Search Results - "Nunes, Estevao"

Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results by Pan, Hongchao, Peto, Richard, Henao-Restrepo, Ana-Maria, Preziosi, Marie-Pierre, Sathiyamoorthy, Vasee, Abdool Karim, Quarraisha, Alejandria, Marissa M, Hernández García, César, Kieny, Marie-Paule, Malekzadeh, Reza, Murthy, Srinivas, Reddy, K Srinath, Roses Periago, Mirta, Abi Hanna, Pierre, Ader, Florence, Al-Bader, Abdullah M, Alhasawi, Almonther, Allum, Emma, Alotaibi, Athari, Alvarez-Moreno, Carlos A, Appadoo, Sheila, Asiri, Abdullah, Aukrust, Pål, Barratt-Due, Andreas, Bellani, Samir, Branca, Mattia, Cappel-Porter, Heike B C, Cerrato, Nery, Chow, Ting S, Como, Najada, Eustace, Joe, García, Patricia J, Godbole, Sheela, Gotuzzo, Eduardo, Griskevicius, Laimonas, Hamra, Rasha, Hassan, Mariam, Hassany, Mohamed, Hutton, David, Irmansyah, Irmansyah, Jancoriene, Ligita, Kirwan, Jana, Kumar, Suresh, Lennon, Peter, Lopardo, Gustavo, Lydon, Patrick, Magrini, Nicola, Maguire, Teresa, Manevska, Suzana, Manuel, Oriol, McGinty, Sibylle, Medina, Marco T, Mesa Rubio, María L, Miranda-Montoya, Maria C, Nel, Jeremy, Nunes, Estevao P, Perola, Markus, Portolés, Antonio, Rasmin, Menaldi R, Raza, Aun, Rees, Helen, Reges, Paula P S, Rogers, Chris A, Salami, Kolawole, Salvadori, Marina I, Sinani, Narvina, Sterne, Jonathan A C, Stevanovikj, Milena, Tacconelli, Evelina, Tikkinen, Kari A O, Trelle, Sven, Zaid, Hala, Røttingen, John-Arne, Swaminathan, Soumya

“…The authors report interim results of the WHO Solidarity trial of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon…”
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The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication by Sacramento, Carolina Q., de Melo, Gabrielle R., de Freitas, Caroline S., Rocha, Natasha, Hoelz, Lucas Villas Bôas, Miranda, Milene, Fintelman-Rodrigues, Natalia, Marttorelli, Andressa, Ferreira, André C., Barbosa-Lima, Giselle, Abrantes, Juliana L., Vieira, Yasmine Rangel, Bastos, Mônica M., de Mello Volotão, Eduardo, Nunes, Estevão Portela, Tschoeke, Diogo A., Leomil, Luciana, Loiola, Erick Correia, Trindade, Pablo, Rehen, Stevens K., Bozza, Fernando A., Bozza, Patrícia T., Boechat, Nubia, Thompson, Fabiano L., de Filippis, Ana M. B., Brüning, Karin, Souza, Thiago Moreno L.

“…Zika virus (ZIKV) is a member of the Flaviviridae family, along with other agents of clinical significance such as dengue (DENV) and hepatitis C (HCV) viruses…”
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Effectiveness of direct‐acting agents for hepatitis C and liver stiffness changing after sustained virological response by Fernandes, Flavia F, Piedade, Juliana, Guimaraes, Livia, Nunes, Estevao P, Chaves, Ursula, Goldenzon, Rafaela V, Cardoso, Sandra W, Duarte, Joana, Grinsztejn, Beatriz, Veloso, Valdilea G, Pereira, Gustavo, Perazzo, Hugo

“…Background and Aim Few studies have evaluated sustained virological response (SVR) rates by direct‐acting agents (DAAs) and liver stiffness measurement (LSM)…”
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A Cluster of Diutina catenulata Funguria in Patients with Coronavirus Disease 2019 (COVID-19) Hospitalized in a Tertiary Reference Hospital from Rio de Janeiro, Brazil by Almeida-Paes, Rodrigo, Teixeira, Marcus de Melo, Oliveira, Fernanda Alves de, Almeida, Marcos de Abreu, Almeida-Silva, Fernando, Geraldo, Kim Mattos, Nunes, Estevão Portela, Baker, Bridget M., Stajich, Jason E., Grinsztejn, Beatriz, Veloso, Valdilea Gonçalves, Freitas, Andrea d’Avila, Zancopé-Oliveira, Rosely Maria

