Search Results - "Nunez, Shakayla"
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P311, a novel intrinsically disordered protein, regulates adipocyte development
Published in Biochemical and biophysical research communications (12-07-2019)“…Adipocyte development and adipose tissue expansion have many implications for human diseases, including obesity. Obesity is a debilitating disorder and a risk…”
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2
Multivariate transcriptome analysis identifies networks and key drivers of chronic lymphocytic leukemia relapse risk and patient survival
Published in BMC medical genomics (29-06-2021)“…Chronic lymphocytic leukemia (CLL) is an indolent heme malignancy characterized by the accumulation of CD5 CD19 B cells and episodes of relapse. The biological…”
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3
Identification of Gene Co-Expression Networks Associated with Consensus Molecular Subtype-1 of Colorectal Cancer
Published in Cancers (20-11-2021)“…Colorectal cancer (CRC) is driven in part by dysregulated Wnt, Ras-Raf-MAPK, TGF-β, and PI3K-Akt signaling. The progression of CRC is also promoted by…”
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4
Resistance Mechanisms to Anti-Epidermal Growth Factor Receptor Therapy in RAS/RAF Wild-Type Colorectal Cancer Vary by Regimen and Line of Therapy
Published in Journal of clinical oncology (20-01-2023)“…Acquired resistance to anti-epidermal growth factor receptor (EGFR) inhibitor (EGFRi) therapy in colorectal cancer (CRC) has previously been explained by the…”
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5
Resistance mechanisms to anti-EGFR therapy in RAS/RAF wildtype colorectal cancer varies by regimen and line of therapy
Published in Journal of clinical oncology (01-06-2022)“…3554 Background: The conventional theory for the development of treatment resistance to anti-EGFR for metastatic colorectal cancer (mCRC) is the selective…”
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6
Abstract 1972: CXCR5-CXCL13 signaling contributes to CLL relapse and patient survival
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Chronic Lymphocytic Leukemia (CLL) is characterized by the appearance of mature-appearing B cells in the blood, bone marrow, and secondary lymphoid…”
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7
Clinical significance of CXCR5-CXCL13 signaling in multiple myeloma
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e19517 Background: Multiple myeloma (MM) is characterized by the neoplastic proliferation of plasma cells resulting in monoclonal immunoglobulins…”
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WGCNA identification of CXCL13 and associated genes involved in the Tumor Immune Microenvironment (TIME) of lung adenocarcinoma
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Lung cancer is the second most commonly diagnosed cancer, causing the most cancer-related deaths in the United States. Non-small cell lung cancer…”
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9
Transcriptome network analysis identifies co-expressed CXCL13, CXCR5, and associated genes contributes to the aggressive phenotype of TNBC
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Triple negative breast cancer (TNBC) is an aggressive disease associated with poor prognosis. Currently, there are no targeted therapies for this…”
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10
CXCL13-CXCR5 signaling and its co-expression network are associated with colorectal cancer cell growth and poor prognosis
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract The heterogeneity of colorectal cancer (CRC) and its microenvironment has molecular traits of immune cells, and is driven by dysregulated WNT,…”
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Abstract LB-132: The role of CXCL13, its sole receptor CXCR5, and associated genes in multiple myeloma progression
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Multiple myeloma (MM) is characterized by the neoplastic proliferation of plasma cells producing monoclonal immunoglobulin in blood, bone marrow, and…”
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12
P311 Modulates Adipocyte Development
Published in The FASEB journal (01-04-2018)“…Adipogenesis is a complex process of adipocytes formed from progenitor cells that involves changes in gene expression, cell morphology and hormone sensitivity…”
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13
Multivariate analysis of genes expressed in the colorectal tumor immune microenvironment driven by CXCL13
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Colorectal cancer (CRC) is a heterogenous disease having numerous molecular phenotypes. Key tumor progression markers such as microsatellite…”
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14
Multivariate Transcriptome Analysis of CXCR5-CXCL13 signaling in Unmutated and Mutated CLL
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Chronic Lymphocytic Leukemia (CLL) is characterized by the appearance of mature-appearing B cells in the blood, bone marrow, and lymph nodes, but the…”
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15
Multivariate Gene Expression Analysis Identifies Novel Signatures and Therapeutic Targets for CLL Relapse
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Chronic Lymphocytic Leukemia (CLL) is a hematological malignancy of immature B cells that is characterized by episodes of relapse. CLL relapse is…”
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16
Weighted Gene Co-expression Network Analysis of CXCL13, CXCR5, and associated genes in multiple myeloma
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Multiple myeloma (MM) is characterized by the neoplastic proliferation of plasma cells. In 2018, there were approximately 30,770 new cases diagnosed…”
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Abstract 2285: Co-expressed gene networks in CRC CMS1 subtype
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Colorectal cancer (CRC) is a heterogenous disease driven by dysregulated Wnt, Ras-Raf-MAPK, TGF-β, and PI3K-Akt signaling, which leads to an…”
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18
Abstract B046: A novel adjuvant for the treatment of obesity-related cancers
Published in Molecular cancer therapeutics (01-01-2018)“…Abstract Obesity is pandemic and linked to higher incidence and poorer prognosis of several cancers, including pancreatic cancer (PC), triple-negative breast…”
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Abstract 2950: Coexpression networks of miRNAs and gene transcripts coinciding with lung adenocarcinoma progression and survival
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Lung & bronchus cancer is the second most diagnosed cancer, causing the most cancer-related deaths in the United States. A lung and bronchus subtype,…”
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The Role of RBP-Jk in Leptin-Induction of Breast Cancer Progression and Chemoresistance
Published 2017“…In cancer tissues leptin and its receptor, OB-R, are significantly overexpressed, where Notch signaling is altered. In obese individuals, leptin levels are…”
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