Search Results - "Nowecki, Zbigniew"

Ipatasertib plus paclitaxel for PIK3CA/AKT1/PTEN-altered hormone receptor-positive HER2-negative advanced breast cancer: primary results from cohort B of the IPATunity130 randomized phase 3 trial by Turner, Nicholas, Dent, Rebecca A., O’Shaughnessy, Joyce, Kim, Sung-Bae, Isakoff, Steven J., Barrios, Carlos, Saji, Shigehira, Bondarenko, Igor, Nowecki, Zbigniew, Lian, Qinshu, Reilly, Sarah-Jayne, Hinton, Heather, Wongchenko, Matthew J., Kovic, Bruno, Mani, Aruna, Oliveira, Mafalda

“…Purpose PI3K/AKT pathway alterations are frequent in hormone receptor-positive (HR+) breast cancers. IPATunity130 Cohort B investigated ipatasertib–paclitaxel…”
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The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study by Rutkowski, Piotr, Bylina, Elżbieta, Klimczak, Anna, Switaj, Tomasz, Falkowski, Sławomir, Kroc, Jacek, Lugowska, Iwona, Brzeskwiniewicz, Magdalena, Melerowicz, Wojciech, Osuch, Czesław, Mierzejewska, Ewa, Wasielewski, Kacper, Woźniak, Agnieszka, Grzesiakowska, Urszula, Nowecki, Zbigniew I, Siedlecki, Janusz A, Limon, Janusz

“…Gastrointestinal stromal tumors (GIST) mutational status is recognized factor related to the results of tyrosine kinase inhibitors therapy such as imatinib…”
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Prognosis in Patients With Sentinel Node–Positive Melanoma Is Accurately Defined by the Combined Rotterdam Tumor Load and Dewar Topography Criteria by VAN DER PLOEG, Augustinus P. T, VAN AKKOOI, Alexander C. J, VAN DEN HOUT, Mari F. C. M, VAN LEEUWEN, Paul A. M, VOIT, Christiane A, CATALDO, Francesco, TESTORI, Alessandro, ROBERT, Caroline, HOEKSTRA, Harald J, VERHOEF, Cornelis, SPATZ, Alain, EGGERMONT, Alexander M. M, RUTKOWSKI, Piotr, NOWECKI, Zbigniew I, MICHEJ, Wanda, MITRA, Angana, NEWTON-BISHOP, Julia A, COOK, Martin, VAN DER PLOEG, Iris M. C, NIEWEG, Omgo E

“…Prognosis in patients with sentinel node (SN)-positive melanoma correlates with several characteristics of the metastases in the SN such as size and site…”
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Retrospective Observational Study to Determine the Epidemiology and Treatment Patterns of Patients with Triple-Negative Breast Cancer by Rosińska, Magdalena, Dubiański, Roman, Konieczna, Aleksandra, Poleszczuk, Jan, Pawlik, Hubert, Nowecki, Zbigniew I, Kamiński, Eryk

“…Triple-negative breast cancer (TNBC) poses a serious therapeutic challenge due to the occurrence of frequently aggressive, heterogenic, and metastatic tumours…”
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The Survival Benefit to Patients with Positive Sentinel Node Melanoma After Completion Lymph Node Dissection May Be Limited to the Subgroup with a Primary Lesion Breslow Thickness Greater Than 1.0 and Less Than or Equal to 4 mm (pT2–pT3) by Nowecki, Zbigniew I., Rutkowski, Piotr, Michej, Wanda

“…Background The survival benefit of sentinel node biopsy is still controversial. The aim of our study was to assess the overall survival (OS; calculated both…”
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Effects of BRCA Germline Mutations on Triple-Negative Breast Cancer Prognosis by Nowecki, Zbigniew, Jagiełło-Gruszfeld, Agnieszka, Nowakowska, Dorota, Sarnowska, Elżbieta, Niwińska, Anna, Pogoda, Katarzyna, Siedlecki, Janusz

“…Germline BRCA1 and BRCA2 mutations confer an increased lifetime risk for breast cancer and ovarian cancer. Several studies have investigated prognosis among…”
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Sentinel node tumor burden according to the Rotterdam criteria is the most important prognostic factor for survival in melanoma patients: a multicenter study in 388 patients with positive sentinel nodes by van Akkooi, Alexander C J, Nowecki, Zbigniew I, Voit, Christiane, Schäfer-Hesterberg, Gregor, Michej, Wanda, de Wilt, Johannes H W, Rutkowski, Piotr, Verhoef, Cornelis, Eggermont, Alexander M M

“…The more intensive sentinel node (SN) pathologic workup, the higher the SN-positivity rate. This is characterized by an increased detection of cases with…”
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Clinical characterization, prognostic, and predictive values of HER2-low in patients with early breast cancer in the PALLAS trial (ABCSG-42/AFT-05/BIG-14-13/PrE0109) by Nader-Marta, Guilherme, Singer, Christian, Hlauschek, Dominik, DeMichele, Angela, Tarantino, Paolo, de Azambuja, Evandro, Pfeiler, Georg, Martin, Miguel, Balko, Justin M, Nowecki, Zbigniew, Balic, Marija, Brufsky, Adam M, Chan, Arlene, Morris, Patrick G, Haddad, Tufia, Loibl, Sibylle, Liu, Yuan, Soelkner, Lidija, Fesl, Christian, Mayer, Erica L, Gnant, Michael