“…During the COVID-19 pandemic, fungal infections, especially pulmonary aspergillosis, mucormycosis, and invasive candidiasis, have emerged as a significant…”
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Exploring the Resurgence of a Neglected Disease: Lessons From the 2023-2024 Mpox Outbreak in Rio de Janeiro, Brazil by Silva, Mayara Secco Torres, Coutinho, Carolina, Torres, Thiago Silva, Magalhães, Monica Avelar, Yanavich, Carolyn, Echeverría-Guevara, Amanda, Bastos, Matheus Oliveira, Martins, Pedro Silva, Mesquita, Maira Braga, Reges, Paula Pereira de Souza, Meneguetti, Maria Roberta, Santana, Ana Paula Lovetro, Terra, Marcela, Nunes, Estevão Portela, Lessa, Flavia Cristina Serrão, Moreira, Ronaldo Ismério, Peixoto, Eduardo Mesquita, Paulo, Karolyne Wolch de Almeida, Sant'Ana, Andryelle Cristina, Elias da Silva, Edson, Cardoso, Sandra Wagner, Veloso, Valdilea Gonçalves, Grinsztejn, Beatriz

“…Following the 2022 global mpox outbreak, diagnoses decreased worldwide, even in settings with limited vaccine access. In 2023-2024, a new outbreak emerged in…”
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A minimal monitoring approach for the treatment of hepatitis C virus infection (ACTG A5360 [MINMON]): a phase 4, open-label, single-arm trial by Solomon, Sunil S, Wagner-Cardoso, Sandra, Smeaton, Laura, Sowah, Leonard A, Wimbish, Chanelle, Robbins, Gregory, Brates, Irena, Scello, Christine, Son, Annie, Avihingsanon, Anchalee, Linas, Benjamin, Anthony, Donald, Nunes, Estevão Portela, Kliemann, Dimas A, Supparatpinyo, Khuanchai, Kityo, Cissy, Tebas, Pablo, Bennet, Jaclyn Ann, Santana-Bagur, Jorge, Benson, Constance A, Van Schalkwyk, Marije, Cheinquer, Nelson, Naggie, Susanna, Wyles, David, Sulkowski, Mark

“…Despite widespread availability of direct-acting antivirals including generic formulations, limited progress has been made in the global adoption of hepatitis…”
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The difficult management of disseminated Sporothrix brasiliensis in a patient with advanced AIDS by Paixão, Ariane Gomes, Galhardo, Maria Clara Gutierrez, Almeida-Paes, Rodrigo, Nunes, Estevão Portela, Gonçalves, Marcelo Luiz Carvalho, Chequer, Gisele Larias, Lamas, Cristiane da Cruz

“…Sporotrichosis is an infection caused by a dimorphic fungus of the Sporothrix schenckii complex. Host immunity is an important factor in the clinical…”
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Epidemiological-clinical profile and mortality in patients coinfected with Trypanosoma cruzi/HIV: experience from a Brazilian reference center by Hasslocher-Moreno, Alejandro Marcel, Sousa, Andréa Silvestre de, Xavier, Sergio Salles, Mendes, Fernanda de Souza Nogueira Sardinha, Nunes, Estevão Portela, Grinsztejn, Beatriz Gilda Jegerhorn, Mediano, Mauro Felippe Felix

