Search Results - "Nowsheen, S"

L3MBTL2 Orchestrates Ubiquitin Signaling After DNA Damage and Predicts Tumor Response to Radiation by Nowsheen, S

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The intersection between DNA damage response and cell death pathways by Nowsheen, S, Yang, E S

“…Apoptosis is a finely regulated process that serves to determine the fate of cells in response to various stresses. One such stress is DNA damage, which not…”
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Tissue invasion and metastasis: Molecular, biological and clinical perspectives by Jiang, W.G, Sanders, A.J, Katoh, M, Ungefroren, H, Gieseler, F, Prince, M, Thompson, S.K, Zollo, M, Spano, D, Dhawan, P, Sliva, D, Subbarayan, P.R, Sarkar, M, Honoki, K, Fujii, H, Georgakilas, A.G, Amedei, A, Niccolai, E, Amin, A, Ashraf, S.S, Ye, L, Helferich, W.G, Yang, X, Boosani, C.S, Guha, G, Ciriolo, M.R, Aquilano, K, Chen, S, Azmi, A.S, Keith, W.N, Bilsland, A, Bhakta, D, Halicka, D, Nowsheen, S, Pantano, F, Santini, D

“…Abstract Cancer is a key health issue across the world, causing substantial patient morbidity and mortality. Patient prognosis is tightly linked with…”
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Targeting DNA damage and repair: embracing the pharmacological era for successful cancer therapy by Aziz, K, Nowsheen, S, Pantelias, G, Iliakis, G, Gorgoulis, V G, Georgakilas, A G

“…DNA is under constant assault from genotoxic agents which creates different kinds of DNA damage. The precise replication of the genome and the continuous…”
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Treatment of acne with spironolactone: a retrospective review of 395 adult patients at Mayo Clinic, 2007–2017 by Roberts, E.E., Nowsheen, S., Davis, M.D.P., McEvoy, M.T., Newman, C.C., Sartori Valinotti, J.C., Sciallis, G.F., Torgerson, R.R., Wetter, D.A.

“…Background Few large studies have assessed spironolactone treatment of adult female acne. Objectives To explore the role of spironolactone in the treatment of…”
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The Polycomb Group Protein L3MBTL2 Modulates DNA Double Strand Break Repair and Predicts Response of Triple Negative Breast Cancer Cells to Poly (ADP-ribose) Polymerase Inhibition by Nowsheen, S, Mutter, R.W, Lou, Z

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The interplay between inflammation and oxidative stress in carcinogenesis by Nowsheen, S, Aziz, K, Kryston, T B, Ferguson, N F, Georgakilas, A

“…Emerging data suggest that primary dysfunction in the tumor microenvironment is crucial for carcinogenesis. These recent findings make a compelling case for…”
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Targeting HER Pathways to Render Breast Cancer Cells Susceptible to Poly (ADP-ribose) Polymerase (PARP) Inhibition by Yang, E.S, Nowsheen, S

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The Role of STAT-3 in Cetuximab-induced Radiosensitization in Head-and-Neck Cancer Cells by Bonner, J.A, Trummell, H, Nowsheen, S, Yang, E.S

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Patterns of Failure: Detailed Dosimetric Analysis of Glioblastoma Recurrence in the Era of Modern Chemoradiation Therapy by Hosotani, M, Laack, N.N, Pafundi, D.H, Nowsheen, S, Brinkmann, D.H

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Nanotechnology in cancer therapy: targeting the inhibition of key DNA repair pathways by Aziz, K, Nowsheen, S, Georgakilas, A G

“…Cancer therapy has been changing over the decades as we move away from the administration of broad spectrum cytotoxic drugs and towards the use of therapy…”
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Human HER2+ Breast Cancer Susceptibility to Poly(ADP-Ribose) Polymerase Inhibitors Independent of a Homologous Recombination Repair Defect by Yang, E.S, Nowsheen, S, Cooper, T, Bonner, J.A, LoBuglio, A.F

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Synthetic Lethal Interactions Between EGFR and PARP Inhibition in Triple Negative Breast Cancer by Nowsheen, S, Cooper, T, LoBuglio, A.F, Bonner, J.A, Yang, E.S

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Biomarkers to assess the targeting of DNA repair pathways to augment tumor response to therapy by Nowsheen, S, Whitley, A C, Yang, E S

“…Hyper-activation of DNA repair pathways can enable tumor cells to survive DNA damage. Therefore, targeting specific DNA repair pathways might prove efficacious…”
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BRCA1 Nuclear Export Sensitizes Prostate Cancer Cells to Poly (ADP-ribose) Polymerase (PARP) Inhibition via the CRM1/exportin Pathway by Klepczyk, L.C, Nowsheen, S, Xia, F, Yang, E.S

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Poly (ADP-Ribose) polymerase inhibition attenuates radiation-induced non-homologous end-joining repair and augments cervical cancer response to radiation by Yang, E, Nowsheen, S, Cooper, T, Landen, C, Bonner, J

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Towards personalized PARP therapy: XRT-induced Rad51 predicts re- sponse to ABT-888 in ovarian cancer by Shah, M, Nowsheen, S, Katre, A, Dobbin, Z, Erickson, B, Alvarez, R, Konstantinopoulos, P, Yang, E, Landen, C

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Targeting BRCA1 Localization to Augment Tumor Cell Susceptibility to Poly (ADP-ribose) Polymerase-1 (PARP1) Inhibition by Yang, S, Nowsheen, S, Xia, F

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MARCKS Regulates Growth, Radiation Sensitivity, and Is a Novel Prognostic Factor for Glioblastoma by Jarboe, J, Anderson, J.C, Duarte, C.W, Mehta, T, Nowsheen, S, Rohrbach, T.D, McCubrey, R.O, Gillespie, G.Y, Yang, E.S, Willey, C.D

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Inhibition of GSK3β Enhances Repair of Radiation-induced DNA Double Strand Breaks in Hippocampal Neurons by Nowsheen, S, Yang, E.S, Hallahan, D.E, Xia, F

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