Search Results - "Nunn, Anthony J"

Development of the Liverpool Adverse Drug Reaction Avoidability Assessment Tool by Bracken, Louise E, Nunn, Anthony J, Kirkham, Jamie J, Peak, Matthew, Arnott, Janine, Smyth, Rosalind L, Pirmohamed, Munir, Turner, Mark A

“…To develop and test a new tool to assess the avoidability of adverse drug reactions that is suitable for use in paediatrics but which is also applicable to a…”
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Potentially harmful excipients in neonatal medicines: a pan-European observational study by Nellis, Georgi, Metsvaht, Tuuli, Varendi, Heili, Toompere, Karolin, Lass, Jana, Mesek, Inge, Nunn, Anthony J, Turner, Mark A, Lutsar, Irja

“…ObjectivesWe aimed to describe administration of eight potentially harmful excipients of interest (EOI)—parabens, polysorbate 80, propylene glycol, benzoates,…”
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Adverse drug reactions causing admission to a paediatric hospital by Gallagher, Ruairi M, Mason, Jennifer R, Bird, Kim A, Kirkham, Jamie J, Peak, Matthew, Williamson, Paula R, Nunn, Anthony J, Turner, Mark A, Pirmohamed, Munir, Smyth, Rosalind L

“…To obtain reliable information about the incidence of adverse drug reactions, and identify potential areas where intervention may reduce the burden of…”
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Development and inter-rater reliability of the Liverpool adverse drug reaction causality assessment tool by Gallagher, Ruairi M, Kirkham, Jamie J, Mason, Jennifer R, Bird, Kim A, Williamson, Paula R, Nunn, Anthony J, Turner, Mark A, Smyth, Rosalind L, Pirmohamed, Munir

“…To develop and test a new adverse drug reaction (ADR) causality assessment tool (CAT). A comparison between seven assessors of a new CAT, formulated by an…”
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Enhancing communication about paediatric medicines: lessons from a qualitative study of parents' experiences of their child's suspected adverse drug reaction by Arnott, Janine, Hesselgreaves, Hannah, Nunn, Anthony J, Peak, Matthew, Pirmohamed, Munir, Smyth, Rosalind L, Turner, Mark A, Young, Bridget

“…There is little research on parents' experiences of suspected adverse drug reactions in their children and hence little evidence to guide clinicians when…”
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Prophylactic ranitidine treatment in critically ill children – a population pharmacokinetic study by Hawwa, Ahmed F., Westwood, Paul M., Collier, Paul S., Millership, Jeffrey S., Yakkundi, Shirish, Thurley, Gillian, Shields, Mike D., Nunn, Anthony J., Halliday, Henry L., McElnay, James C.

“…Aims To characterize the population pharmacokinetics of ranitidine in critically ill children and to determine the influence of various clinical and…”
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Adverse drug reactions and off‐label and unlicensed medicines in children: a prospective cohort study of unplanned admissions to a paediatric hospital by Bellis, Jennifer R., Kirkham, Jamie J., Nunn, Anthony J., Pirmohamed, Munir

“…Aims To examine the impact of off‐label and unlicensed (OLUL) prescribing on adverse drug reactions (ADRs) causing unplanned admissions to a paediatric…”
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A systematic review of the use of dosage form manipulation to obtain required doses to inform use of manipulation in paediatric practice by Richey, Roberta H., Hughes, Clare, Craig, Jean V., Shah, Utpal U., Ford, James L., Barker, Catrin E., Peak, Matthew, Nunn, Anthony J., Turner, Mark A.

“…[Display omitted] This study sought to determine whether there is an evidence base for drug manipulation to obtain the required dose, a common feature of…”
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Development and evaluation of an assessment of the age-appropriateness/inappropriateness of formulations used in children by Duncan, Jennifer C., Bracken, Louise E., Nunn, Anthony J., Peak, Matthew, Turner, Mark A.

