Search Results - "Nusgens, B."

Hyaluronic acid and extracellular matrix: a primitive molecule? by Nusgens, B-V

“…Hyaluronic acid, or hyaluronan, is a polymer made of the repetition of a unique disaccharidic unit, D-glucuronic acid and D-N-acetylglucosamine, that can reach…”
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ADAMTS-2 functions as anti-angiogenic and anti-tumoral molecule independently of its catalytic activity by Dubail, J, Kesteloot, F, Deroanne, C, Motte, P, Lambert, V, Rakic, J.-M, Lapière, C, Nusgens, B, Colige, A

“…ADAMTS-2 is a metalloproteinase that plays a key role in the processing of fibrillar procollagen precursors into mature collagen molecules by excising the…”
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Vascular Endothelial Growth Factor-111 (VEGF-111) and tendon healing: preliminary results in a rat model of tendon injury by Kaux, J.-F., Janssen, L., Drion, P., Nusgens, B., Libertiaux, V., Pascon, F., Heyeres, A., Hoffmann, A., Lambert, C., Le Goff, C., Denoël, V., Defraigne, J.-O., Rickert, M., Crielaard, J.-M., Colige, A.

“…Tendon lesions are among the most frequent musculoskeletal pathologies. Vascular endothelial growth factor (VEGF) is known to regulate angiogenesis. VEGF-111,…”
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Spontaneous atopic dermatitis due to immune dysregulation in mice lacking Adamts2 and 14 by Dupont, L., Ehx, G., Chantry, M., Monseur, C., Leduc, C., Janssen, L., Cataldo, D., Thiry, M., Jerome, C., Thomassin, J.-M., Nusgens, B., Dubail, J., Baron, F., Colige, A.

“…Since its first description, ADAMTS14 has been considered as an aminoprocollagen peptidase based on its high similarity with ADAMTS3 and ADAMTS2. As its…”
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Domains and Maturation Processes That Regulate the Activity of ADAMTS-2, a Metalloproteinase Cleaving the Aminopropeptide of Fibrillar Procollagens Types I–III and V by Colige, Alain, Ruggiero, Florence, Vandenberghe, Isabel, Dubail, Johanne, Kesteloot, Frederic, Van Beeumen, Jozef, Beschin, Alain, Brys, Lea, Lapière, Charles M, Nusgens, Betty

“…Processing of fibrillar collagens is required to generate collagen monomers able to self-assemble into elongated and cylindrical collagen fibrils. ADAMTS-2…”
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Altered expression of angiogenesis and lymphangiogenesis markers in the uninvolved skin of plaque-type psoriasis by Henno, A., Blacher, S., Lambert, C., Colige, A., Seidel, L., Noël, A., Lapière, C., De La Brassinne, M., Nusgens, B.V.

“…Summary Background  Vascular alterations are significant events in the pathomechanism of psoriasis. A disorder in the mechanisms regulating skin angiogenesis…”
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Positron Emission Tomography (PET) Evaluation of Abdominal Aortic Aneurysm (AAA) by Sakalihasan, N., Van Damme, H., Gomez, P., Rigo, P., Lapiere, C.M., Nusgens, B., Limet, R.

“…Background: aneurysmal disease is associated with an inflammatory cell infiltrate and enzymatic degradation of the vessel wall. Aim of the study: to detect…”
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Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms by SAKALIHASAN, N, DELVENNE, P, NUSGENS, B. V, LIMET, R, LAPIERE, C. M

“…This consistent observation of a reduction of the elastin concentration in abdominal aortic aneurysms (AAAs) has led us to investigate in AAA specimens two…”
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Effects of constitutively active GTPases on fibroblast behavior by Zhang, Z-G, Lambert, C A, Servotte, S, Chometon, G, Eckes, B, Krieg, T, Lapière, C M, Nusgens, B V, Aumailley, M

“…The GTP-binding proteins RhoA, Cdc42 and Rac1 regulate the organization and turnover of the cytoskeleton and cell-matrix adhesions, structures bridging cells…”
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Proanthocyanidins, from Ribes nigrum leaves, reduce endothelial adhesion molecules ICAM-1 and VCAM-1 by Garbacki, N, Kinet, M, Nusgens, B, Desmecht, D, Damas, J

“…The effects of proanthocyanidins (PACs), isolated from blackcurrant (Ribes nigrum L.) leaves, on neutrophil accumulation during inflammatory processes were…”
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In vitro tubulogenesis of endothelial cells by relaxation of the coupling extracellular matrix-cytoskeleton by DEROANNE, Christophe F, LAPIERE, Charles M, NUSGENS, Betty V

“…This investigation aimed at determining the importance of the rigidity of the adhesive support and the participation of the cytoskeleton in tubulogenesis of…”
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The in vitro influences of neurotensin on the motility characteristics of human U373 glioblastoma cells by Servotte, S., Camby, I., Debeir, O., Deroanne, C., Lambert, C. A., Lapière, C. M., Kiss, R., Nusgens, B., Decaestecker, C.

