Search Results - "Nuga, Oluwademilade"

EXTH-06. GLIOBLASTOMA PATIENT SPECIFIC TRANSCRIPTOME REMODELING IN RESPONSE TO MDM2 ANTAGONIST TREATMENT OF WILD-TYPE P53 CANCER STEM CELLS IS ASSOCIATED WITH SENSITIVITY AND STRATEGIES FOR COMBINATION THERAPY by Meng, Yuling, Mughal, Nouman, Datta, Indrani, Nuga, Oluwademilade, Irtenkauf, Susan, Hasselbach, Laura, Quenneville, Kristyn, Brown, Stephen, deCarvalho, Ana

“…Over 70% of glioblastomas are p53 wild-type and these patients could benefit from p53 reactivation treatment. Here we determined the sensitivity of a…”
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Abstract 4742: The influence of cellular developmental state on response to therapeutics in glioblastoma by Nuga, Oluwademilade, deCarvalho, Ana, Ruden, Douglas, Brown, Stephen, Datta, Indrani, Malta, Tathianne

“…Glioblastoma (GBM) is an aggressive tumor treated with ionizing radiation (IR) and temozolomide (TMZ). Here we investigate how developmental state of…”
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EXTH-36. PHARMACEUTICAL INHIBITION OF CYCLIN DEPENDENT KINASE 4/6 (CDK4/6) IN GLIOBLASTOMA by Nuga, Oluwademilade, Meng, Yuling, Berezovsky, Artem, Nelson, Kevin, de Carvalho, Ana

“…Potent and selective CDK4/6 inhibitors (CDK4/6i) have potential for treating glioblastoma. Although genomic abnormalities affecting CDK4/6-RB1 signaling axis,…”
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Abstract 2519: Identification of novel MET fusion transcript amplification in glioblastoma by Nuga, Oluwademilade, deCarvalho, Ana, Meng, Yuling, Hasselbach, Laura, Nelson, Kevin, Irtenkauf, Susan, Transou, Andrea

“…Glioblastoma (GBM) is the most common and aggressive primary CNS malignant tumor with a 15.2% 2 year survival rate for tumors diagnosed between 2008 and 2012…”
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Linear poly-ubiquitin remodels the proteome and influences hundreds of regulators in Drosophila by Nuga, Oluwademilade, Richardson, Kristin, Patel, Nikhil C, Wang, Xusheng, Pagala, Vishwajeeth, Stephan, Anna, Peng, Junmin, Demontis, Fabio, Todi, Sokol V

“…Abstract Ubiquitin controls many cellular processes via its posttranslational conjugation onto substrates. Its use is highly variable due to its ability to…”
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GENE-55. GENE EXPRESSION SIGNATURE ASSOCIATED WITH AGGRESSIVE GLIOBLASTOMA GROWTH IS ENRICHED IN CHROMATIN MODIFICATION AND STEMNESS TRANSCRIPTIONAL REGULATION PROGRAMS by Berezovsky, Artem, Nuga, Oluwademilade, Meng, Yuling, Poisson, Laila, Noushmehr, Houtan, deCarvalho, Ana

“…Abstract Prognosis of patients diagnosed with IDHwt glioblastoma is influenced by known clinical and demographic factors, and likely by physiological…”
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