Search Results - "Nuijts, Rudy M. M. A."

Oxidative stress induces dysregulated autophagy in corneal epithelium of keratoconus patients by Shetty, Rohit, Sharma, Anupam, Pahuja, Natasha, Chevour, Priyanka, Padmajan, Neeraja, Dhamodaran, Kamesh, Jayadev, Chaitra, M M A Nuijts, Rudy, Ghosh, Arkasubhra, Nallathambi, Jeyabalan

“…Oxidative stress is one of the key factors that contributes to the pathogenesis of keratoconus (KC). Macroautophagy is a vital cellular mechanism that is…”
Get full text

Clinical Evaluation and Validation of the Dutch Crosslinking for Keratoconus Score by Wisse, Robert P L, Simons, Rob W P, van der Vossen, Martijn J B, Muijzer, Marc B, Soeters, Nienke, Nuijts, Rudy M M A, Godefrooij, Daniel A

“…Defining keratoconus progression is fundamental in clinical decision making because crosslinking treatments are indicated when the disease is considered…”
Get more information

A novel combination of corneal confocal microscopy, clinical features and artificial intelligence for evaluation of ocular surface pain by Kundu, Gairik, Shetty, Rohit, D'Souza, Sharon, Khamar, Pooja, Nuijts, Rudy M. M. A, Sethu, Swaminathan, Roy, Abhijit Sinha

“…Objectives To analyse various corneal nerve parameters using confocal microscopy along with systemic and orthoptic parameters in patients presenting with…”
Get full text

Single cell transcriptomics reveals the heterogeneity of the human cornea to identify novel markers of the limbus and stroma by Català, Pere, Groen, Nathalie, Dehnen, Jasmin A., Soares, Eduardo, van Velthoven, Arianne J. H., Nuijts, Rudy M. M. A., Dickman, Mor M., LaPointe, Vanessa L. S.

“…The cornea is the clear window that lets light into the eye. It is composed of five layers: epithelium, Bowman’s layer, stroma, Descemet’s membrane and…”
Get full text

Keratoconus patients exhibit a distinct ocular surface immune cell and inflammatory profile by D’Souza, Sharon, Nair, Archana Padmanabhan, Sahu, Ganesh Ram, Vaidya, Tanuja, Shetty, Rohit, Khamar, Pooja, Mullick, Ritika, Gupta, Sneha, Dickman, Mor M., Nuijts, Rudy M. M. A., Mohan, Rajiv R., Ghosh, Arkasubhra, Sethu, Swaminathan

“…Inflammatory factors have been considered to contribute to keratoconus (KC) pathogenesis. This study aims to determine the immune cells subsets and soluble…”
Get full text

Pre-analytical sample handling effects on tear fluid protein levels by Gijs, Marlies, Arumugam, Sinthuja, van de Sande, Nienke, Webers, Carroll A. B., Sethu, Swaminathan, Ghosh, Arkasubhra, Shetty, Rohit, Vehof, Jelle, Nuijts, Rudy M. M. A.

“…Tear fluid is emerging as a source of non-invasive biomarkers, both for ocular and systemic conditions. Accurate quantification of tear proteins can be…”
Get full text

Association of tear fluid amyloid and tau levels with disease severity and neurodegeneration by Gijs, Marlies, Ramakers, Inez H. G. B., Visser, Pieter Jelle, Verhey, Frans R. J., van de Waarenburg, Marjo P. H., Schalkwijk, Casper G., Nuijts, Rudy M. M. A., Webers, Carroll A. B.

“…There has been increasing interest in finding non-invasive biomarkers for neurodegenerative diseases such as Alzheimer’s disease (AD). This observational study…”
Get full text

Retrospective assessment of accuracy of nine intraocular lens power calculation formulae in eyes with axial myopia by Shetty, Naren, Shetty, Rohit, Nuijts, Rudy M M A, Satija, Anuj, Roy, Abhijit S, Kaweri, Luci

“…To compare the accuracy of nine conventional and newer-generation formulae in calculating intraocular lens power in eyes with axial myopia. Tertiary eye care…”
Get full text

Comparability of subjective and objective measurements of nuclear density in cataract patients by Makhotkina, Natalia Y., Berendschot, Tos T. J. M., Biggelaar, Frank J. H. M., Weik, Alexander R. H., Nuijts, Rudy M. M. A.

“…Purpose To evaluate the relationship between subjective and objective measurements of lens density and the energy of phacoemulsification. Setting University…”
Get full text

Ocular surface immune cell diversity in dry eye disease by Nair, Archana, D'Souza, Sharon, Khamar, Pooja, Nuijts, Rudy, Sethu, Swaminathan, Shetty, Rohit

“…Dry eye disease (DED) is a multifactorial chronic ocular surface inflammatory condition. Disease severity has been directly related to the immuno-inflammatory…”
Get full text

Evaluation of pre-processing methods for tear fluid proteomics using proximity extension assays by Vergouwen, Daphne P. C., Schotting, Amber J., Endermann, Tanja, van de Werken, Harmen J. G., Grashof, Dwin G. B., Arumugam, Sinthuja, Nuijts, Rudy M. M. A., ten Berge, Josianne C., Rothova, Aniki, Schreurs, Marco W. J., Gijs, Marlies

“…Tear fluid forms a potential source for biomarker identification, and can be minimal invasively collected via Schirmer strips. The lack of knowledge on the…”
Get full text

Repeatability, reproducibility, and agreement of three tonometers for measuring intraocular pressure in rabbits by Bertens, Christian J. F., van Mechelen, Ralph J. S., Berendschot, Tos T. J. M., Gijs, Marlies, Wolters, Jarno E. J., Gorgels, Theo G. M. F., Nuijts, Rudy M. M. A., Beckers, Henny J. M.

