Search Results - "Nowikow, Christina"
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Chiral hydroxylation at the mononuclear nonheme Fe(II) center of 4-(S) hydroxymandelate synthase--a structure-activity relationship analysis
Published in PloS one (23-07-2013)“…(S)-Hydroxymandelate synthase (Hms) is a nonheme Fe(II) dependent dioxygenase that catalyzes the oxidation of 4-hydroxyphenylpyruvate to (S)-4-hydroxymandelate…”
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Journal Article -
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Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties
Published in Bioorganic & medicinal chemistry (01-10-2019)“…[Display omitted] Combretastatin A-4 (CA-4) is a highly cytotoxic natural product and several derivatives have been prepared which underwent clinical trial…”
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Journal Article -
3
Gram scale de novo synthesis of 2,4-diacetamido-2,4,6-trideoxy-d-galactose
Published in Carbohydrate research (15-02-2013)“…[Display omitted] ► An l-threonine derived aldehyde was used as chiral starting material. ► The carbon backbone of the target sugar was generated via a nitro…”
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4
Indium-Mediated Allenylation of Aldehydes and Its Application in Carbohydrate Chemistry: Efficient Synthesis of D-Ribulose and 1-Deoxy-D-ribulose
Published in European Journal of Organic Chemistry (01-03-2011)“…A two‐step reaction sequence starting with the indium‐mediated allenylation of aldehydes with 4‐bromo‐2‐butyn‐1‐ols and subsequent ozonolysis of the resulting…”
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Book Review Journal Article -
5
Chiral Hydroxylation at the Mononuclear Nonheme Fe Hydroxymandelate Synthase - A Structure-Activity Relationship Analysis
Published in PloS one (23-07-2013)“…(S)-Hydroxymandelate synthase (Hms) is a nonheme Fe(II) dependent dioxygenase that catalyzes the oxidation of 4-hydroxyphenylpyruvate to (S)-4-hydroxymandelate…”
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Journal Article -
6
Indium-Mediated Allenylation of Aldehydes and Its Application in Carbohydrate Chemistry: Efficient Synthesis of D-Ribulose and 1-Deoxy-D-ribulose (Eur. J. Org. Chem. 9/2011)
Published in European journal of organic chemistry (01-03-2011)“…The cover picture shows the application of an indium‐mediated allenylation reaction of aldehydes using 4‐bromo‐2‐butyn‐1‐ols to generate α‐hydroxyacetyl anion…”
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Journal Article