Search Results - "Nusblat, D."

Sporothrix Brasiliensis : A Review of an Emerging South American Fungal Pathogen, Its Related Disease, Presentation and Spread in Argentina by Etchecopaz, Alejandro, Toscanini, María A, Gisbert, Amelia, Mas, Javier, Scarpa, Miguel, Iovannitti, Cristina A, Bendezú, Karla, Nusblat, Alejandro D, Iachini, Ricardo, Cuestas, María L

“…Sporotrichosis, caused by and related species, is the most frequent implantation mycosis in Latin America. In Argentina, over the last 8 years, there have been…”
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The Sterol-C7 desaturase from the ciliate Tetrahymena thermophila is a Rieske Oxygenase, which is highly conserved in animals by Najle, Sebastián R, Nusblat, Alejandro D, Nudel, Clara B, Uttaro, Antonio D

“…The ciliate Tetrahymena thermophila incorporates sterols from its environment that desaturates at positions C5(6), C7(8), and C22(23). Phytosterols are…”
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A Novel Sterol Desaturase-Like Protein Promoting Dealkylation of Phytosterols in Tetrahymena thermophila by Tomazic, Mariela L, Najle, Sebastián R, Nusblat, Alejandro D, Uttaro, Antonio D, Nudel, Clara B

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Genome analysis of sphingolipid metabolism‐related genes in Tetrahymena thermophila and identification of a fatty acid 2‐hydroxylase involved in the sexual stage of conjugation by Cid, Nicolas G., Puca, Gervasio, Nudel, Clara B., Nusblat, Alejandro D.

“…Sphingolipids are bioactive lipids present in all eukaryotes. Tetrahymena thermophila is a ciliate that displays remarkable sphingolipid moieties, that is, the…”
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C-5(6) Sterol Desaturase from Tetrahymena thermophila: Gene Identification and Knockout, Sequence Analysis, and Comparison to Other C-5(6) Sterol Desaturases by Nusblat, Alejandro D, Najle, Sebastián R, Tomazic, Mariela L, Uttaro, Antonio D, Nudel, Clara B

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A novel Tetrahymena thermophila sterol C-22 desaturase belongs to the fatty acid hydroxylase/desaturase superfamily by Sanchez Granel, María L., Siburu, Nicolás G., Fricska, Annamária, Maldonado, Lucas L., Gargiulo, Laura B., Nudel, Clara B., Uttaro, Antonio D., Nusblat, Alejandro D.

“…Sterols in eukaryotic cells play important roles in modulating membrane fluidity and in cell signaling and trafficking. During evolution, a combination of gene…”
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Histoplasma antigens as novel players for the development of new enzyme immunoassays for the serodiagnosis of histoplasmosis: a comparative study of their analytical performance by Laboccetta, Carolina Rodríguez, Fernández, Víctor J Briceño, Garrido, Agustín Videla, Posse, Gladys B, Cuestas, María L, Nusblat, Alejandro D

“…Definitive diagnosis of histoplasmosis relies on culture and/or cytology/histopathology; however, these procedures have limited sensitivity and cultures are…”
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Detection of anti-Histoplasma capsulatum antibodies and seroconversion patterns in critically ill patients with COVID-19: An underdiagnosed fungal entity complicating COVID-19? by Toscanini, María A, Barberis, Fernanda, Benedetti, María F, Garrido, Agustín Videla, Posse, Gladys B, Capece, Paula, Daneri, Gabriela López, Nusblat, Alejandro D, Cuestas, María L

“…Abstract The patients with severe COVID-19 are at increased risk for invasive fungal infections, such as invasive pulmonary aspergillosis and candidiasis,…”
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Development and characterization of an improved formulation of cholesteryl oleate-loaded cationic solid-lipid nanoparticles as an efficient non-viral gene delivery system by Limeres, María J., Suñé-Pou, Marc, Prieto-Sánchez, Silvia, Moreno-Castro, Cristina, Nusblat, Alejandro D., Hernández-Munain, Cristina, Castro, Guillermo R., Suñé, Carlos, Suñé-Negre, Josep M., Cuestas, María L.

“…[Display omitted] •A CO-loaded cSLNs formulation was improved using protamine to enhance performance.•The optimal P:DNA:CO-SLN ratio was 2:1:17 for the highest…”
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Evaluation of the Histoplasma capsulatum 100-kilodalton antigen dot blot for the rapid diagnosis of progressive histoplasmosis in HIV/AIDS patients by Laboccetta, Carolina Rodríguez, Toscanini, María A., Garrido, Agustín Videla, Posse, Gladys B., Capece, Paula, Valdez, Ruth M., Chacón, Yone A., Maglio, Daniel González, Nusblat, Alejandro D., Cuestas, María L.

