Search Results - "Nurgali, Kulmira"
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The emerging antioxidant paradigm of mesenchymal stem cell therapy
Published in Stem cells translational medicine (01-09-2020)“…Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for the treatment of diverse diseases, with many promising outcomes…”
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Editorial: Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?
Published in Frontiers in pharmacology (22-03-2018)Get full text
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The Role of Tryptophan Metabolites in Neuropsychiatric Disorders
Published in International journal of molecular sciences (01-09-2022)“…In recent decades, neuropsychiatric disorders such as major depressive disorder, schizophrenia, bipolar, etc., have become a global health concern, causing…”
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Eosinophils in Cancer: Favourable or Unfavourable?
Published in Current medicinal chemistry (01-02-2016)“…Eosinophils are granulocytic leukocytes residing in blood and tissues in the lung, breast, gastrointestinal and reproductive systems. Eosinophilia is uncommon…”
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Role of the nervous system in cancer metastasis
Published in Journal of experimental & clinical cancer research (15-01-2018)“…Cancer remains as one of the leading cause of death worldwide. The development of cancer involves an intricate process, wherein many identified and…”
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Colorectal Cancer Chemotherapy: The Evolution of Treatment and New Approaches
Published in Current medicinal chemistry (01-01-2017)“…Colorectal cancer (CRC) is one the greatest contributors to cancer related mortality. Although 5 year survival rate for patients at the early stage of CRC…”
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The Complex Interaction between the Tumor Micro-Environment and Immune Checkpoints in Breast Cancer
Published in Cancers (19-08-2019)“…The progression of breast cancer and its association with clinical outcome and treatment remain largely unexplored. Accumulating data has highlighted the…”
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Methamphetamine: Effects on the brain, gut and immune system
Published in Pharmacological research (01-06-2017)“…[Display omitted] Methamphetamine (METH) is a powerful central nervous system stimulant which elevates mood, alertness, energy levels and concentration in the…”
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Translocation and dissemination of commensal bacteria in post-stroke infection
Published in Nature medicine (01-11-2016)“…In humans and rodent models, commensal gut bacteria contribute to post-stroke infection. Experimental stroke in rodents causes gut barrier dysfunction and…”
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Platinum accumulation in the brain and alteration in the central regulation of cardiovascular and respiratory functions in oxaliplatin-treated rats
Published in Pflügers Archiv (01-01-2021)“…Oxaliplatin is a platinum-based alkylating chemotherapeutic agent used for cancer treatment. Neurotoxicity is one of its major adverse effects that often…”
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Neuroinflammation as an etiological trigger for depression comorbid with inflammatory bowel disease
Published in Journal of neuroinflammation (04-01-2022)“…Patients with inflammatory bowel disease (IBD) suffer from depression at higher rates than the general population. An etiological trigger of depressive…”
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Mechanisms of Chemotherapy-Induced Neurotoxicity
Published in Frontiers in pharmacology (28-03-2022)“…Since the first clinical trials conducted after World War II, chemotherapeutic drugs have been extensively used in the clinic as the main cancer treatment…”
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13
Cholinergic signaling influences the expression of immune checkpoint inhibitors, PD-L1 and PD-L2, and tumor hallmarks in human colorectal cancer tissues and cell lines
Published in BMC cancer (12-10-2023)“…Abstract Background Cancer cells express immunosuppressive molecules, such as programmed death ligands (PD-L)1 and PD-L2, enabling evasion from the host’s…”
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Neurotoxicity Associated with Platinum-Based Anti-Cancer Agents: What are the Implications of Copper Transporters?
Published in Current medicinal chemistry (01-01-2017)“…Platinum-based anti-cancer agents, which include cisplatin, carboplatin and oxaliplatin, are an important class of drugs used in clinical setting to treat a…”
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15
Chemotherapy-Induced Constipation and Diarrhea: Pathophysiology, Current and Emerging Treatments
Published in Frontiers in pharmacology (03-11-2016)“…Gastrointestinal (GI) side-effects of chemotherapy are a debilitating and often overlooked clinical hurdle in cancer management. Chemotherapy-induced…”
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Blocking Muscarinic Receptor 3 Attenuates Tumor Growth and Decreases Immunosuppressive and Cholinergic Markers in an Orthotopic Mouse Model of Colorectal Cancer
Published in International journal of molecular sciences (29-12-2022)“…Tumor cells have evolved to express immunosuppressive molecules allowing their evasion from the host's immune system. These molecules include programmed death…”
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Leucocyte-Rich Platelet-Rich Plasma Enhances Fibroblast and Extracellular Matrix Activity: Implications in Wound Healing
Published in International journal of molecular sciences (06-09-2020)“…Platelet-rich plasma (PRP) is an autologous blood product that contains a high concentration of platelets and leucocytes, which are fundamental fibroblast…”
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Impact of chemotherapy on gastrointestinal functions and the enteric nervous system
Published in Maturitas (01-11-2017)“…•Chemotherapy before or after surgery is the main treatment for colorectal cancer.•Gastrointestinal toxicity is a severe side-effect of…”
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Tryptophan and Substance Abuse: Mechanisms and Impact
Published in International journal of molecular sciences (01-02-2023)“…Addiction, the continuous misuse of addictive material, causes long-term dysfunction in the neurological system. It substantially affects the control strength…”
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Anti-Tumor Effects of Vitamin B2, B6 and B9 in Promonocytic Lymphoma Cells
Published in International journal of molecular sciences (01-08-2019)“…Chronic inflammation can lead to tumour initiation and progression. Vitamin B complex has the ability to regulate the immune response and, therefore,…”
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