Search Results - "Noya, Belkisyolé Alarcón de"
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Defects in immune response to Toxoplasma gondii are associated with enhanced HIV-1-related neurocognitive impairment in co-infected patients
Published in PloS one (24-05-2023)“…Human immunodeficiency virus-1 (HIV-1) and Toxoplasma gondii can invade the central nervous system and affect its functionality. Advanced HIV-1 infection has…”
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Ten years follow-up of the largest oral Chagas disease outbreak: Cardiological prospective cohort study
Published in PLoS neglected tropical diseases (01-10-2023)“…Background Chagas disease (ChD) is the most important endemy in Latin America. Some patients, develop chronic Chagasic cardiopathy (CCC) years after the acute…”
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Update on oral Chagas disease outbreaks in Venezuela: epidemiological, clinical and diagnostic approaches
Published in Memórias do Instituto Oswaldo Cruz (01-05-2015)“…Orally transmitted Chagas disease has become a matter of concern due to outbreaks reported in four Latin American countries. Although several mechanisms for…”
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Specific Recognition of β-Galactofuranose-Containing Glycans of Synthetic Neoglycoproteins by Sera of Chronic Chagas Disease Patients
Published in Molecules (Basel, Switzerland) (09-01-2022)“…Chagas disease (CD) can be accurately diagnosed by detecting in patients' blood using polymerase chain reaction (PCR). However, parasite-derived biomarkers are…”
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Trypanosoma cruzi: Time for International Recognition as a Foodborne Parasite
Published in PLoS neglected tropical diseases (02-06-2016)“…Outbreaks of foodborne Chagas disease are documented from 1966 [15] and oral transmission may always have been the usual infection route between wild and…”
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A Branched and Double Alpha-Gal-Bearing Synthetic Neoglycoprotein as a Biomarker for Chagas Disease
Published in Molecules (Basel, Switzerland) (01-09-2022)“…Chagas disease (CD) is caused by the parasite and affects 6-7 million people worldwide. The diagnosis is still challenging, due to extensive parasite diversity…”
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Development of Diagnostics for Chagas Disease: Where Should We Put Our Limited Resources?
Published in PLoS neglected tropical diseases (05-01-2017)“…According to the World Health Organization (WHO), one of the milestones set by the London Declaration for Chagas disease--the interruption of Chagas disease…”
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Characterization and Follow-Up of Trypanosoma cruzi Natural Populations Refractory to Etiological Chemotherapy in Oral Chagas Disease Patients
Published in Frontiers in cellular and infection microbiology (28-04-2021)“…We aimed to characterize the genetic constitution of natural populations involved in an Oral Chagas Disease (OCD) outbreak at a rural school of the community…”
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Nifurtimox response of Trypanosoma cruzi isolates from an outbreak of Chagas disease in Caracas, Venezuela
Published in Journal of vector borne diseases (01-07-2019)“…Background & objectives: In Venezuela, Chagas disease (ChD) is considered a serious health problem, with about 6 million people at risk; and acute outbreaks…”
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Low transmission areas of schistosomiasis in Venezuela: consequences on the diagnosis, treatment, and control
Published in Memórias do Instituto Oswaldo Cruz (01-10-2006)“…Schistosomiasis low transmission areas as Venezuela, can be defined as those where the vector exists, the prevalence of active cases is under 25%, individuals…”
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An ecological overview on the factors that drives to Trypanosoma cruzi oral transmission
Published in Acta tropica (01-11-2015)“…[Display omitted] •Deforestation reduce wildlife concentrating T. cruzi in few hosts.•Wildlife reduction promotes triatomines domiciliation looking for new…”
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Rapid Detection of Trypanosoma cruzi in Human Serum by Use of an Immunochromatographic Dipstick Test
Published in Journal of Clinical Microbiology (01-08-2010)“…We evaluated a commercially available immunochromatographic dipstick test to detect Trypanosoma cruzi infection in 366 human serum samples with known…”
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Clinical and ultrasound findings before and after praziquantel treatment among Venezuelan schistosomiasis patients
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-10-2007)“…Abdominal ultrasound can be a useful tool for diagnosing periportal fibrosis related to Schistosoma mansoni infection, and also for planning and monitoring the…”
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Ten-year follow-up of the largest oral Chagas disease outbreak. Laboratory biomarkers of infection as indicators of therapeutic failure
Published in Acta tropica (01-10-2021)“…•Laboratory biomarkers of infection as indicators of therapeutic failure.•Follow-up of the largest oral Chagas disease outbreak.•Response to treatment of…”
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Polymorphisms of the TLR4 gene: Risk factor for chronicity and severity in oral vectorial Chagas disease
Published in Experimental parasitology (01-07-2022)“…Chagas disease is one of the parasitic infections with the greatest socio-economic impact in Latin America. In Venezuela, epidemiological data has shown…”
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Toward the Establishment of a Single Standard Curve for Quantification of Trypanosoma cruzi Natural Populations Using a Synthetic Satellite Unit DNA Sequence
Published in The Journal of molecular diagnostics : JMD (01-05-2021)“…Accurate diagnostic tools and surrogate markers of parasitologic response to treatment are needed for managing Chagas disease. Quantitative real-time PCR…”
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Immunoinformatics and Pepscan strategies on the path of a peptide-based serological diagnosis of COVID19
Published in Journal of immunological methods (01-08-2021)“…Several diagnostic tools have been developed for clinical and epidemiological assays. RT-PCR and antigen detection tests are more useful for diagnosis of acute…”
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A standardized clinical database for research in Chagas disease: The NHEPACHA network
Published in PLoS neglected tropical diseases (15-08-2024)“…The NHEPACHA Iberoamerican Network, founded on the initiative of a group of researchers from Latin American countries and Spain, aims to establish a research…”
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Genetic Characterization of Trypanosoma cruzi I Populations from an Oral Chagas Disease Outbreak in Venezuela: Natural Resistance to Nitroheterocyclic Drugs
Published in ACS infectious diseases (10-03-2023)“…The oral transmission of Chagas disease (oCD) in Venezuela announced its appearance in 2007. Different from other populations affected by oCD and despite close…”
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Long-term comparative pharmacovigilance of orally transmitted Chagas disease: first report
Published in Expert review of anti-infective therapy (04-03-2017)“…Two old drugs are the only choice against Trypanosoma cruzi and little is known about their secondary effects in the acute stage of oral-transmitted Chagas…”
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