Search Results - "Nussberger, Jürg"

Plasma Aldosterone Is Independently Associated With the Metabolic Syndrome by Bochud, Murielle, Nussberger, Jürg, Bovet, Pascal, Maillard, Marc R, Elston, Robert C, Paccaud, Fred, Shamlaye, Conrad, Burnier, Michel

“…The aim of this study was to analyze the associations of plasma aldosterone and plasma renin activity with the metabolic syndrome and each of its components…”
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Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity by Schäfer, Nicola, Lohmann, Christine, Winnik, Stephan, van Tits, Lambertus J, Miranda, Melroy X, Vergopoulos, Athanasios, Ruschitzka, Frank, Nussberger, Jürg, Berger, Stefan, Lüscher, Thomas F, Verrey, François, Matter, Christian M

“…Aldosterone plays a crucial role in cardiovascular disease. 'Systemic' inhibition of its mineralocorticoid receptor (MR) decreases atherosclerosis by reducing…”
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Optimal blockade of the renin–angiotensin–aldosterone system by Nussberger, Jürg, Bohlender, Jürgen

“…Inhibition of the renin–angiotensin–aldosterone system (RAAS) is a successful therapy for hypertension, heart failure, and renal insufficiency. Overdosing of…”
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Effects of the Peroxisomal Proliferator-Activated Receptor-γ Agonist Pioglitazone on Renal and Hormonal Responses to Salt in Healthy Men by Zanchi, Anne, Chiolero, Arnaud, Maillard, Marc, Nussberger, Jürg, Brunner, Hans-Rudolf, Burnier, Michel

“…Glitazones are used in the treatment of type 2 diabetes as efficient insulin sensitizers. They can, however, induce peripheral edema through an unknown…”
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Local bradykinin generation in hereditary angioedema by Nussberger, Jürg, Cugno, Massimo, Cicardi, Marco, Agostoni, Angelo

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Dilated cardiomyopathy and impaired cardiac hypertrophic response to angiotensin II in mice lacking FGF-2 by Pellieux, C, Foletti, A, Peduto, G, Aubert, J F, Nussberger, J, Beermann, F, Brunner, H R, Pedrazzini, T

“…FGF-2 has been implicated in the cardiac response to hypertrophic stimuli. Angiotensin II (Ang II) contributes to maintain elevated blood pressure in…”
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Cardiovascular Abnormalities with Normal Blood Pressure in Tissue Kallikrein-Deficient Mice by Meneton, Pierre, Bloch-Faure, May, Hagege, Albert A., Ruetten, Hartmut, Huang, Wei, Bergaya, Sonia, Ceiler, Debbie, Gehring, Doris, Martins, Isabelle, Salmon, Georges, Boulanger, Chantal M., Nussberger, Jürg, Crozatier, Bertrand, Gasc, Jean-Marie, Heudes, Didier, Bruneval, Patrick, Doetschman, Tom, Ménard, Joël, Alhenc-Gelas, François

“…Tissue kallikrein is a serine protease thought to be involved in the generation of bioactive peptide kinins in many organs like the kidneys, colon, salivary…”
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Comparative angiotensin II receptor blockade in healthy volunteers: The importance of dosing by Maillard, Marc P., Würzner, Grégoire, Nussberger, Jürg, Centeno, Catherine, Burnier, Michel, Brunner, Hans R.

“…Objectives We have reported previously that 80 mg valsartan and 50 mg losartan provide less receptor blockade than 150 mg irbesartan in normotensive subjects…”
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Renin Inhibition by Aliskiren Prevents Atherosclerosis Progression: Comparison With Irbesartan, Atenolol, and Amlodipine by Nussberger, Jürg, Aubert, Jean-François, Bouzourene, Karima, Pellegrin, Maxime, Hayoz, Daniel, Mazzolai, Lucia

“…Hypertension is associated with increased risk of cardiovascular diseases. Antihypertensive treatment, particularly blockade of the renin-angiotensin system,…”
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No renal dysfunction or salt and water retention in acute mountain sickness at 4,559 m among young resting males after passive ascent by Biollaz, Jérôme, Buclin, Thierry, Hildebrandt, Wulf, Décosterd, Laurent A, Nussberger, Jürg, Swenson, Erik R, Bärtsch, Peter

