Search Results - "Nutile, Teresa"
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Genetics of PlGF plasma levels highlights a role of its receptors and supports the link between angiogenesis and immunity
Published in Scientific reports (19-08-2021)“…Placental growth factor (PlGF) is a member of the vascular endothelial growth factor family and is involved in bone marrow-derived cell activation, endothelial…”
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2
Age- and sex-related variations in platelet count in Italy: a proposal of reference ranges based on 40987 subjects' data
Published in PloS one (31-01-2013)“…Although several studies demonstrated that platelet count is higher in women, decreases with age, and is influenced by genetic background, most clinical…”
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3
Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels
Published in Nature communications (12-10-2018)“…Elevated serum urate levels can cause gout, an excruciating disease with suboptimal treatment. Previous GWAS identified common variants with modest effects on…”
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4
Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies
Published in PLoS genetics (24-02-2016)“…Vascular endothelial growth factor (VEGF) is an angiogenic and neurotrophic factor, secreted by endothelial cells, known to impact various physiological and…”
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5
Body mass index is directly associated with biomarkers of angiogenesis and inflammation in children and adolescents
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-03-2012)“…Abstract Objectives Childhood obesity is associated with an increased risk of atherosclerosis, which can be mediated by an increase in angiogenesis and…”
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6
Genetics of VEGF serum variation in human isolated populations of cilento: importance of VEGF polymorphisms
Published in PloS one (09-02-2011)“…Vascular Endothelial Growth Factor (VEGF) is the main player in angiogenesis. Because of its crucial role in this process, the study of the genetic factors…”
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7
Whole Exome Sequencing Study of Parkinson Disease and Related Endophenotypes in the Italian Population
Published in Frontiers in neurology (10-01-2020)“…Parkinson Disease (PD) is a complex neurodegenerative disorder characterized by large genetic heterogeneity and missing heritability. Since the genetic…”
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8
Genetic variants modulating CRIPTO serum levels identified by genome-wide association study in Cilento isolates
Published in PLoS genetics (01-01-2015)“…Cripto, the founding member of the EGF-CFC genes, plays an essential role in embryo development and is involved in cancer progression. Cripto is a GPI-anchored…”
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9
Heritability and demographic analyses in the large isolated population of Val Borbera suggest advantages in mapping complex traits genes
Published in PloS one (22-10-2009)“…Isolated populations are a useful resource for mapping complex traits due to shared stable environment, reduced genetic complexity and extended Linkage…”
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10
Genetic and environmental factors influencing the Placental Growth Factor (PGF) variation in two populations
Published in PloS one (20-08-2012)“…Placental Growth Factor (PGF) is a key molecule in angiogenesis. Several studies have revealed an important role of PGF primarily in pathological conditions…”
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11
Identification and Replication of a Novel Obesity Locus on Chromosome 1q24 in Isolated Populations of Cilento
Published in Diabetes (New York, N.Y.) (01-03-2008)“…Identification and Replication of a Novel Obesity Locus on Chromosome 1q24 in Isolated Populations of Cilento Marina Ciullo 1 , Teresa Nutile 1 , Cyril…”
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12
Variation of hemoglobin levels in normal Italian populations from genetic isolates
Published in Haematologica (Roma) (01-09-2008)“…1 DIBIT-San Raffaele Scientific Institute 2 Vita-Salute San Raffaele University, Milan 3 Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" CNR…”
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13
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Published in Nature genetics (01-10-2018)“…High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood…”
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14
Genetic insights into biological mechanisms governing human ovarian ageing
Published in Nature (London) (19-08-2021)“…Reproductive longevity is essential for fertility and influences healthy ageing in women 1 , 2 , but insights into its underlying biological mechanisms and…”
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15
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
Published in Nature genetics (01-06-2017)“…John Perry, Ken Ong and colleagues analyze genotype data on ∼370,000 women and identify 389 independent signals that associate with age at menarche,…”
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16
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
Published in Nature genetics (01-03-2017)“…Mark Caulfield, Paul Elliott and colleagues use data from the UK Biobank to perform genome-wide association analysis for blood pressure traits. They identify…”
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17
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria
Published in Nature communications (11-09-2019)“…Increased levels of the urinary albumin-to-creatinine ratio (UACR) are associated with higher risk of kidney disease progression and cardiovascular events, but…”
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Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
Published in Nature genetics (01-11-2015)“…John Perry and colleagues report the results of a large genome-wide association study meta-analysis to identify variants influencing age at natural menopause…”
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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Published in Nature genetics (01-11-2015)“…John Chambers, Jaspal Kooner, Pim van der Harst, Shyong Tai, Paul Elliott, Jiang He, Norihiro Kato and colleagues performed a genome-wide association study of…”
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20
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
Published in Nature genetics (01-12-2016)“…Melinda Mills, Nicola Barban, Harold Snieder, Marcel den Hoed and colleagues perform a meta-analysis of data from over 300,000 individuals for age at first…”
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