Search Results - "Nurmi, K."

The biological activity of serum bacterial lipopolysaccharides associates with disease activity and likelihood of achieving remission in patients with rheumatoid arthritis by Parantainen, J, Barreto, G, Koivuniemi, R, Kautiainen, H, Nordström, D, Moilanen, E, Hämäläinen, M, Leirisalo-Repo, M, Nurmi, K, Eklund, K K

“…Dysbiotic intestinal and oral microbiota have been implicated in the pathogenesis of rheumatoid arthritis (RA), but the mechanisms how microbiota could impact…”
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Pathogenic Variant Spectrum in Breast Cancer Risk Genes in Finnish Patients by Nurmi, Anna K, Suvanto, Maija, Dennis, Joe, Aittomäki, Kristiina, Blomqvist, Carl, Nevanlinna, Heli

“…Recurrent pathogenic variants have been detected in several breast and ovarian cancer (BC/OC) risk genes in the Finnish population. We conducted a gene-panel…”
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Presence of gastrointestinal symptoms in IgA nephropathy: a cross-sectional study by Pohjonen, Jussi T, Kaukinen, Katri M, Metso, Martti J, Nurmi, Rakel Kk, Huhtala, Heini Sa, Pörsti, Ilkka H, Mustonen, Jukka T, Mäkelä, Satu M

“…Gastrointestinal (GI) symptoms are common in end-stage kidney disease. Mounting evidence indicates that the intestine plays an important role in the…”
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On‐call stress among Finnish anaesthetists by Lindfors, P. M., Nurmi, K. E., Meretoja, O. A., Luukkonen, R. A., Viljanen, A.‐M., Leino, T. J., Härmä, M I.

“…Summary We investigated on‐call stress and its consequences among anaesthetists. A questionnaire was sent to all working Finnish anaesthetists (n = 550), with…”
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Ethanol induces apoptosis in human mast cells by Nurmi, K., Methuen, T., Mäki, T., Lindstedt, K.A., Kovanen, P.T., Sandler, C., Eklund, K.K.

“…Alcohol abuse is associated with increased frequency of infections attributed to ethanol-induced immune suppression. The precise mechanism of immune…”
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The substitution pattern in cationised and oxidised potato starch granules by Manelius, Robin, Buléon, Alain, Nurmi, Kari, Bertoft, Eric

“…The distribution pattern of substituents within the granules and the components of two cationised and two oxidised potato starches was studied. The level of…”
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High-performance liquid chromatographic separation and identification of phenolic compounds from leaves of Betula pubescens and Betula pendula by Ossipov, V., Nurmi, K., Loponen, J., Haukioja, E., Pihlaja, K.

“…The following major phenolics with non-flavonoid structure were identified from leaves of Betula pubescens (white birch) and Betula pendula (silver birch):…”
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Preparation of starch betainate: a novel cationic starch derivative by Granö, H, Yli-Kauhaluoma, J, Suortti, T, Käki, J, Nurmi, K

“…A novel cationic starch derivative was prepared by esterifying native potato starch with anhydrous betaine. The reaction was performed on native potato starch…”
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Damaging heterozygous mutations in NFKB1 lead to diverse immunologic phenotypes by Kaustio, Meri, MSc, Haapaniemi, Emma, MD, PhD, Göös, Helka, MSc, Hautala, Timo, MD, PhD, Park, Giljun, PhD, Syrjänen, Jaana, MD, PhD, Einarsdottir, Elisabet, PhD, Sahu, Biswajyoti, PhD, Kilpinen, Sanna, MD, PhD, Rounioja, Samuli, MD, PhD, Fogarty, Christopher L., MSc, Glumoff, Virpi, PhD, Kulmala, Petri, MD, PhD, Katayama, Shintaro, PhD, Tamene, Fitsum, MSc, Trotta, Luca, MSc, Morgunova, Ekaterina, PhD, Krjutškov, Kaarel, PhD, Nurmi, Katariina, PhD, Eklund, Kari, MD, PhD, Lagerstedt, Anssi, MD, PhD, Helminen, Merja, MD, PhD, Martelius, Timi, MD, PhD, Mustjoki, Satu, MD, PhD, Taipale, Jussi, PhD, Saarela, Janna, MD, PhD, Kere, Juha, MD, PhD, Varjosalo, Markku, PhD, Seppänen, Mikko, MD, PhD

“…Background The nuclear factor κ light-chain enhancer of activated B cells (NF-κB) signaling pathway is a key regulator of immune responses. Accordingly,…”
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Hydroxychloroquine reduces interleukin-6 levels after myocardial infarction: The randomized, double-blind, placebo-controlled OXI pilot trial by Ulander, Lotta, Tolppanen, Heli, Hartman, Otto, Rissanen, Tuomas T., Paakkanen, Riitta, Kuusisto, Jouni, Anttonen, Olli, Nieminen, Tuomo, Yrjölä, Jaana, Ryysy, Ransu, Drews, Teemu, Utriainen, Seppo, Karjalainen, Pasi, Anttila, Ismo, Nurmi, Katariina, Silventoinen, Kristiina, Koskinen, Miika, Kovanen, Petri T., Lehtonen, Jukka, Eklund, Kari K., Sinisalo, Juha

“…To determine the anti-inflammatory effect and safety of hydroxychloroquine after acute myocardial infarction. In this multicenter, double-blind,…”
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Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy by Göös, Helka, Fogarty, Christopher L., Sahu, Biswajyoti, Plagnol, Vincent, Rajamäki, Kristiina, Nurmi, Katariina, Liu, Xiaonan, Einarsdottir, Elisabet, Jouppila, Annukka, Pettersson, Tom, Vihinen, Helena, Krjutskov, Kaarel, Saavalainen, Päivi, Järvinen, Asko, Muurinen, Mari, Greco, Dario, Scala, Giovanni, Curtis, James, Nordström, Dan, Flaumenhaft, Robert, Vaarala, Outi, Kovanen, Panu E., Keskitalo, Salla, Ranki, Annamari, Kere, Juha, Lehto, Markku, Notarangelo, Luigi D., Nejentsev, Sergey, Eklund, Kari K., Varjosalo, Markku, Taipale, Jussi, Seppänen, Mikko R.J.

