Search Results - "Nsairat, Hamdi"

Liposomes: structure, composition, types, and clinical applications by Nsairat, Hamdi, Khater, Dima, Sayed, Usama, Odeh, Fadwa, Al Bawab, Abeer, Alshaer, Walhan

“…Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high…”
Get full text

Aptamers Chemistry: Chemical Modifications and Conjugation Strategies by Odeh, Fadwa, Nsairat, Hamdi, Alshaer, Walhan, Ismail, Mohammad A, Esawi, Ezaldeen, Qaqish, Baraa, Bawab, Abeer Al, Ismail, Said I

“…Soon after they were first described in 1990, aptamers were largely recognized as a new class of biological ligands that can rival antibodies in various…”
Get full text

Remote loading of curcumin-in-modified β-cyclodextrins into liposomes using a transmembrane pH gradient by Odeh, Fadwa, Nsairat, Hamdi, Alshaer, Walhan, Alsotari, Shrouq, Buqaien, Rula, Ismail, Said, Awidi, Abdalla, Al Bawab, Abeer

“…Curcumin (CRM) is a natural polyphenol with antioxidative, anti-inflammatory, and anticancer therapeutic properties. However, CRM therapeutic potential is…”
Get full text

Quality by Design Approach in Liposomal Formulations: Robust Product Development by Alshaer, Walhan, Nsairat, Hamdi, Lafi, Zainab, Hourani, Omar M, Al-Kadash, Abdulfattah, Esawi, Ezaldeen, Alkilany, Alaaldin M

“…Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal formulations are a major platform in nanomedicine, with more than…”
Get full text

Aptamer-functionalized pH-sensitive liposomes for a selective delivery of echinomycin into cancer cells by Lafi, Zainab, Alshaer, Walhan, Hatmal, Ma'mon M, Zihlif, Malek, Alqudah, Dana A, Nsairat, Hamdi, Azzam, Hanan, Aburjai, Talal, Bustanji, Yasser, Awidi, Abdalla

“…Echinomycin (quinomycin A) is a peptide antibiotic from the quinoxaline family, which has a DNA bifunctional intercalating activity and an inhibitor of…”
Get full text

Ran GTPase and Its Importance in Cellular Signaling and Malignant Phenotype by El-Tanani, Mohamed, Nsairat, Hamdi, Mishra, Vijay, Mishra, Yachana, Aljabali, Alaa A A, Serrano-Aroca, Ángel, Tambuwala, Murtaza M

“…Ran is a member of the Ras superfamily of proteins, which primarily regulates nucleocytoplasmic trafficking and mediates mitosis by regulating spindle…”
Get full text

Review on PLGA Polymer Based Nanoparticles with Antimicrobial Properties and Their Application in Various Medical Conditions or Infections by Shakya, Ashok K, Al-Sulaibi, Mazen, Naik, Rajashri R, Nsairat, Hamdi, Suboh, Sara, Abulaila, Abdelrahman

“…The rise in the resistance to antibiotics is due to their inappropriate use and the use of a broad spectrum of antibiotics. This has also contributed to the…”
Get full text

Grafting of anti-nucleolin aptamer into preformed and remotely loaded liposomes through aptamer-cholesterol post-insertion by Nsairat, Hamdi, Mahmoud, Ismail S, Odeh, Fadwa, Abuarqoub, Duaa, Al-Azzawi, Hafsa, Zaza, Rand, Qadri, Malak I, Ismail, Said, Al Bawab, Abeer, Awidi, Abdalla, Alshaer, Walhan

“…A new combination strategy of an active loading and active targeting approach was applied in this work. The liposomes actively loaded with Curcumin (CRM) (Lip…”
Get full text

Preparation, Characterization, and Anticancer Activity of PEGylated Nano Liposomal Loaded with Rutin against Human Carcinoma Cells (HT‐29) by Al‐Ekaid, Noorin Manhal, Al‐Samydai, Ali, Al‐deeb, Ibrahim, Nsairat, Hamdi, Khleifat, Khaled, Alshaer, Walhan

“…The discusses the development of rutin‐loaded nanoliposomes and their anti‐colorectal cancer activity against human carcinoma cells (HT‐29). The study…”
Get full text

Synthesis, Characterization, and Assessment of Anti-Cancer Potential of ZnO Nanoparticles in an In Vitro Model of Breast Cancer by Aljabali, Alaa A A, Obeid, Mohammad A, Bakshi, Hamid A, Alshaer, Walhan, Ennab, Raed M, Al-Trad, Bahaa, Al Khateeb, Wesam, Al-Batayneh, Khalid M, Al-Kadash, Abdulfattah, Alsotari, Shrouq, Nsairat, Hamdi, Tambuwala, Murtaza M

“…Advanced innovations for combating variants of aggressive breast cancer and overcoming drug resistance are desired. In cancer treatment, ZnO nanoparticles…”
Get full text