“…This study examined the role and function of the kidney at high altitude in relation to fluid balance and the development of acute mountain sickness (AMS),…”
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Angiotensinergic Innervation of the Human Right Atrium: Implications for Cardiac Reflexes by Bohlender, Jürgen M, Nussberger, Jürg, Tevaearai, Hendrik, Imboden, Hans

“…Abstract BACKGROUND The right atrium is densely innervated and provides sensory input to important cardiocirculatory reflexes controlling cardiac output and…”
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Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage by FIEBELER, Anette, NUSSBERGER, Jürg, JENG, Arco Y, WEBB, Randy L, LUFT, Friedrich C, MULLER, Dominik N, SHAGDARSUREN, Erdenechimeg, SONG RONG, HILFENHAUS, Georg, AL-SAADI, Nidal, DECHEND, Ralf, WELLNER, Maren, MEINERS, Silke, MASER-GLUTH, Christiane

“…Aldosterone and angiotensin (Ang) II both may cause organ damage. Circulating aldosterone is produced in the adrenals; however, local cardiac synthesis has…”
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Endogenous Angiotensin II Induces Atherosclerotic Plaque Vulnerability and Elicits a Th1 Response in ApoE−/− Mice by Mazzolai, Lucia, Duchosal, Michel A, Korber, Martine, Bouzourene, Karima, Aubert, Jean François, Hao, Hiroyuki, Vallet, Veronique, Brunner, Hans-R, Nussberger, Jürg, Gabbiani, Giulio, Hayoz, Daniel

“…Rupture of vulnerable plaques is the main cause of acute cardiovascular events. However, mechanisms responsible for transforming a stable into a vulnerable…”
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Plasma kinins increase after angiotensin-converting enzyme inhibition in human subjects by Pellacani, A, Brunner, H R, Nussberger, J

“…1. In patients treated with angiotensin-converting enzyme inhibitors, kinin-related effects have been postulated repeatedly, but information on changes in…”
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Pharmacotherapy: Optimal blockade of the renin-angiotensin-aldosterone system by Nussberger, Jürg, Bohlender, Jürgen

“…Inhibition of the renin–angiotensin–aldosterone system (RAAS) is a successful therapy for hypertension, heart failure, and renal insufficiency. Overdosing of…”
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Optimal renin–angiotensin–aldosterone system blockade—wish fulfilled by Nussberger, Jürg, Bohlender, Jürgen

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Swimming Prevents Vulnerable Atherosclerotic Plaque Development in Hypertensive 2-Kidney, 1-Clip Mice by Modulating Angiotensin II Type 1 Receptor Expression Independently From Hemodynamic Changes by Pellegrin, Maxime, Alonso, Florian, Aubert, Jean-François, Bouzourene, Karima, Braunersreuther, Vincent, Mach, François, Haefliger, Jacques-Antoine, Hayoz, Daniel, Berthelot, Alain, Nussberger, Jürg, Laurant, Pascal, Mazzolai, Lucia

“…Exercise is known to reduce cardiovascular risk. However, its role on atherosclerotic plaque stabilization is unknown. Apolipoprotein E mice with vulnerable…”
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Vasopeptidase inhibition and angio-oedema by Messerli, Franz H, Nussberger, Jürg

“…Since most patients reported in the new-drug application for omapatrilat were exposed to the drug for only a short time, the 0.7% rate of angio-oedema must be…”
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Resetting of renal tissular renin–angiotensin and bradykinin–kallikrein systems after unilateral kidney denervation in rats by Bohlender, Jürgen M., Nussberger, Jürg, Birkhäuser, Frédéric, Grouzmann, Eric, Thalmann, George N., Imboden, Hans

“…The renal tissular renin–angiotensin and bradykinin–kallikrein systems control kidney function together with the renal sympathetic innervation but their…”
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OS 18-02 ANTIHYPERTENSIVE TREATMENT AND RISK OF BRAIN ISCHEMIA DUE TO CAROTID STENOSIS IN A SURVEY OF HOSPITALISED PATIENTS AGED 90 YEARS AND OLDER by Bohlender, Jürgen, Nussberger, Jürg, Bohlender, Beate

“…OBJECTIVE:In elderly hypertensive patients, systolic blood pressure (sBP) goals recommended by US and European guidelines (ESH) for the initiation of treatment…”
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