Search Results - "Nunes, Sofia C."

Glutathione in Ovarian Cancer: A Double-Edged Sword by Nunes, Sofia C, Serpa, Jacinta

“…Glutathione (GSH) has several roles in a cell, such as a reactive oxygen species (ROS) scavenger, an intervenient in xenobiotics metabolism and a reservoir of…”
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Cysteine Aminotransferase (CAT): A Pivotal Sponsor in Metabolic Remodeling and an Ally of 3-Mercaptopyruvate Sulfurtransferase (MST) in Cancer by Hipólito, Ana, Nunes, Sofia C, Vicente, João B, Serpa, Jacinta

“…Metabolic remodeling is a critical skill of malignant cells, allowing their survival and spread. The metabolic dynamics and adaptation capacity of cancer cells…”
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Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity by Nunes, Sofia C., Ramos, Cristiano, Lopes-Coelho, Filipa, Sequeira, Catarina O., Silva, Fernanda, Gouveia-Fernandes, Sofia, Rodrigues, Armanda, Guimarães, António, Silveira, Margarida, Abreu, Sofia, Santo, Vítor E., Brito, Catarina, Félix, Ana, Pereira, Sofia A., Serpa, Jacinta

“…Ovarian cancer is the second most common gynaecologic malignancy and the main cause of death from gynaecologic cancer, due to late diagnosis and…”
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Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer by Nunes, Sofia C, Lopes-Coelho, Filipa, Gouveia-Fernandes, Sofia, Ramos, Cristiano, Pereira, Sofia A, Serpa, Jacinta

“…BACKGROUNDOvarian cancer is the second most common gynaecologic malignancy and the most common cause of death from gynaecologic cancer, especially due to…”
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Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation by Santos, Inês, Ramos, Cristiano, Mendes, Cindy, Sequeira, Catarina O, Tomé, Catarina S, Fernandes, Dalila G H, Mota, Pedro, Pires, Rita F, Urso, Donato, Hipólito, Ana, Antunes, Alexandra M M, Vicente, João B, Pereira, Sofia A, Bonifácio, Vasco D B, Nunes, Sofia C, Serpa, Jacinta

“…Ovarian cancer is the main cause of death from gynecological cancer, with its poor prognosis mainly related to late diagnosis and chemoresistance (acquired or…”
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Peripheral Blood Serum NMR Metabolomics Is a Powerful Tool to Discriminate Benign and Malignant Ovarian Tumors by Nunes, Sofia C, Sousa, Joana, Silva, Fernanda, Silveira, Margarida, Guimarães, António, Serpa, Jacinta, Félix, Ana, Gonçalves, Luís G

“…Ovarian cancer is the major cause of death from gynecological cancer and the third most common gynecological malignancy worldwide. Despite a slight improvement…”
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Polyurea Dendrimer Folate-Targeted Nanodelivery of l-Buthionine sulfoximine as a Tool to Tackle Ovarian Cancer Chemoresistance by Cruz, Adriana, Mota, Pedro, Ramos, Cristiano, Pires, Rita F, Mendes, Cindy, Silva, José P, Nunes, Sofia C, Bonifácio, Vasco D B, Serpa, Jacinta

“…Ovarian cancer is a highly lethal disease, mainly due to chemoresistance. Our previous studies on metabolic remodeling in ovarian cancer have supported that…”
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Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming by Nunes, Sofia C, Ramos, Cristiano, Santos, Inês, Mendes, Cindy, Silva, Fernanda, Vicente, João B, Pereira, Sofia A, Félix, Ana, Gonçalves, Luís G, Serpa, Jacinta

“…Among gynecologic malignancies, ovarian cancer is the third most prevalent and the most common cause of death, especially due to diagnosis at an advanced stage…”
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Tumor Microenvironment - Selective Pressures Boosting Cancer Progression by Nunes, Sofia C

“…In 2018, 9.6 million deaths from cancer were estimated, being this disease the second leading cause of death worldwide. Notwithstanding all the efforts…”
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Wnt Signaling: Paths for Cancer Progression by Carreira-Barbosa, Filipa, Nunes, Sofia C

“…The Wnt signaling pathways are well known for having several pivotal roles during embryonic development. However, the same developmental signaling pathways…”
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Exploiting Cancer Cells Metabolic Adaptability to Enhance Therapy Response in Cancer by Nunes, Sofia C

“…Despite all the progresses developed in prevention and new treatment approaches, cancer is the second leading cause of death worldwide, being chemoresistance a…”
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Recycling the Interspecific Relations with Epithelial Cells: Bacteria and Cancer Metabolic Symbiosis by Nunes, Sofia C, Serpa, Jacinta

“…Several aspects of the human physiology are controlled by the microbiota that plays a key role in health and disease. In fact, microbial dysbiosis is…”
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Cysteine boosters the evolutionary adaptation to CoCl 2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer by Nunes, Sofia C, Lopes-Coelho, Filipa, Gouveia-Fernandes, Sofia, Ramos, Cristiano, Pereira, Sofia A, Serpa, Jacinta

“…Ovarian cancer is the second most common gynaecologic malignancy and the most common cause of death from gynaecologic cancer, especially due to diagnosis at an…”
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