Search Results - "Nurmohamed, Michael"
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Cardiovascular comorbidity in rheumatic diseases
Published in Nature reviews. Rheumatology (01-12-2015)“…Key Points Patients with inflammatory joint diseases (IJDs) have an increased burden of cardiovascular disease compared with the general population…”
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Methotrexate reduces immunogenicity in adalimumab treated rheumatoid arthritis patients in a dose dependent manner
Published in Annals of the rheumatic diseases (01-11-2012)Get more information
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Is atherosclerosis an autoimmune disease?
Published in BMC medicine (18-03-2014)“…Immunologic research into pathogenic mechanisms operating in autoimmune-mediated atherosclerosis initially focused on adaptive immunity. Current interest is…”
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Cardiovascular effects of approved drugs for rheumatoid arthritis
Published in Nature reviews. Rheumatology (01-05-2021)“…The risk of cardiovascular disease is increased in patients with rheumatoid arthritis compared with the general population owing to the influence of…”
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Key findings towards optimising adalimumab treatment: the concentration-effect curve
Published in Annals of the rheumatic diseases (01-03-2015)“…To determine a concentration-effect curve of adalimumab in rheumatoid arthritis (RA) patients taking into account the effect of methotrexate (MTX) on…”
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Cardiovascular Disease Risk in Rheumatoid Arthritis Anno 2022
Published in Journal of clinical medicine (11-05-2022)“…The risk for developing cardiovascular diseases (CVD) in rheumatoid arthritis (RA) patients is 1.5 times higher compared to the general population. This risk…”
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Can personalized use of NSAIDs be a reality in the clinic?
Published in Nature reviews. Rheumatology (01-07-2019)“…The use of NSAIDs in rheumatology could be improved by an appropriate risk scoring system that accounts for adverse events such as bleeding and thrombosis…”
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Cardiovascular risk in rheumatoid arthritis
Published in Autoimmunity reviews (01-07-2009)“…Abstract The increased mortality in rheumatoid arthritis (RA) is mainly due to (atherosclerotic) cardiovascular disease. The cardiovascular morbidity is also…”
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Comment on: Proprotein convertase subtilisin/kexin type 9 in the dyslipidaemia of patients with axial spondyloarthritis is related to disease activity
Published in Rheumatology (01-08-2021)Get full text
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Cardiovascular disease in inflammatory rheumatic diseases
Published in Best practice & research. Clinical rheumatology (01-10-2016)“…Abstract Chronic inflammatory rheumatic diseases (IRD), including rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis, are prevalent…”
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Correspondence on "Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: results from the COVID-19 global rheumatology alliance physician registry"
Published in Annals of the rheumatic diseases (01-08-2023)Get more information
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A neutrophil signature is strongly associated with increased cardiovascular risk in gout
Published in Rheumatology (Oxford, England) (18-06-2021)“…Abstract Objective To investigate the association between neutrophil activation and cardiovascular risk in gout patients. We hypothesize that neutrophil…”
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Confounding by indication probably distorts the relationship between steroid use and cardiovascular disease in rheumatoid arthritis: results from a prospective cohort study
Published in PloS one (30-01-2014)“…To evaluate the risk of cardiovascular disease in patients with rheumatoid arthritis exposed to glucocorticoids. Retrospective analysis of exposure to…”
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Editorial: Treat to Target in Rheumatoid Arthritis: Good for the Joints as Well as the Heart?
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-06-2015)Get full text
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Does Adding Single‐Nucleotide Polymorphisms to Risk Algorithms Improve Cardiovascular Disease Risk Prediction in Rheumatoid Arthritis? An Internal and External Validation of a Clinical Risk Score
Published in Arthritis care & research (2010) (01-10-2024)“…Objective Current risk algorithms do not accurately predict cardiovascular disease (CVD) risk in rheumatoid arthritis (RA). An area of interest is that of…”
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A meta‐analysis of methotrexate polyglutamates in relation to efficacy and toxicity of methotrexate in inflammatory arthritis, colitis and dermatitis
Published in British journal of clinical pharmacology (01-01-2023)“…Aims In immune‐mediated inflammatory diseases (IMIDs), early symptom control is a key therapeutic goal. Methotrexate (MTX) is the first‐line treatment across…”
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Cardiovascular risk in persons at risk of developing rheumatoid arthritis
Published in PloS one (03-08-2020)“…Background Rheumatoid arthritis (RA) is associated with an increased cardiovascular disease (CVD) risk which may start even before diagnosis. To explore this…”
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Changes in Tumor Necrosis Factor Inhibitor Drug Survival in Patients With Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis Over 15 Years
Published in Journal of rheumatology (01-01-2024)“…Objective To study changes in retention of first biologic disease-modifying antirheumatic drug (DMARD) therapy over a period of 15 years in an inception cohort…”
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Development of Antidrug Antibodies Against Adalimumab and Association With Disease Activity and Treatment Failure During Long-term Follow-up
Published in JAMA : the journal of the American Medical Association (13-04-2011)“…CONTEXT Short-term data on the immunogenicity of monoclonal antibodies showed associations between the development of antidrug antibodies and diminished serum…”
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Cardiovascular comorbidities in patients with psoriatic arthritis: a systematic review
Published in Annals of the rheumatic diseases (01-02-2013)“…Data regarding cardiovascular comorbidity and cardiovascular risk factors in patients with psoriatic arthritis (PsA) are limited. To evaluate the…”
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