“…Background Medicines designed for adults may be inappropriate for use in children in terms of strength, dosage form and/or excipient content. There is…”
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High variability in the dosing of commonly used antibiotics revealed by a Europe-wide point prevalence study: implications for research and dissemination by Metsvaht, Tuuli, Nellis, Georgi, Varendi, Heili, Nunn, Anthony J, Graham, Susan, Rieutord, Andre, Storme, Thomas, McElnay, James, Mulla, Hussain, Turner, Mark A, Lutsar, Irja

“…Antibiotic dosing in neonates varies between countries and centres, suggesting suboptimal exposures for some neonates. We aimed to describe variations and…”
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Adverse drug reactions and off-label and unlicensed medicines in children: a nested case-control study of inpatients in a pediatric hospital by Bellis, Jennifer R, Kirkham, Jamie J, Thiesen, Signe, Conroy, Elizabeth J, Bracken, Louise E, Mannix, Helena L, Bird, Kim A, Duncan, Jennifer C, Peak, Matthew, Turner, Mark A, Smyth, Rosalind L, Nunn, Anthony J, Pirmohamed, Munir

“…Off-label and unlicensed (OLUL) prescribing has been prevalent in pediatric practice. Using data from a prospective cohort study of adverse drug reactions…”
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Manipulation of drugs to achieve the required dose is intrinsic to paediatric practice but is not supported by guidelines or evidence by Richey, Roberta H, Shah, Utpal U, Peak, Matthew, Craig, Jean V, Ford, James L, Barker, Catrin E, Nunn, Anthony J, Turner, Mark A

“…A lack of age-appropriate formulations can make it difficult to administer medicines to children. A manipulation of the dosage form may be required to achieve…”
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Medicines prescription patterns in European neonatal units by Mesek, Inge, Nellis, Georgi, Lass, Jana, Metsvaht, Tuuli, Varendi, Heili, Visk, Helle, Turner, Mark A., Nunn, Anthony J., Duncan, Jennifer, Lutsar, Irja

“…Background Hospitalized neonates receive the highest number of drugs compared to all other age groups, but consumption rates vary between studies depending on…”
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Incidence, characteristics and risk factors of adverse drug reactions in hospitalized children - a prospective observational cohort study of 6,601 admissions by Thiesen, Signe, Conroy, Elizabeth J, Bellis, Jennifer R, Bracken, Louise E, Mannix, Helena L, Bird, Kim A, Duncan, Jennifer C, Cresswell, Lynne, Kirkham, Jamie J, Peak, Matthew, Williamson, Paula R, Nunn, Anthony J, Turner, Mark A, Pirmohamed, Munir, Smyth, Rosalind L

“…Adverse drug reactions (ADRs) are an important cause of harm in children. Current data are incomplete due to methodological differences between studies: only…”
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Product Substitution as a Way Forward in Avoiding Potentially Harmful Excipients in Neonates by Nellis, Georgi, Metsvaht, Tuuli, Varendi, Heili, Lass, Jana, Duncan, Jennifer, Nunn, Anthony J., Turner, Mark A., Lutsar, Irja

“…Objectives Our objectives were to explore the possibility of avoiding neonatal exposure to potentially harmful excipients of interest (EOI)—parabens,…”
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What can we learn from parents about enhancing participation in pharmacovigilance? by Arnott, Janine, Hesselgreaves, Hannah, Nunn, Anthony J., Peak, Matthew, Pirmohamed, Munir, Smyth, Rosalind L., Turner, Mark A., Young, Bridget

“…Aims To investigate parents' views and experiences of direct reporting of a suspected ADR in their child. Methods We audio‐recorded semi‐structured qualitative…”
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MODRIC – Manipulation of drugs in children by Richey, Roberta H., Craig, Jean V., Shah, Utpal U., Nunn, Anthony J., Turner, Mark A., Barker, Catrin E., Ford, James L., Peak, Matthew

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Unlicensed and off label drug use in paediatric wards: prospective study by Turner, Sean, Longworth, Alexandra, Nunn, Anthony J, Choonara, Imti

“…Abstract Objective: To determine the extent of use in children in hospital of drugs that are not specifically licensed for use in children (unlicensed) and of…”
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Clinical coding of prospectively identified paediatric adverse drug reactions--a retrospective review of patient records by Bellis, Jennifer R, Kirkham, Jamie J, Nunn, Anthony J, Pirmohamed, Munir

“…National Health Service (NHS) hospitals in the UK use a system of coding for patient episodes. The coding system used is the International Classification of…”
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A Comprehensive List of Items to be Included on a Pediatric Drug Monograph by Kelly, Lauren E, Ito, Shinya, Woods, David, Nunn, Anthony J, Taketomo, Carol, de Hoog, Matthijs, Offringa, Martin

“…Children require special considerations for drug prescribing. Drug information summarized in a formulary containing drug monographs is essential for safe and…”
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