“…CCAAT enhancer–binding protein epsilon (C/EBPε) is a transcription factor involved in late myeloid lineage differentiation and cellular function. The only…”
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HPLC isolation and identification of flavonoids from white birch Betula pubescens leaves by Ossipov, V., Nurmi, K., Loponen, J., Prokopiev, N., Haukioja, E., Pihlaja, K.

“…Nine flavonoid glycosides were isolated from birch leaves by preparative HPLC and their structures identified by chromatographic (analytical HPLC), chemical…”
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immunohistochemical characterisation of an SV40-immortalised human corneal epithelial cell line by Huhtala, Anne, Nurmi, Sami K, Tähti, Hanna, Salminen, Lotta, Alajuuma, Päivi, Rantala, Immo, Helin, Heikki, Uusitalo, Hannu

“…Alternatives to the Draize rabbit eye irritation test are currently being investigated. Because of morphological and biochemical differences between the rabbit…”
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Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells by Hetemäki, Iivo, Kaustio, Meri, Kinnunen, Matias, Heikkilä, Nelli, Keskitalo, Salla, Nowlan, Kirsten, Miettinen, Simo, Sarkkinen, Joona, Glumoff, Virpi, Andersson, Noora, Kettunen, Kaisa, Vanhanen, Reetta, Nurmi, Katariina, Eklund, Kari K, Dunkel, Johannes, Mäyränpää, Mikko I, Schlums, Heinrich, Arstila, T Petteri, Kisand, Kai, Bryceson, Yenan T, Peterson, Pärt, Otava, Ulla, Syrjänen, Jaana, Saarela, Janna, Varjosalo, Markku, Kekäläinen, Eliisa

“…The Ikaros family transcription factors regulate lymphocyte development. Loss-of-function variants in cause primary immunodeficiency, but Ikaros family members…”
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Hemin and Cobalt Protoporphyrin Inhibit NLRP3 Inflammasome Activation by Enhancing Autophagy: A Novel Mechanism of Inflammasome Regulation by Nurmi, Katariina, Kareinen, Ilona, Virkanen, Juhani, Rajamäki, Kristiina, Kouri, Vesa-Petteri, Vaali, Kirsi, Levonen, Anna-Liisa, Fyhrquist, Nanna, Matikainen, Sampsa, Kovanen, Petri T., Eklund, Kari K.

“…Inflammasomes are intracellular protein platforms, which, upon activation, produce the highly proinflammatory cytokines interleukin (IL)-1β and IL-18. Heme,…”
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Enhanced activation of the renin-angiotensin-aldosterone system in chronic cigarette smokers: a study of monozygotic twin pairs discordant for smoking by Laustiola, K E, Lassila, R, Nurmi, A K

“…Plasma renin activity (PRA) and aldosterone concentration were measured before and during submaximal exercise in 10 male monozygotic twin pairs who were…”
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Native and oxidised lipoproteins negatively regulate the serum amyloid A‐induced NLRP3 inflammasome activation in human macrophages by Nurmi, Katariina, Niemi, Katri, Kareinen, Ilona, Silventoinen, Kristiina, Lorey, Martina B, Chen, Yan, Kouri, Vesa‐Petteri, Parantainen, Jukka, Juutilainen, Timo, Öörni, Katariina, Kovanen, Petri T, Nordström, Dan, Matikainen, Sampsa, Eklund, Kari K

“…Objectives The NLRP3 inflammasome plays a key role in arterial wall inflammation. In this study, we elucidated the role of serum lipoproteins in the regulation…”
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Pharmacokinetics of clodronate in patients with metastatic breast cancer by Pentikäinen, P J, Elomaa, I, Nurmi, A K, Kärkkäinen, S

“…Pharmacokinetics of clodronate was studied in six breast cancer patients with only bone metastases. 14C-clodronate was administered intravenously (10 muCi/200…”
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Inhibition of angiotensin-converting enzyme with quinapril (CI-906): investigation of antihypertensive mechanisms in spontaneously hypertensive rats by Säynävälammi, P, Pörsti, I, Nurmi, A K, Seppälä, E, Metsä-Ketelä, T, Tuomisto, L, Manninen, V, Vapaatalo, H

“…Treatment for 8 days with a new nonsulfhydryl angiotensin-converting enzyme inhibitor, quinapril (CI-906), produced a marked and progressive reduction in the…”
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Serum Trypsinlike Immunoreactivity Measurement for the Diagnosis of Subclinical Exocrine Pancreatic Insufficiency by Wiberg, Maria E., Nurmi, Anna-Kaisa, Westermarck, Elias

“…Dogs (n = 158) with serum trypsinlike immunoreactivity (TLI) concentrations ≤ 5.0 μg/L were studied. The diagnosis of clinical exocrine pancreatic…”
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