Search Results - "Nudler, E"

New insights into the mechanism of heat shock response activation by Shamovsky, I, Nudler, E

“…Heat shock (HS) response is a universal mechanism of protection against adverse environmental conditions. It is manifested mainly by rapid and robust induction…”
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The riboswitch control of bacterial metabolism by Nudler, Evgeny, Mironov, Alexander S

“…Aptamers are artificial nucleic acids that selectively bind small molecules. In the past two years, it has become clear that nature has already devised its own…”
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Transcription through the roadblocks: the role of RNA polymerase cooperation by Epshtein, Vitaly, Toulmé, Francine, Rahmouni, A.Rachid, Borukhov, Sergei, Nudler, Evgeny

“…During transcription, cellular RNA polymerases (RNAP) have to deal with numerous potential roadblocks imposed by various DNA binding proteins. Many such…”
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Transcription Processivity: Protein-DNA Interactions Holding Together the Elongation Complex by Nudler, Evgeny, Avetissova, Ekaterina, Markovtsov, Vadim, Goldfarb, Alex

“…The elongation of RNA chains during transcription occurs in a ternary complex containing RNA polymerase (RNAP), DNA template, and nascent RNA. It is shown here…”
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Motion and enzymatic degradation of DNA in the atomic force microscope by Bezanilla, M., Drake, B., Nudler, E., Kashlev, M., Hansma, P.K., Hansma, H.G.

“…The dynamics and enzymatic degradation of single DNA molecules can now be observed with the atomic force microscope. A combination of two advances has made…”
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Cooperation of GroEL/GroES and DnaK/DnaJ Heat Shock Proteins in Preventing Protein Misfolding in Escherichia coli by Gragerov, Alexander, Nudler, Evgeny, Komissarova, Natalia, Gaitanaris, George A., Gottesman, Max E., Nikiforov, Vadim

“…Newly synthesized proteins aggregate extensively in Escherichia coli rpoH mutants, which are deficient in the heat shock proteins (hsp). Overproduction of…”
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Mechanistic model of the elongation complex of Escherichia coli RNA polymerase by Korzheva, N, Mustaev, A, Nudler, E, Nikiforov, V, Goldfarb, A

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NO-Mediated Cytoprotection: Instant Adaptation to Oxidative Stress in Bacteria by Gusarov, Ivan, Nudler, Evgeny, Snyder, Solomon H.

“…Numerous sophisticated systems have been described that protect bacteria from increased levels of reactive oxygen species. Although indispensable during…”
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RNA-mediated response to heat shock in mammalian cells by Nudler, Evgeny, Ivannikov, Maxim, Gershon, David, Shamovsky, Ilya, Kandel, Eugene S

“…The heat-shock transcription factor 1 (HSF1) has an important role in the heat-shock response in vertebrates by inducing the expression of heat-shock proteins…”
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RNA polymerase: the vehicle of transcription by Borukhov, Sergei, Nudler, Evgeny

“…RNA polymerase (RNAP) is the principal enzyme of gene expression and regulation for all three divisions of life: Eukaryota, Archaea and Bacteria. Recent…”
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Cooperation between RNA Polymerase Molecules in Transcription Elongation by Epshtein, Vitaly, Nudler, Evgeny

“…Transcription elongation is responsible for rapid synthesis of RNA chains of thousands of nucleotides in vivo. In contrast, a single round of transcription…”
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S-nitrosylation signaling in Escherichia coli by Gusarov, Ivan, Nudler, Evgeny

“…Most bacteria generate nitric oxide (NO) either aerobically by NO synthases or anaerobically from nitrite. Far from being a mere by-product of nitrate…”
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Control of Intrinsic Transcription Termination by N and NusA: The Basic Mechanisms by Gusarov, Ivan, Nudler, Evgeny

“…Intrinsic transcription termination plays a crucial role in regulating gene expression in prokaryotes. After a short pause, the termination signal appears in…”
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Sensing Small Molecules by Nascent RNA: A Mechanism to Control Transcription in Bacteria by Mironov, Alexander S., Gusarov, Ivan, Rafikov, Ruslan, Lopez, Lubov Errais, Shatalin, Konstantin, Kreneva, Rimma A., Perumov, Daniel A., Nudler, Evgeny

“…Thiamin and riboflavin are precursors of essential coenzymes—thiamin pyrophosphate (TPP) and flavin mononucleotide (FMN)/flavin adenine dinucleotide (FAD),…”
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A Ratchet Mechanism of Transcription Elongation and Its Control by Bar-Nahum, Gil, Epshtein, Vitaly, Ruckenstein, Andrei E., Rafikov, Ruslan, Mustaev, Arkady, Nudler, Evgeny

“…RNA chain elongation is a highly processive and accurate process that is finely regulated by numerous intrinsic and extrinsic signals. Here we describe a…”
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The Mechanism of Intrinsic Transcription Termination by Gusarov, Ivan, Nudler, Evgeny

“…In bacteria, an intrinsic transcription termination signal appears in RNA as a hairpin followed by approximately eight uridines (U stretch) at the 3′ terminus…”
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Isolation and characterization of sigma(70)-retaining transcription elongation complexes from Escherichia coli by Bar-Nahum, G, Nudler, E

“…sigma(70) subunit is thought to be released from the core RNA polymerase (RNAP) upon the transition from initiation to elongation or shortly afterward. Here,…”
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The Riboswitch-Mediated Control of Sulfur Metabolism in Bacteria by Epshtein, Vitaly, Mironov, Alexander S., Nudler, Evgeny

“…Many operons in Gram-positive bacteria that are involved in methionine (Met) and cysteine (Cys) biosynthesis possess an evolutionarily conserved regulatory…”
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Transcription termination and anti‐termination in E. coli by Nudler, Evgeny, Gottesman, Max E.

“…Transcription termination in Escherichia coli is controlled by many factors. The sequence of the DNA template, the structure of the transcript, and the actions…”
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Catalysis of S-Nitrosothiols Formation by Serum Albumin: The Mechanism and Implication in Vascular Control by Rafikova, Olga, Rafikov, Ruslan, Nudler, Evgeny

“…Nitric oxide (NO·) is a short-lived physiological messenger. Its various biological activities can be preserved in a more stable form of S-nitrosothiols…”
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