Search Results - "Nurse, Colin A."
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Synaptic and paracrine mechanisms at carotid body arterial chemoreceptors
Published in The Journal of physiology (15-08-2014)“…Mammalian carotid bodies are the main peripheral arterial chemoreceptors, strategically located at the bifurcation of the common carotid artery. When…”
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Neurotransmitter and neuromodulatory mechanisms at peripheral arterial chemoreceptors
Published in Experimental physiology (01-06-2010)“…The control of breathing depends critically on sensory inputs to the central pattern generator of the brainstem, arising from peripheral arterial…”
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Single-cell transcriptomic analysis of neuroepithelial cells and other cell types of the gills of zebrafish (Danio rerio) exposed to hypoxia
Published in Scientific reports (16-06-2022)“…The fish gill is a multifunctional organ involved in numerous physiological processes, such as gas exchange and sensing of hypoxia by respiratory…”
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Angiotensin II mobilizes intracellular calcium and activates pannexin‐1 channels in rat carotid body type II cells via AT1 receptors
Published in The Journal of physiology (01-11-2014)“…Key points A locally generating, angiotensin II (ANG II) system is present in the rat carotid body (CB) and up‐regulation of this system occurs in certain…”
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Signal processing at mammalian carotid body chemoreceptors
Published in Seminars in cell & developmental biology (01-01-2013)“…► ATP as an excitatory sensory transmitter in the carotid body. ► Role of ACh, adenosine, 5-HT, GABA, dopamine, ATP, histamine as neuromodulators. ►…”
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Sensory Processing and Integration at the Carotid Body Tripartite Synapse: Neurotransmitter Functions and Effects of Chronic Hypoxia
Published in Frontiers in physiology (16-03-2018)“…Maintenance of homeostasis in the respiratory and cardiovascular systems depends on reflexes that are initiated at specialized peripheral chemoreceptors that…”
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Expanding Role of Dopaminergic Inhibition in Hypercapnic Responses of Cultured Rat Carotid Body Cells: Involvement of Type II Glial Cells
Published in International journal of molecular sciences (30-07-2020)“…Dopamine (DA) is a well-studied neurochemical in the mammalian carotid body (CB), a chemosensory organ involved in O and CO /H homeostasis. DA released from…”
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Hypoxia-regulated catecholamine secretion in chromaffin cells
Published in Cell and tissue research (01-05-2018)“…Adrenal catecholamine (CAT) secretion is a general physiological response of animals to environmental stressors such as hypoxia. This represents an important…”
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P2Y2 receptor activation opens pannexin‐1 channels in rat carotid body type II cells: potential role in amplifying the neurotransmitter ATP
Published in The Journal of physiology (01-09-2012)“…Key points Carotid body (CB) chemoreceptor complexes consist of receptor type I cells, intimately associated with glia‐like type II cells whose function is…”
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10
Role of glial-like type II cells as paracrine modulators of carotid body chemoreception
Published in Physiological genomics (01-04-2018)“…Mammalian carotid bodies (CB) are chemosensory organs that mediate compensatory cardiorespiratory reflexes in response to low blood PO (hypoxemia) and elevated…”
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Expanding role of ATP as a versatile messenger at carotid and aortic body chemoreceptors
Published in The Journal of physiology (01-01-2013)“…In mammals, peripheral arterial chemoreceptors monitor blood chemicals (e.g. O2, CO2, H+, glucose) and maintain homeostasis via initiation of respiratory and…”
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Neurotransmission and neuromodulation in the chemosensory carotid body
Published in Autonomic neuroscience (15-06-2005)“…The mammalian carotid body is a small chemosensory organ that helps maintain the chemical composition of arterial blood via reflex control of ventilation…”
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Ontogeny of O2 and CO2//H+ chemosensitivity in adrenal chromaffin cells: role of innervation
Published in Journal of experimental biology (01-03-2014)“…The adrenal medulla plays a key role in the physiological responses of developing and mature mammals by releasing catecholamines (CAT) during stress. In…”
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Neurotransmitter mechanisms mediating low-glucose signalling in cocultures and fresh tissue slices of rat carotid body
Published in The Journal of physiology (01-02-2007)“…The mammalian carotid body (CB) is a polymodal chemosensor which can detect low blood glucose (hypoglycaemia), leading to increased afferent discharge and…”
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Neuroepithelial oxygen chemoreceptors of the zebrafish gill
Published in The Journal of physiology (01-11-2004)“…In aquatic vertebrates, hypoxia induces physiological changes that arise principally from O 2 chemoreceptors of the gill. Neuroepithelial cells (NECs) of the…”
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Development of oxygen sensing in the gills of zebrafish
Published in Journal of experimental biology (01-04-2005)“…Previous studies have described the morphology, innervation and O(2)-chemoreceptive properties of neuroepithelial cells (NECs) of the zebrafish gill filaments…”
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Confocal immunofluorescence study of rat aortic body chemoreceptors and associated neurons in situ and in vitro
Published in Journal of comparative neurology (1911) (01-04-2011)“…Aortic bodies (ABs) are putative peripheral arterial chemoreceptors, distributed near the aortic arch. Though presumed to be analogous to the well‐studied…”
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Detection of hypoxia-evoked ATP release from chemoreceptor cells of the rat carotid body
Published in Biochemical and biophysical research communications (10-09-2004)“…The carotid body (CB) is a chemosensory organ that detects changes in chemical composition of arterial blood and maintains homeostasis via reflex control of…”
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CO2/pH Chemosensory Signaling in Co-Cultures of Rat Carotid Body Receptors and Petrosal Neurons: Role of ATP and ACh
Published in Journal of neurophysiology (01-12-2004)“…Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada Submitted 13 November 2003; accepted in final form 23 March 2004 The…”
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Co-release of ATP and ACh mediates hypoxic signalling at rat carotid body chemoreceptors
Published in The Journal of physiology (15-05-2000)“…Using functional co-cultures of rat carotid body (CB) O 2 chemoreceptors and âjuxtaposedâ petrosal neurones (JPNs), we tested whether ATP and ACh acted as…”
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