“…BACKGROUNDThe recent urbanization of Chagas disease (CD) has contributed to a greater risk of coexistence with human immunodeficiency virus (HIV) and AIDS…”
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Ambulatory and hospitalized patients with suspected and confirmed mpox: an observational cohort study from Brazil by Silva, Mayara Secco Torres, Coutinho, Carolina, Torres, Thiago Silva, Peixoto, Eduardo, Ismério, Ronaldo, Lessa, Flavia, Nunes, Estevão Portela, Hoagland, Brenda, Echeverria Guevara, Amanda Dolores, Bastos, Matheus Oliveira, Ferreira Tavares, Isabel Cristina, Diniz Ribeiro, Maria Pia, Meneguetti Seravalli Ramos, Maria Roberta, Andrade, Hugo Boechat, Lovetro Santana, Ana Paula, Santini-Oliveira, Marilia, Santos Netto, Juliana Barbosa, Reges, Paula, Magalhães, Monica Avelar, Silva Rosadas, Leonardo Azevedo, Nazer, Sandro, Velasque, Luciane, Cardoso, Sandra Wagner, da Silva, Edson Elias, Veloso, Valdilea Gonçalves, Wakimoto, Mayumi Duarte, Grinsztejn, Beatriz, Japiassu, André Miguel, Trepow, Marcel, Ferreira, Italo Guariz, Villela, Larissa, Fraga, Rafael Teixeira, Castro de Souza Pires, Mariah, Otavio da Silva Escada, Rodrigo, Paiva de Sousa, Leonardo, Umaña Robleda, Gabriela Lisseth, Santos, Desirée Vieira, Siqueira Camacho, Luiz Ricardo, Amparo, Pedro, Jaegger de França, João Victor, de Oliveira Heluy Correa, Felipe, Costa de Sousa, Bruno Ivanovinsky, Vicari do Valle, Bernardo, Bortot Soares, João Paulo, Fonseca Ferreira, Livia Cristina, da Silva Martins, Pedro, Mesquita, Maira Braga, Hildebrant Coutinho, José Ricardo, de Moraes Perlingeiro, Raissa, Peixoto de Castro Oliveira, Priscila, Pedroso Barbosa, Hugo Perazzo, Accetta, André Figueiredo, Cunha, Marcelo, Eiras, Rosangela Vieira, Martins dos Santos, Ticiana, Davila da Silva, Wladmyr, Silveira, Monique do Vale, de Souza Brum, Tania, Calvet, Guilherme Amaral, Menezes, Rodrigo Caldas, Pereira, Sandro Antônio

“…By October 30, 2022, 76,871 cases of mpox were reported worldwide, with 20,614 cases in Latin America. This study reports characteristics of a case series of…”
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Cryptococcal antigenemia prevalence and clinical data in HIV‐infected patients from the reference centre at INI‐FIOCRUZ, Rio de Janeiro, Southeast of Brazil by Ferreira, Marcela de F., Brito‐Santos, Fabio, Trilles, Luciana, Almeida, Marcos A., Wanke, Bodo, Veloso, Valdilea G., Nunes, Estevao P., Lazera, Marcia dos S.

“…Summary Cryptococcal meningitis is a several disease common in late stage of HIV infection. Detection of cryptococcal antigen (CrAg) is an important for early…”
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Prevalence of baseline NS3 resistance-associated substitutions (RASs) on treatment with protease inhibitors in patients infected with HCV genotype 1 by Costa, Vanessa Duarte, Delvaux, Nathália, Brandão-Mello, Carlos Eduardo, Nunes, Estevão Portela, de Sousa, Paulo Sérgio Fonseca, de Souza Rodrigues, Lia Laura Lewis Ximenez, Lampe, Elisabeth, do Amaral Mello, Francisco Campello

“…Treatment for hepatitis C has evolved significantly with the licensing of direct-acting antiviral drugs (DAAs). However, one of the limiting factors of the…”
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Sporothrix schenckii meningitis in AIDS during immune reconstitution syndrome by Galhardo, Maria Clara Gutierrez, Silva, Marcus Tulius T, Lima, Marco Antonio, Nunes, Estevão Portela, Schettini, Luiz Eduardo C, de Freitas, Rodrigo Fernandes, de Almeida Paes, Rodrigo, Neves, Elizabeth de Sousa, do Valle, Antonio Carlos Francesconi

“…Sporotrichosis is a fungal disease usually restricted to the cutaneous and lymphatic systems. Visceral involvement is unusual. To date, only 21 cases of…”
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The DART Trial: 'The Doctor's Dilemma' revisited by NUNES, Estevão Portela, GRINSZTEJN, Beatriz, SCHECHTER, Mauro

