Search Results - "Nusrat, Nada"
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Abemaciclib for malignant pleural mesothelioma – Authors' reply
Published in The lancet oncology (01-06-2022)“…Addition mechanisms of tumour–suppression might involve the PRMT5–MDM4–p53 axis or enhanced tumour immunity.3 To clarify for readers, the original link between…”
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Abemaciclib in patients with p16ink4A-deficient mesothelioma (MiST2): a single-arm, open-label, phase 2 trial
Published in The lancet oncology (01-03-2022)“…Genetically stratified therapy for malignant mesothelioma is unavailable. Mesotheliomas frequently harbour loss of the chromosome 9p21.3 locus (CDKN2A–MTAP),…”
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A gut microbiota rheostat forecasts responsiveness to PD-L1 and VEGF blockade in mesothelioma
Published in Nature communications (21-08-2024)“…Malignant mesothelioma is a rare tumour caused by asbestos exposure that originates mainly from the pleural lining or the peritoneum. Treatment options are…”
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A gut microbiota rheostat to forecast response to PDL1-VEGF blockade in mesothelioma
Published in Journal of clinical oncology (01-06-2023)“…e20534 Background: Targeting of the immune inhibitory PD1-PDL1 axis has proven clinically effective in mesothelioma, despite a low somatic mutation burden, and…”
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Abstract 666: ASTX295 engages p53-mediated apoptosis and an inflammatory response in patient derived mesothelioma explants
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Mesothelioma is a universally lethal, rare cancer caused by asbestos that is lacking effective targeted treatments, particularly in the relapsed…”
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Abstract 1613: Systematic screening for genomic vulnerabilities as drug targets for mesothelioma
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Mesothelioma is a rare, lethal cancer caused by asbestos. Despite recent advances molecularly stratified therapy is lacking, in part due to the…”
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