Search Results - "Nussler, Andreas K"

Crucial Role of Vitamin D in the Musculoskeletal System by Wintermeyer, Elke, Ihle, Christoph, Ehnert, Sabrina, Stöckle, Ulrich, Ochs, Gunnar, de Zwart, Peter, Flesch, Ingo, Bahrs, Christian, Nussler, Andreas K

“…Vitamin D is well known to exert multiple functions in bone biology, autoimmune diseases, cell growth, inflammation or neuromuscular and other immune…”
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Extremely low frequency pulsed electromagnetic fields cause antioxidative defense mechanisms in human osteoblasts via induction of •O2− and H2O2 by Ehnert, Sabrina, Fentz, Anne-Kristin, Schreiner, Anna, Birk, Johannes, Wilbrand, Benjamin, Ziegler, Patrick, Reumann, Marie K., Wang, Hongbo, Falldorf, Karsten, Nussler, Andreas K.

“…Recently, we identified a specific extremely low-frequency pulsed electromagnetic field (ELF-PEMF) that supports human osteoblast (hOBs) function in an…”
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Febrile-Range Hyperthermia Can Prevent Toxic Effects of Neutrophil Extracellular Traps on Mesenchymal Stem Cells by Linnemann, Caren, Nussler, Andreas K, Histing, Tina, Ehnert, Sabrina

“…Fracture healing is characterized by an inflammatory phase directly after fracture which has a strong impact on the healing outcome. Neutrophils are strong…”
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Cigarette Smoke Induces the Risk of Metabolic Bone Diseases: Transforming Growth Factor Beta Signaling Impairment via Dysfunctional Primary Cilia Affects Migration, Proliferation, and Differentiation of Human Mesenchymal Stem Cells by Aspera-Werz, Romina H, Chen, Tao, Ehnert, Sabrina, Zhu, Sheng, Fröhlich, Theresa, Nussler, Andreas K

“…It is well established that smoking has detrimental effects on bone integrity and is a preventable risk factor for metabolic bone disorders. Following…”
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5-azacytidine improves the osteogenic differentiation potential of aged human adipose-derived mesenchymal stem cells by DNA demethylation by Yan, Xueying, Ehnert, Sabrina, Culmes, Mihaela, Bachmann, Anastasia, Seeliger, Claudine, Schyschka, Lilianna, Wang, Zhiyong, Rahmanian-Schwarz, Afshin, Stöckle, Ulrich, De Sousa, Paul A, Pelisek, Jaroslav, Nussler, Andreas K

“…The therapeutic value of adipose-derived mesenchymal stem cells (Ad-MSCs) for bone regeneration is critically discussed. A possible reason for reduced…”
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NET Formation Was Reduced via Exposure to Extremely Low-Frequency Pulsed Electromagnetic Fields by Linnemann, Caren, Sahin, Filiz, Chen, Yangmengfan, Falldorf, Karsten, Ronniger, Michael, Histing, Tina, Nussler, Andreas K, Ehnert, Sabrina

“…Fracture-healing is a highly complex and timely orchestrated process. Non-healing fractures are still a major clinical problem and treatment remains difficult…”
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Hepatic Osteodystrophy-Molecular Mechanisms Proposed to Favor Its Development by Ehnert, Sabrina, Aspera-Werz, Romina H, Ruoß, Marc, Dooley, Steven, Hengstler, Jan G, Nadalin, Silvio, Relja, Borna, Badke, Andreas, Nussler, Andreas K

“…Almost all patients with chronic liver diseases (CLD) show altered bone metabolism. Depending on the etiology, this manifests in a severe osteoporosis in up to…”
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From the Clinical Problem to the Basic Research-Co-Culture Models of Osteoblasts and Osteoclasts by Zhu, Sheng, Ehnert, Sabrina, Rouß, Marc, Häussling, Victor, Aspera-Werz, Romina H, Chen, Tao, Nussler, Andreas K

“…Bone tissue undergoes constant remodeling and healing when fracture happens, in order to ensure its structural integrity. In order to better understand open…”
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Altered Secretome of Diabetic Monocytes Could Negatively Influence Fracture Healing—An In Vitro Study by Linnemann, Caren, Savini, Lorena, Rollmann, Mika F., Histing, Tina, Nussler, Andreas K., Ehnert, Sabrina

“…Diabetes mellitus is a main risk factor for delayed fracture healing and fracture non-unions. Successful fracture healing requires stimuli from different…”
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Diclofenac, a NSAID, delays fracture healing in aged mice by Menger, Maximilian M., Stief, Maximilian, Scheuer, Claudia, Rollmann, Mika F., Herath, Steven C., Braun, Benedikt J., Ehnert, Sabrina, Nussler, Andreas K., Menger, Michael D., Laschke, Matthias W., Histing, Tina