“…The aim of this study was to evaluate repeatability, reproducibility, and agreement of three commonly used tonometers in animal research (TonoLab, TonoVet, and…”
Get full text

Tear biomarkers for Alzheimer's disease screening and diagnosis (the TearAD study): design and rationale of an observational longitudinal multicenter study by van de Sande, Nienke, Ramakers, Inez H G B, Visser, Pieter Jelle, Verhey, Frans R J, Verbraak, Frank D, Bouwman, Femke H, Berendschot, Tos T J M, Nuijts, Rudy M M A, Webers, Carroll A B, Gijs, Marlies

“…Alzheimer's disease (AD) is the most common cause of dementia, and due to increasing life expectancy the number of patients is expected to grow. The diagnosis…”
Get full text

Artificial intelligence-based stratification of demographic, ocular surface high-risk factors in progression of keratoconus by Kundu, Gairik, Shetty, Naren, Shetty, Rohit, Khamar, Pooja, D'Souza, Sharon, Meda, Tulasi, Nuijts, Rudy, Narasimhan, Raghav, Roy, Abhijit

“…Purpose: The purpose of this study was to identify and analyze the clinical and ocular surface risk factors influencing the progression of keratoconus (KC)…”
Get full text

Effects of graft thickness and asymmetry on visual gain and aberrations after descemet stripping automated endothelial keratoplasty by Dickman, Mor M, Cheng, Yanny Y Y, Berendschot, Tos T J M, van den Biggelaar, Frank J H M, Nuijts, Rudy M M A

“…Understanding the contribution of graft thickness and asymmetry to visual gain and posterior corneal (PC) higher-order aberrations (HOAs) may assist optimizing…”
Get more information

Type 1-type 2 interferon imbalance in dry eye disease by Panigrahi, Trailokyanath, D'Souza, Sharon, Suresh Babu, Vishnu, Dickman, Mor, Nuijts, Rudy, Sethu, Swaminathan, Shetty, Rohit

“…Purpose: Dry eye disease (DED) is characterized by altered ocular surface proinflammatory and antiinflammatory factors. Interferons (IFNs) are a class of…”
Get full text

New ophthalmologic imaging techniques for detection and monitoring of neurodegenerative changes in diabetes: a systematic review by De Clerck, Eline E B, Dr, Schouten, Jan S A G, MD, Berendschot, Tos T J M, PhD, Kessels, Alfons G H, MD, Nuijts, Rudy M M A, Prof, Beckers, Henny J M, MD, Schram, Miranda T, PhD, Stehouwer, Coen D A, Prof, Webers, Carroll A B, Prof

“…Summary Optical coherence tomography (OCT) of the retina and around the optic nerve head and corneal confocal microscopy (CCM) are non-invasive and repeatable…”
Get full text

Remote follow-up after cataract surgery (CORE-RCT): study protocol of a randomized controlled trial by Claessens, Janneau L J, Wanten, Joukje C, Bauer, Noël J C, Nuijts, Rudy M M A, Findl, Oliver, Huemer, Josef, Imhof, Saskia M, Wisse, Robert P L

“…Cataract surgery has become one of the most performed surgical procedures worldwide. Postoperative management consists of routine clinical examinations to…”
Get full text

Altered Ocular Surface Health Status and Tear Film Immune Profile Due to Prolonged Daily Mask Wear in Health Care Workers by D'Souza, Sharon, Vaidya, Tanuja, Nair, Archana Padmanabhan, Shetty, Rohit, Kumar, Nimisha Rajiv, Bisht, Anadi, Panigrahi, Trailokyanath, J, Tejal S, Khamar, Pooja, Dickman, Mor M, Agrawal, Ruchika, Mahajan, Sanjay, Sengupta, Sneha, Nuijts, Rudy M M A, Sethu, Swaminathan, Ghosh, Arkasubhra

“…Prolonged daily face mask wearing over several months might affect health of the ocular surface and is reported to be associated with complaints of discomfort…”
Get full text

Pharmacokinetics and efficacy of a ketorolac-loaded ocular coil in New Zealand white rabbits by Bertens, Christian J. F., Gijs, Marlies, Dias, Aylvin A. J., van den Biggelaar, Frank J. H. M., Ghosh, Arkasubhra, Sethu, Swaminathan, Nuijts, Rudy M. M. A.

“…Eye drops are considered standard practice for the delivery of ocular drugs. However, low patient compliance and low drug levels compromise its effectiveness…”
Get full text