Encapsulation of echinomycin in cyclodextrin inclusion complexes into liposomes: in vitro anti-proliferative and anti-invasive activity in glioblastoma by Alshaer, Walhan, Zraikat, Manar, Amer, Amer, Nsairat, Hamdi, Lafi, Zainab, Alqudah, Dana A, Al Qadi, Enas, Alsheleh, Tasneem, Odeh, Fadwa, Alkaraki, Arwa, Zihlif, Malek, Bustanji, Yasser, Fattal, Elias, Awidi, Abdalla

“…Echinomycin, a DNA bis-intercalator peptide, belongs to the family of quinoxaline antibiotics. Echinomycin exhibits potent antitumor and antimicrobial…”
Get full text

Preparation, Optimization and In vitro Evaluation of Doxorubicin‐loaded into Hyaluronic Acid Coated Niosomes Against Breast Cancer by Faddah, Haya, Nsairat, Hamdi, Shalan, Naeem M., El‐Tanani, Mohamed, Alqudah, Dana A., Alshaer, Walhan

“…Doxorubicin (DOX) is widely used against solid tumors. Niosomes are self‐assembled nanocarriers of non‐ionic surfactants. DOX loaded into cationic niosomes…”
Get full text

Cinnamaldehyde-cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde in vitro anti-tumor activity by Al Tbakhi, Bayan, Nsairat, Hamdi, Alshaer, Walhan, Al-Kadash, Abdulfattah, Helal, Wissam, Alrawashdeh, Lubna, Day, Anthony, Assaf, Khaleel I, Hassouneh, Rola, Odeh, Fadwa, Al Bawab, Abeer

“…This study aimed to clarify the physico-chemical properties of cucurbit[7]uril (CB[7]) and cinnamaldehyde (Cinn) inclusion complexes (CB[7]-Cinn) and their…”
Get full text

Design, Preparation, and Characterization of Effective Dermal and Transdermal Lipid Nanoparticles: A Review by Khater, Dima, Nsairat, Hamdi, Odeh, Fadwa, Saleh, Mais, Jaber, Areej, Alshaer, Walhan, Al Bawab, Abeer, Mubarak, Mohammad S.

“…Limited permeability through the stratum corneum (SC) is a major obstacle for numerous skin care products. One promising approach is to use lipid nanoparticles…”
Get full text

Development of Pegylated Nano‐Phytosome Formulation with Oleuropein and Rutin to Compare Anti‐Colonic Cancer Activity with Olea Europaea Leaves Extract by Mahmood, Tabarek H., Al‐Samydai, Ali, Sulaibi, Mazen Al, Alqaraleh, Moath, Abed, Anas Ibrahim, Shalan, Naeem, Alsanabrah, Alaa, Alsotari, Shrouq Taiseer, Nsairat, Hamdi, Alshaer, Walhan

“…Olive leaf extract is a valuable source of phenolic compounds; primarily, oleuropein (major component) and rutin. This natural olive leaf extract has potential…”
Get full text

Synthesis of Mono-Amino Substituted γ-CD: Host-Guest Complexation and In Vitro Cytotoxicity Investigation by Odeh, Fadwa, Adaileh, Fedaa, Alshaer, Walhan, Nsairat, Hamdi, Alqudah, Dana A, Jaber, Areej M, Al Bawab, Abeer

“…Cyclodextrins (CDs) are cyclic oligosaccharides which can trap hydrophobic molecules and improve their chemical, physical, and biological properties. γ-CD…”
Get full text

Oleuropein impact on colorectal cancer by Nsairat, Hamdi, Jaber, Areej M, Faddah, Haya, Ahmad, Somaya

“…Colorectal cancer (CRC) is considered the third most common cancer in the world. In Mediterranean region, olives and olive oil play a substantial role in diet…”
Get full text

Lipid nanostructures for targeting brain cancer by Nsairat, Hamdi, Khater, Dima, Odeh, Fadwa, Al-Adaileh, Fedaa, Al-Taher, Suma, Jaber, Areej M., Alshaer, Walhan, Al Bawab, Abeer, Mubarak, Mohammad S.

“…Advancements in both material science and bionanotechnology are transforming the health care sector. To this end, nanoparticles are increasingly used to…”
Get full text

Biosensors for Fungal Detection by Nsairat, Hamdi, Jaber, Areej M, Al-Sulaibi, Mazen

“…Due to the serious threat of invasive fungal infections, there is an emergent need for improved a sensitive and more accurate diagnostic tests for detection of…”
Get full text

Recent advances in using liposomes for delivery of nucleic acid-based therapeutics by Nsairat, Hamdi, Alshaer, Walhan, Odeh, Fadwa, Esawi, Ezzaldeen, Khater, Dima, Bawab, Abeer Al, El-Tanani, Mohamed, Awidi, Abdalla, Mubarak, Mohammad S.

“…Nucleic acid therapeutics are rapidly expanding because of recent advancements in production and purification. This class of therapeutics may change the field…”
Get full text