“…Treatment of HIV infection in developing countries, particularly those in Africa, is still a major challenge to healthcare systems with limited laboratory…”
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Liver stiffness regression after sustained virological response by direct-acting antivirals reduces the risk of outcomes by Piedade, Juliana, Pereira, Gustavo, Guimarães, Lívia, Duarte, Joana, Victor, Lívia, Baldin, Caroline, Inacio, Cintia, Santos, Ricardo, Chaves, Úrsula, Nunes, Estevão P., Grinsztejn, Beatriz, Veloso, Valdilea G., Fernandes, Flavia, Perazzo, Hugo

“…The role of liver stiffness measurement (LSM) after sustained virological response (SVR) in HCV patients treated by direct-acting antivirals (DAAs) remains…”
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Predictive factors associated with liver fibrosis and steatosis by transient elastography in patients with HIV mono‐infection under long‐term combined antiretroviral therapy by Perazzo, Hugo, Cardoso, Sandra W, Yanavich, Carolyn, Nunes, Estevão P, Morata, Michelle, Gorni, Nathalia, Silva, Paula Simplicio, Cardoso, Claudia, Almeida, Cristiane, Luz, Paula, Veloso, Valdilea G, Grinsztejn, Beatriz

“…Introduction Non‐alcoholic fatty liver disease is characterized by the presence of hepatic steatosis and can be associated with fibrosis progression,…”
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Treatment of chronic HCV infection with DAAs in Rio de Janeiro/Brazil: SVR rates and baseline resistance analyses in NS5A and NS5B genes by Costa, Vanessa D, Brandão-Mello, Carlos E, Nunes, Estevão P, Dos Santos Silva, Pedro Guilherme Corôa, de Souza Rodrigues, Lia Laura Lewis Ximenez, Lampe, Elisabeth, do Amaral Mello, Francisco Campello

“…The selection of viral strains with resistance-associated substitutions at hepatitis C virus (HCV) NS5A and NS5B genes is considered one of the limiting…”
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Monotherapy with lopinavir/ritonavir by Schechter, Mauro, Nunes, Estevão Portela

“…Despite the unprecedented pace of development of drugs for the treatment of a viral disease and the unquestionable efficacy of antiretroviral therapy, there is…”
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Mpox severity and associated hospitalizations among people with HIV and related immunosuppression in Brazil by Silva, Mayara S T, Coutinho, Carolina, Torres, Thiago S, Peixoto, Eduardo M, Bastos, Matheus O, Mesquita, Maira B, Tavares, Isabel C F, Andrade, Hugo B, Reges, Paula P S, Martins, Pedro S, Echeverría-Guevara, Amanda, Moreira, Ronaldo I, Lessa, Flavia Cristina S, Hoagland, Brenda, Nunes, Estevão P, Cardoso, Sandra W, Veloso, Valdilea G, Grinsztejn, Beatriz

“…This study aimed to analyze characteristics of mpox hospitalization in a Brazilian cohort, further exploring the impact of HIV on mpox-related outcomes and…”
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Changing mortality profile among HIV-infected patients in Rio de Janeiro, Brazil: shifting from AIDS to non-AIDS related conditions in the HAART era by Grinsztejn, Beatriz, Luz, Paula M, Pacheco, Antonio G, Santos, Desiree V G, Velasque, Luciane, Moreira, Ronaldo I, Guimarães, Maria Regina C, Nunes, Estevão P, Lemos, Alberto S, Ribeiro, Sayonara R, Campos, Dayse P, Vitoria, Marco A A, Veloso, Valdilea G

“…We describe temporal trends in the mortality rates and factors associated with AIDS and non-AIDS related mortality at the Evandro Chagas Clinical Research…”
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Sepsis is a major determinant of outcome in critically ill HIV/AIDS patients by Japiassú, André M, Amâncio, Rodrigo T, Mesquita, Emerson C, Medeiros, Denise M, Bernal, Helena B, Nunes, Estevão P, Luz, Paula M, Grinsztejn, Beatriz, Bozza, Fernando A

“…New challenges have arisen for the management of critically ill HIV/AIDS patients. Severe sepsis has emerged as a common cause of intensive care unit (ICU)…”
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