“…Nonsteroidal anti-inflammatory drugs (NSAIDs), such as diclofenac, belong to the most prescribed analgesic medication after traumatic injuries. However, there…”
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Bisphosphonates Reduce Smoking-Induced Osteoporotic-Like Alterations by Regulating RANKL/OPG in an Osteoblast and Osteoclast Co-Culture Model by Zhu, Sheng, Häussling, Victor, Aspera-Werz, Romina H, Chen, Tao, Braun, Bianca, Weng, Weidong, Histing, Tina, Nussler, Andreas K

“…Co-culture models have become mandatory for obtaining better insights into bone homeostasis, which relies on the balance between osteoblasts and osteoclasts…”
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Primary Human Chondrocytes Affected by Cigarette Smoke-Therapeutic Challenges by Chen, Tao, Ehnert, Sabrina, Tendulkar, Gauri, Zhu, Sheng, Arnscheidt, Christian, Aspera-Werz, Romina H, Nussler, Andreas K

“…Although several researchers have attested deleterious effects of smoking to the musculoskeletal system, the association between smoking and the onset of…”
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Curcumin prevents chronic alcohol-induced liver disease involving decreasing ROS generation and enhancing antioxidative capacity by Rong, Shuang, Zhao, Yanting, Bao, Wei, Xiao, Xiao, Wang, Di, Nussler, Andreas K., Yan, Hong, Yao, Pin, Liu, Liegang

“…Our previous study found that curcumin, a major active component of turmeric, could ameliorate ethanol-induced hepatocytes oxidative stress in vitro. The…”
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Co-Culture with Human Osteoblasts and Exposure to Extremely Low Frequency Pulsed Electromagnetic Fields Improve Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells by Ehnert, Sabrina, van Griensven, Martijn, Unger, Marina, Scheffler, Hanna, Falldorf, Karsten, Fentz, Anne-Kristin, Seeliger, Claudine, Schröter, Steffen, Nussler, Andreas K, Balmayor, Elizabeth R

“…Human adipose-derived mesenchymal stem cells (Ad-MSCs) have been proposed as suitable option for cell-based therapies to support bone regeneration. In the bone…”
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Associations of Various Physical Activities with Mortality and Life Expectancy are Mediated by Telomere Length by Zhou, Huan-Huan, Jin, Biyu, Liao, Yuxiao, Hu, Yaling, Li, Pengwan, YangLha, Tesring, Liu, Yiran, Xu, Jingwen, Wang, Biyao, Zhu, Minglin, Xiao, Jie, Liu, Jinping, Nüssler, Andreas K., Liu, Liegang, Hao, Xingjie, Chen, Jiuling, Peng, Zhao, Yang, Wei

“…Physical activity (PA) and telomeres both contribute to healthy aging and longevity. To investigate the optimal dosage of various PA for longevity and the role…”
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Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI by Damm, Georg, Nussler, Andreas K., Zeilinger, Katrin, Liu, Jia L., Burkhardt, Britta, Pfeiffer, Elisa, Kegel, Victoria, Seehofer, Daniel

“…Drug induced liver injury (DILI) is an idiosyncratic adverse drug reaction leading to severe liver damage. Kupffer cells (KC) sense hepatic tissue…”
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Exposure to 16 Hz Pulsed Electromagnetic Fields Protect the Structural Integrity of Primary Cilia and Associated TGF-β Signaling in Osteoprogenitor Cells Harmed by Cigarette Smoke by Chen, Yangmengfan, Aspera-Werz, Romina H, Menger, Maximilian M, Falldorf, Karsten, Ronniger, Michael, Stacke, Christina, Histing, Tina, Nussler, Andreas K, Ehnert, Sabrina

“…Cigarette smoking (CS) is one of the main factors related to avoidable diseases and death across the world. Cigarette smoke consists of numerous toxic…”
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Donor Site Location Is Critical for Proliferation, Stem Cell Capacity, and Osteogenic Differentiation of Adipose Mesenchymal Stem/Stromal Cells: Implications for Bone Tissue Engineering by Reumann, Marie K, Linnemann, Caren, Aspera-Werz, Romina H, Arnold, Sigrid, Held, Manuel, Seeliger, Claudine, Nussler, Andreas K, Ehnert, Sabrina

“…Human adipose mesenchymal stem/stromal cells (Ad-MSCs) have been proposed as a suitable option for bone tissue engineering. However, donor age, weight, and…”
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A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation by Weng, Weidong, Zanetti, Filippo, Bovard, David, Braun, Bianca, Ehnert, Sabrina, Uynuk-Ool, Tatiana, Histing, Tina, Hoeng, Julia, Nussler, Andreas K., Aspera-Werz, Romina H.

“…The extracellular matrix regulates cell survival, proliferation, and differentiation. In vitro two-dimensional cell experiments are typically performed on a…”
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TGF-β1 as possible link between loss of bone mineral density and chronic inflammation by Ehnert, Sabrina, Baur, Johannes, Schmitt, Andreas, Neumaier, Markus, Lucke, Martin, Dooley, Steven, Vester, Helen, Wildemann, Britt, Stöckle, Ulrich, Nussler, Andreas K

“…The TGF family plays a key role in bone homeostasis. Systemic or topic application of proteins of this family apparently positively affects bone healing in…”
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