“…Among people living with HIV (PLHIV), progressive disseminated histoplasmosis (PDH) represents an important cause of mortality. Since antigen detection allows…”
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Evidence of anti-Hcp100 antibodies in COVID-19 critically ill patients with detectable anti-histoplasmin antibodies in a highly endemic area for histoplasmosis by Toscanini, María A, Barberis, Fernanda, Benedetti, Fernanda, Rodríguez Laboccetta, Carolina, Videla Garrido, Agustín, Fernández Briceño, Víctor, Posse, Gladys B, Capece, Paula, Nusblat, Alejandro D, Cuestas, María L

“…Abstract Patients with severe COVID-19 are at increased risk for invasive fungal infections, which are underestimated. Histoplasmosis reactivation in endemic…”
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Histoplasma capsulatum 100-kilodalton antigen: recombinant production, characterization, and evaluation of its possible application in the diagnosis of histoplasmosis by Toscanini, María A., Maglio, Daniel González, Capece, Paula, Posse, Gladys, Iovannitti, Cristina A., Nusblat, Alejandro D., Cuestas, María L.

“…The goal of the present work was to develop a novel reagent with potential for histoplasmosis diagnosis. For this purpose, the genetic sequence of the 100 kDa…”
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The Cryptosporidium parvum gp60 glycoprotein expressed in the ciliate Tetrahymena thermophila is immunoreactive with sera of calves infected with Cryptosporidium oocysts by Elguero, María E., Tomazic, Mariela L., Montes, María G., Florin-Christensen, Mónica, Schnittger, Leonhard, Nusblat, Alejandro D.

“…[Display omitted] •C. parvum gp60 was efficiently expressed in the ciliate T. thermophila.•Gp60 was localized at the ciliate cell surface and oral…”
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Role of recombinant Histoplasma capsulatum 100‐kilodalton antigen in the diagnosis of histoplasmosis among HIV/AIDS patients: Antigenuria and antibodies detection by Toscanini, María A., Laboccetta, Carolina Rodríguez, Videla Garrido, Agustín, Posse, Gladys B., Capece, Paula, Valdez, Ruth M., Chacón, Yone A., González Maglio, Daniel, Nusblat, Alejandro D., Cuestas, María L.

“…Background Diagnosing progressive disseminated histoplasmosis (PDH) is still challenging in many countries where this disease is highly endemic. Definitive…”
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Gene identification and functional characterization of a Δ12 fatty acid desaturase in Tetrahymena thermophila and its influence in homeoviscous adaptation to low temperature by Sanchez Granel, Maria L., Cánepa, Camila, Cid, Nicolas G., Navarro, Juan C., Monroig, Óscar, Verstraeten, Sandra V., Nudel, Clara B., Nusblat, Alejandro D.

“…Homeoviscous adaptation in poikilotherms is based in the regulation of the level of desaturation of fatty acids, variation in phospholipids head groups and…”
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Impact of hepatitis B virus genotype F on in vitro diagnosis: detection efficiency of HBsAg from Amerindian subgenotypes F1b and F4 by Limeres, María J., Gomez, Evangelina R., Noseda, Diego G., Cerrudo, Carolina S., Ghiringhelli, Pablo D., Nusblat, Alejandro D., Cuestas, María L.

“…The influence of the high genetic variability of hepatitis B virus (HBV) on the sensitivity of serological assays has received little attention so far. A major…”
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Incomplete sterols and hopanoids pathways in ciliates: Gene loss and acquisition during evolution as a source of biosynthetic genes by Tomazic, Mariela L., Poklepovich, Tomas J., Nudel, Clara B., Nusblat, Alejandro D.

“…[Display omitted] •Current knowledge in sterol and hopanoid metabolism in ciliates.•Phylogenetic analysis of genesof the pre- and post-squalene pathways,…”
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Genome‐wide Transcriptional Analysis of Tetrahymena thermophila Response to Exogenous Cholesterol by Najle, Sebastián R., Hernández, Josefina, Ocaña‐Pallarès, Eduard, García Siburu, Nicolás, Nusblat, Alejandro D., Nudel, Clara B., Slamovits, Claudio H., Uttaro, Antonio D.

“…The ciliate Tetrahymena thermophila does not require sterols for growth and synthesizes pentacyclic triterpenoid alcohols, mainly tetrahymanol, as sterol…”
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Phylogenomic analysis of integral diiron membrane histidine motif-containing enzymes in ciliates provides insights into their function and evolutionary relationships by Cid, Nicolas G., Sanchez Granel, María L., Montes, María G., Elguero, María E., Nudel, Clara B., Nusblat, Alejandro D.

“…[Display omitted] •High diversity of non-heme IMHME has been identified in seven ciliates genomes.•Gene expansion, reduction and HGT events have modify the…”
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RECURRENCE RISKS FOR PREIMPLANTATION GENETIC TESTING FOR CONGENITAL DISORDER OF GLYCOSYLATION TYPE 1A by Nusblat, D., Cabey, R., Discenza, M., Paulino, N., Sisti, E.

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