Search Results - "Nunes, Bruno T.D"
-
1
East/Central/South African genotype chikungunya virus, Brazil, 2014
Published in Emerging infectious diseases (01-05-2015)Get full text
Journal Article -
2
Zika virus epidemic in Brazil. I. Fatal disease in adults: clinical and laboratorial aspects
Published in Journal of clinical virology (01-12-2016)“…Highlights • Zika virus in persons with immunologic disorders can result in severe disease and deaths. • In patients with immune suppression and/or autoimmune…”
Get full text
Journal Article -
3
Using Next Generation Sequencing to Study the Genetic Diversity of Candidate Live Attenuated Zika Vaccines
Published in Vaccines (Basel) (03-04-2020)“…(ZIKV) is a mosquito-transmitted positive-sense RNA virus in the family . Candidate live-attenuated vaccine (LAV) viruses with engineered deletions in the 3'…”
Get full text
Journal Article -
4
A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models
Published in Nature medicine (01-06-2017)“…Pei-Yong Shi and colleagues report that a deletion mutant of Zika virus is safe and effective as a live-attenuated vaccine in mice and induces sterilizing…”
Get full text
Journal Article -
5
An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
Published in Nature communications (29-01-2018)“…Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus (ZIKV), responsible for the recent epidemics, has fixed a mutation in…”
Get full text
Journal Article -
6
Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease
Published in Cell (13-07-2017)“…The emergence of Zika virus (ZIKV) and its association with congenital malformations has prompted the rapid development of vaccines. Although efficacy with…”
Get full text
Journal Article -
7
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
Published in Nature communications (22-09-2017)“…Zika virus infection during pregnancy can cause congenital abnormities or fetal demise. The persistence of Zika virus in the male reproductive system poses a…”
Get full text
Journal Article -
8
Role of mutational reversions and fitness restoration in Zika virus spread to the Americas
Published in Nature communications (26-01-2021)“…Zika virus (ZIKV) emerged from obscurity in 2013 to spread from Asia to the South Pacific and the Americas, where millions of people were infected, accompanied…”
Get full text
Journal Article -
9
A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission
Published in Cell host & microbe (10-10-2018)“…Zika virus (ZIKV) infection of the mother during pregnancy causes devastating Zika congenital syndrome in the offspring. A ZIKV vaccine with optimal safety and…”
Get full text
Journal Article -
10
Understanding Zika Virus Stability and Developing a Chimeric Vaccine through Functional Analysis
Published in mBio (07-02-2017)“…Compared with other flaviviruses, Zika virus (ZIKV) is uniquely associated with congenital diseases in pregnant women. One recent study reported that (i) ZIKV…”
Get full text
Journal Article -
11
Zika structural genes determine the virulence of African and Asian lineages
Published in Emerging microbes & infections (01-01-2020)“…The Asian lineage of Zika virus (ZIKV) is responsible for the recent epidemics in the Americas and severe disease, whereas the African lineage of ZIKV has not…”
Get full text
Journal Article -
12
The Usefulness of a Duplex RT-qPCR during the Recent Yellow Fever Brazilian Epidemic: Surveillance of Vaccine Adverse Events, Epizootics and Vectors
Published in Pathogens (Basel) (03-06-2021)“…From 2016 to 2018, Brazil faced the biggest yellow fever (YF) outbreak in the last 80 years, representing a risk of YF reurbanization, especially in…”
Get full text
Journal Article -
13
Zika Virus Epidemic in Brazil. II. Post-Mortem Analyses of Neonates with Microcephaly, Stillbirths, and Miscarriage
Published in Journal of clinical medicine (28-11-2018)“…The recent Zika virus(ZIKV) epidemic in Brazil was characterized by a range of different clinical presentations, particularly microcephaly, Guillain-Barré…”
Get full text
Journal Article -
14
Zika virus epidemic in Brazil. I. Fatal disease in adults: Clinical andlaboratorial aspects
Published in Journal of clinical virology (05-11-2016)Get full text
Journal Article -
15
Reporter Virus Neutralization Test Evaluation for Dengue and Zika Virus Diagnosis in Flavivirus Endemic Area
Published in Pathogens (Basel) (03-07-2021)“…Reporter virus neutralization test (RVNT) has been used as an alternative to the more laborious and time-demanding conventional PRNT assay for both DENV and…”
Get full text
Journal Article