding, Amanda, Nutt, David J, Carhart-Harris, Robin L

“…Perturbing a system and observing the consequences is a classic scientific strategy for understanding a phenomenon. Psychedelic drugs perturb consciousness in…”
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Effects of DMT on mental health outcomes in healthy volunteers by Timmermann, Christopher, Zeifman, Richard J., Erritzoe, David, Nutt, David J., Carhart-Harris, Robin L.

“…Psilocybin, a serotonergic psychedelic, is being increasingly researched in clinical studies for the treatment of psychiatric disorders. The relatively lengthy…”
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Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: A revision of the 2005 guidelines from the British Association for Psychopharmacology by Baldwin, David S, Anderson, Ian M, Nutt, David J, Allgulander, Christer, Bandelow, Borwin, den Boer, Johan A, Christmas, David M, Davies, Simon, Fineberg, Naomi, Lidbetter, Nicky, Malizia, Andrea, McCrone, Paul, Nabarro, Daniel, O’Neill, Catherine, Scott, Jan, van der Wee, Nic, Wittchen, Hans-Ulrich

“…This revision of the 2005 British Association for Psychopharmacology guidelines for the evidence-based pharmacological treatment of anxiety disorders provides…”
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Evidence-based guidelines for the pharmacological management of attention deficit hyperactivity disorder: Update on recommendations from the British Association for Psychopharmacology by Bolea-Alamañac, Blanca, Nutt, David J, Adamou, Marios, Asherson, Phillip, Bazire, Stephen, Coghill, David, Heal, David, Müller, Ulrich, Nash, John, Santosh, Paramala, Sayal, Kapil, Sonuga-Barke, Edmund, Young, Susan J

“…Attention deficit hyperactivity disorder (ADHD) is a common condition with a high societal burden. The present guidelines summarise current literature,…”
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