“…Astrocytic tumours are associated with dismal prognoses due to their pronounced ability to diffusely invade the brain parenchyma. Various neuropeptides,…”
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The natural history, including orofacial features of three patients with Ehlers-Danlos syndrome, dermatosparaxis type (EDS type VIIC) by Malfait, Fransiska, De Coster, Peter, Hausser, Ingrid, van Essen, Anthonie J., Franck, Peter, Colige, Alain, Nusgens, Betty, Martens, Luc, De Paepe, Anne

“…Ehlers–Danlos syndrome (EDS) dermatosparaxis type (type VIIC) and the related disease of cattle dermatosparaxis, are recessively inherited connective tissue…”
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Topically Applied Vitamin C Enhances the mRNA Level of Collagens I and III, Their Processing Enzymes and Tissue Inhibitor of Matrix Metalloproteinase 1 in the Human Dermis by NUSGENS, Betty V, HUMBERT, Philippe, ROUGIER, André, COLIGE, Alain C, HAFTEK, Marek, LAMBERT, Charles A, RICHARD, Alain, CREIDI, Pierre, LAPIERE, Charles M

“…Ascorbic acid (vitamin C) is a cofactor required for the function of several hydroxylases and monooxygenases. It is not synthesized in humans and some other…”
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Angiogenesis by fibroblast growth factor 4 is mediated through an autocrine up-regulation of vascular endothelial growth factor expression by DEROANNE, C. F, HAJITOU, A, CALBERG-BACQ, C.-M, NUSGENS, B. V, LAPIERE, C. M

“…The infection of normal mouse mammary EF43 cells by a retroviral vector carrying either Fgf-3 (EF43.Fgf-3) or Fgf-4 (EF43.Fgf-4) cDNA resulted in the…”
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Human Ehlers-Danlos Syndrome Type VII C and Bovine Dermatosparaxis Are Caused by Mutations in the Procollagen I N-Proteinase Gene by Colige, Alain, Sieron, Aleksander L., Li, Shi-Wu, Schwarze, Ulrike, Petty, Elizabeth, Wertelecki, Wladimir, Wilcox, William, Krakow, Deborah, Cohn, Daniel H., Reardon, W., Byers, Peter H., Lapière, Charles M., Prockop, Darwin J., Nusgens, Betty V.

“…Ehlers-Danlos syndrome (EDS) type VIIC is a recessively inherited connective-tissue disorder, characterized by extreme skin fragility, characteristic facies,…”
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A full-UV spectrum absorbing daily use cream protects human skin against biological changes occurring in photoaging by Seité, S., Colige, A., Piquemal-Vivenot, P., Montastier, C., Fourtanier, A., Lapière, C., Nusgens, B.

“…Background: There is overwhelming evidence that exposure of human skin to ultraviolet radiations (UVR) leads to the development of cutaneous photoaging and…”
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Invasion and MMP expression profile in desmoid tumours by DENYS, H, DE WEVER, O, ALMAN, B, CASSIMAN, J-J, NUSGENS, B, KONG, Y, SCIOT, R, LE, A-T, VAN DAM, K, JADIDIZADEH, A, TEJPAR, S, MAREEL, M

“…Desmoid tumours are locally invasive soft tissue tumours in which beta-catenin mediated TCF-dependent transcription is activated. The role of soluble factors…”
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031 VEGF 111 AS A NEW THERAPEUTIC TOOL FOR TENDON LESION by Kaux, J.-F, Drion, P, Libertiaux, V, Pascon, F, Colige, A, Le Goff, C, Lambert, C, Nusgens, B, Gothot, A, Cescotto, S, Defraigne, J.-O, Rickert, M, Crielaard, J.-M

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Cloning and Characterization of ADAMTS-14, a Novel ADAMTS Displaying High Homology with ADAMTS-2 and ADAMTS-3 by Colige, Alain, Vandenberghe, Isabel, Thiry, Marc, Lambert, Charles A., Van Beeumen, Jozef, Li, Shi-Wu, Prockop, Darwin J., Lapière, Charles M., Nusgens, Betty V.

“…The processing of amino- and carboxyl-propeptides of fibrillar collagens is required to generate collagen monomers that correctly assemble into fibrils…”
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