Search Results - "Nowosielski, Marcin"

  • Showing 1 - 7 results of 7
Refine Results
  1. 1
    Detailed Mechanism of Squalene Epoxidase Inhibition by Terbinafine

    Detailed Mechanism of Squalene Epoxidase Inhibition by Terbinafine by Nowosielski, Marcin, Hoffmann, Marcin, Wyrwicz, Lucjan S, Stepniak, Piotr, Plewczynski, Dariusz M, Lazniewski, Michal, Ginalski, Krzysztof, Rychlewski, Leszek

    “…Squalene epoxidase (SE) is a key flavin adenine dinucleotide (FAD)-dependent enzyme of ergosterol and cholesterol biosynthetic pathways and an attractive…”
    Get full text
    Journal Article
    Save to List
    Saved in:
  2. 2
    Naphthalimides Selectively Inhibit the Activity of Bacterial, Replicative DNA Ligases and Display Bactericidal Effects against Tubercle Bacilli

    Naphthalimides Selectively Inhibit the Activity of Bacterial, Replicative DNA Ligases and Display Bactericidal Effects against Tubercle Bacilli by Korycka-Machala, Malgorzata, Nowosielski, Marcin, Kuron, Aneta, Rykowski, Sebastian, Olejniczak, Agnieszka, Hoffmann, Marcin, Dziadek, Jaroslaw

    Published in Molecules (Basel, Switzerland) (01-01-2017)
    “…The DNA ligases, enzymes that seal breaks in the backbones of DNA, are essential for all organisms, however bacterial ligases essential for DNA replication use…”
    Get full text
    Journal Article
    Save to List
    Saved in:
  3. 3
    Evaluation of DNA Primase DnaG as a Potential Target for Antibiotics

    Evaluation of DNA Primase DnaG as a Potential Target for Antibiotics by KURON, Aneta, KORYCKA-MACHALA, Malgorzata, BRZOSTEK, Anna, NOWOSIELSKI, Marcin, DOHERTY, Aidan, DZIADEK, Bozena, DZIADEK, Jaroslaw

    Published in Antimicrobial Agents and Chemotherapy (01-03-2014)
    “…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
    Get full text
    Journal Article
    Save to List
    Saved in:
  4. 4
    Exploring the Phase Space of Alpha-Synuclein with Replica Exchange Simulations

    Exploring the Phase Space of Alpha-Synuclein with Replica Exchange Simulations by Nowosielski, Marcin A., Bolhuis, Peter G.

    Published in Biophysical journal (27-01-2015)
    Get full text
    Journal Article
    Save to List
    Saved in:
  5. 5
    DFT study on hydroxy acid-lactone interconversion of statins: the case of atorvastatin

    DFT study on hydroxy acid-lactone interconversion of statins: the case of atorvastatin by Hoffmann, Marcin, Nowosielski, Marcin

    Published in Organic & biomolecular chemistry (07-10-2008)
    “…Atorvastatin (ATV), the best known HMG-CoA reductase inhibitor family member, undergoes pH-dependent hydroxy acid-lactone interconversion similar to other…”
    Get more information
    Journal Article
    Save to List
    Saved in:
  6. 6
    Do the substituent effects affect conformational freedom of squalene in hopene biosynthesis?

    Do the substituent effects affect conformational freedom of squalene in hopene biosynthesis? by Nowosielski, Marcin, Hoffmann, Marcin

    Published in Journal of molecular modeling (01-09-2011)
    “…The analysis of biochemical processes is one of the main challenges for modern computational chemistry. Probably the biggest issue facing scientists in this…”
    Get full text
    Journal Article
    Save to List
    Saved in:
  7. 7
    The MM2QM tool for combining docking, molecular dynamics, molecular mechanics, and quantum mechanics

    The MM2QM tool for combining docking, molecular dynamics, molecular mechanics, and quantum mechanics by Nowosielski, Marcin, Hoffmann, Marcin, Kuron, Aneta, Korycka-Machala, Malgorzata, Dziadek, Jaroslaw

    Published in Journal of computational chemistry (05-04-2013)
    “…The use of the MM2QM tool in a combined docking + molecular dynamics (MD) + molecular mechanics (MM) + quantum mechanical (QM) binding affinity prediction…”
    Get full text
    Journal Article
    Save to List
    Saved in:

Search Tools: