Search Results - "Nunes, Bruno T.D"

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    Using Next Generation Sequencing to Study the Genetic Diversity of Candidate Live Attenuated Zika Vaccines by Collins, Natalie D, Shan, Chao, Nunes, Bruno T D, Widen, Steven G, Shi, Pei-Yong, Barrett, Alan D T, Sarathy, Vanessa V

    Published in Vaccines (Basel) (03-04-2020)
    “…(ZIKV) is a mosquito-transmitted positive-sense RNA virus in the family . Candidate live-attenuated vaccine (LAV) viruses with engineered deletions in the 3'…”
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    Journal Article
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    A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models by Shan, Chao, Muruato, Antonio E, Nunes, Bruno T D, Luo, Huanle, Xie, Xuping, Medeiros, Daniele B A, Wakamiya, Maki, Tesh, Robert B, Barrett, Alan D, Wang, Tian, Weaver, Scott C, Vasconcelos, Pedro F C, Rossi, Shannan L, Shi, Pei-Yong

    Published in Nature medicine (01-06-2017)
    “…Pei-Yong Shi and colleagues report that a deletion mutant of Zika virus is safe and effective as a live-attenuated vaccine in mice and induces sterilizing…”
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    Journal Article
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    An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction by Xia, Hongjie, Luo, Huanle, Shan, Chao, Muruato, Antonio E., Nunes, Bruno T. D., Medeiros, Daniele B. A., Zou, Jing, Xie, Xuping, Giraldo, Maria Isabel, Vasconcelos, Pedro F. C., Weaver, Scott C., Wang, Tian, Rajsbaum, Ricardo, Shi, Pei-Yong

    Published in Nature communications (29-01-2018)
    “…Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus (ZIKV), responsible for the recent epidemics, has fixed a mutation in…”
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    Role of mutational reversions and fitness restoration in Zika virus spread to the Americas by Liu, Jianying, Liu, Yang, Shan, Chao, Nunes, Bruno T. D., Yun, Ruimei, Haller, Sherry L., Rafael, Grace H., Azar, Sasha R., Andersen, Clark R., Plante, Kenneth, Vasilakis, Nikos, Shi, Pei-Yong, Weaver, Scott C.

    Published in Nature communications (26-01-2021)
    “…Zika virus (ZIKV) emerged from obscurity in 2013 to spread from Asia to the South Pacific and the Americas, where millions of people were infected, accompanied…”
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    Understanding Zika Virus Stability and Developing a Chimeric Vaccine through Functional Analysis by Xie, Xuping, Yang, Yujiao, Muruato, Antonio E, Zou, Jing, Shan, Chao, Nunes, Bruno T D, Medeiros, Daniele B A, Vasconcelos, Pedro F C, Weaver, Scott C, Rossi, Shannan L, Shi, Pei-Yong

    Published in mBio (07-02-2017)
    “…Compared with other flaviviruses, Zika virus (ZIKV) is uniquely associated with congenital diseases in pregnant women. One recent study reported that (i) ZIKV…”
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    Zika structural genes determine the virulence of African and Asian lineages by Nunes, Bruno T. D., Fontes-Garfias, Camila R., Shan, Chao, Muruato, Antonio E., Nunes, Jannyce G. C., Burbano, Rommel M. R., Vasconcelos, Pedro F. C., Shi, Pei-Yong, Medeiros, Daniele B. A.

    Published in Emerging microbes & infections (01-01-2020)
    “…The Asian lineage of Zika virus (ZIKV) is responsible for the recent epidemics in the Americas and severe disease, whereas the African lineage of ZIKV has not…”
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    Journal Article
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