Search Results - "Nukala, Ujwani"

Mathematical model of a personalized neoantigen cancer vaccine and the human immune system by Rodriguez Messan, Marisabel, Yogurtcu, Osman N, McGill, Joseph R, Nukala, Ujwani, Sauna, Zuben E, Yang, Hong

“…Cancer vaccines are an important component of the cancer immunotherapy toolkit enhancing immune response to malignant cells by activating CD4+ and CD8+ T…”
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Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects by Shrum, Stephen A, Nukala, Ujwani, Shrimali, Shivangi, Pineda, Edith Nathalie, Krager, Kimberly J, Thakkar, Shraddha, Jones, Darin E, Pathak, Rupak, Breen, Philip J, Aykin-Burns, Nukhet, Compadre, Cesar M

“…Tocotrienols have powerful radioprotective properties in multiple organ systems and are promising candidates for development as clinically effective radiation…”
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Antioxidant Tocols as Radiation Countermeasures (Challenges to be Addressed to Use Tocols as Radiation Countermeasures in Humans) by Nukala, Ujwani, Thakkar, Shraddha, Krager, Kimberly J, Breen, Philip J, Compadre, Cesar M, Aykin-Burns, Nukhet

“…Radiation countermeasures fall under three categories, radiation protectors, radiation mitigators, and radiation therapeutics. Radiation protectors are agents…”
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Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine by Valega-Mackenzie, Wencel, Rodriguez Messan, Marisabel, Yogurtcu, Osman N., Nukala, Ujwani, Sauna, Zuben E., Yang, Hong, Wallqvist, ed., Anders

“…The advancements in next-generation sequencing have made it possible to effectively detect somatic mutations, which has led to the development of personalized…”
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A Systematic Review of the Efforts and Hindrances of Modeling and Simulation of CAR T-cell Therapy by Nukala, Ujwani, Rodriguez Messan, Marisabel, Yogurtcu, Osman N., Wang, Xiaofei, Yang, Hong

“…Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy that has recently become highly instrumental in the fight against life-threatening diseases…”
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Analysis of tumor-immune functional responses in a mathematical model of neoantigen cancer vaccines by Han, Lifeng, Rodriguez Messan, Marisabel, Yogurtcu, Osman N., Nukala, Ujwani, Yang, Hong

“…Not provided…”
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Analysis of tumor-immune functional responses in a mathematical model of neoantigen cancer vaccines by Han, Lifeng, Rodriguez Messan, Marisabel, Yogurtcu, Osman N., Nukala, Ujwani, Yang, Hong

“…Cancer neoantigen vaccines have emerged as a promising approach to stimulating the immune system to fight cancer. We propose a simple model including key…”
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Mathematical model of a personalized neoantigen cancer vaccine and the human immune system by Rodriguez Messan, Marisabel, Yogurtcu, Osman N., McGill, Joseph R., Nukala, Ujwani, Sauna, Zuben E., Yang, Hong, Csikász-Nagy, Attila

“…Cancer vaccines are an important component of the cancer immunotherapy toolkit enhancing immune response to malignant cells by activating CD4+and CD8+T cells…”
Get full text

Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine by Valega-Mackenzie, Wencel, Rodriguez Messan, Marisabel, Yogurtcu, Osman N, Nukala, Ujwani, Sauna, Zuben E, Yang, Hong

“…The advancements in next-generation sequencing have made it possible to effectively detect somatic mutations, which has led to the development of personalized…”
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Dosage optimization for reducing tumor burden using a phenotype-structured population model with a drug-resistance continuum by Han, Lifeng, Yogurtcu, Osman N, Rodriguez Messan, Marisabel, Valega-Mackenzie, Wencel, Nukala, Ujwani, Yang, Hong

“…Drug resistance is a significant obstacle to effective cancer treatment. To gain insights into how drug resistance develops, we adopted a concept called…”
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A Retrospective Review of Center for Biologics Evaluation and Research Advisory Committee Meetings in the Context of the FDA’s Benefit-Risk Framework by Mutanga, Jane Namangolwa, Nukala, Ujwani, Rodriguez Messan, Marisabel, Yogurtcu, Osman N., McCormick, Quinn, Sauna, Zuben E., Whitaker, Barbee I., Forshee, Richard A., Yang, Hong

“…The US FDA Center for Biologics Evaluation and Research (CBER) is responsible for the regulation of biologically derived products. FDA has established Advisory…”
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Understanding The Differences in The Radioprotection Activity of The Vitamin E Tocols, and Their Implications in Developing Effective Radioprotectors by Nukala, Ujwani

“…With the increased use of ionizing radiation for various purposes like radiotherapy, nuclear power generation, sterilization, the likelihood of intentional or…”
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A Systematic Review of the Efforts and Hindrances of Modeling and Simulation of CAR T-cell Therapy by Nukala, Ujwani, Messan, Marisabel Rodriguez, Yogurtcu, Osman N, Wang, Xiaofei, Yang, Hong

“…Chimeric Antigen Receptor (CAR) T-cell therapy is an immunotherapy that has recently become highly instrumental in the fight against life-threatening diseases…”
Get full text