“…Bidirectional crosstalk between HER2 and estrogen receptor (ER) pathways may influence outcomes and the efficacy of endocrine therapy (ET). Low HER2 expression…”
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Risk criteria and prognostic factors for predicting recurrences after resection of primary gastrointestinal stromal tumor by Rutkowski, Piotr, Nowecki, Zbigniew I, Michej, Wanda, Debiec-Rychter, Maria, Woźniak, Agnieszka, Limon, Janusz, Siedlecki, Janusz, Grzesiakowska, Urszula, Kakol, Michał, Osuch, Czesław, Polkowski, Marcin, Głuszek, Stanisław, Zurawski, Zbigniew, Ruka, Włodzimierz

“…The introduction of adjuvant imatinib in gastrointestinal stromal tumors (GISTs) raised debate over the accuracy of National Institutes of Health risk criteria…”
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Subcutaneous trastuzumab with pertuzumab and docetaxel in HER2-positive metastatic breast cancer: Final analysis of MetaPHER, a phase IIIb single-arm safety study by Kuemmel, Sherko, Tondini, Carlo A., Abraham, Jacinta, Nowecki, Zbigniew, Itrych, Bartosz, Hitre, Erika, Karaszewska, Bogusława, Juárez-Ramiro, Alejandro, Morales-Vásquez, Flavia, Pérez-García, Jose Manuel, Cardona-Huerta, Servando, Monturus, Estefania, Sequi, Marco, Restuccia, Eleonora, Benyunes, Mark, Martín, Miguel

“…Purpose Intravenous trastuzumab, pertuzumab, and docetaxel are first-line standard of care for patients with HER2-positive metastatic breast cancer (mBC)…”
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Neoadjuvant Pertuzumab Plus Trastuzumab in Combination with Docetaxel and Carboplatin in Patients with HER2-Positive Breast Cancer: Real-World Data from the National Institute of Oncology in Poland by Jagiełło-Gruszfeld, Agnieszka Irena, Rosinska, Magdalena, Meluch, Małgorzata, Pogoda, Katarzyna, Niwinska, Anna, Sienkiewicz, Renata, Grous, Aleksander, Winter, Paweł, Nowecki, Zbigniew I

“…Neoadjuvant systemic therapy has now become the standard in early breast cancer management. Chemotherapy in combination with trastuzumab +/- pertuzumab…”
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Coronary artery calcium score and other risk factors in patients at moderate and high risk of cancer therapy-related cardiovascular toxicity by Borowiec, Anna, Ozdowska, Patrycja, Rosinska, Magdalena, Zebrowska, Agnieszka Maria, Jagiello-Gruszfeld, Agnieszka, Jasek, Sławomir, Waniewska, Joanna, Kotowicz, Beata, Kosela-Paterczyk, Hanna, Lampka, Elzbieta, Pogoda, Katarzyna, Cieszanowski, Andrzej, Nowecki, Zbigniew, Walewski, Jan

“…The presence and burden of coronary artery calcium (CAC) is a strong predictor of cardiovascular events. Current guidelines of the European Society of…”
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Survival analysis and clinicopathological factors associated with false-negative sentinel lymph node biopsy findings in patients with cutaneous melanoma by Nowecki, Zbigniew I, Rutkowski, Piotr, Nasierowska-Guttmejer, Anna, Ruka, Wlodzimierz

“…We analyzed the outcomes and factors associated with false-negative (FN) results of sentinel lymph node (SLN) biopsy findings in patients with cutaneous…”
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The Megavoltage Radiation Therapy in Treatment of Patients With Advanced or Difficult Giant Cell Tumors of Bone by Ruka, Wlodzimierz, M.D., Ph.D, Rutkowski, Piotr, M.D., Ph.D, Morysiński, Tadeusz, M.D., Ph.D, Nowecki, Zbigniew, M.D., Ph.D, Zdzienicki, Marcin, M.D., Ph.D, Makula, Donata, M.D, Ptaszyński, Konrad, M.D., Ph.D, Bylina, Elżbieta, B.Sc, Grzesiakowska, Urszula, M.D., Ph.D

“…Purpose To assess the outcomes of radiotherapy, in terms of local control and treatment complications, of advanced or difficult giant cell tumors of bone…”
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Functional features of gene expression profiles differentiating gastrointestinal stromal tumours according to KIT mutations and expression by Ostrowski, Jerzy, Polkowski, Marcin, Paziewska, Agnieszka, Skrzypczak, Magdalena, Goryca, Krzysztof, Rubel, Tymon, Kokoszyñska, Katarzyna, Rutkowski, Piotr, Nowecki, Zbigniew I, Vel Dobosz, Anna Jerzak, Jarosz, Dorota, Ruka, Wlodzimierz, Wyrwicz, Lucjan S

“…Gastrointestinal stromal tumours (GISTs) represent a heterogeneous group of tumours of mesenchymal origin characterized by gain-of-function mutations in KIT or…”
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Melanoma without a Detectable Primary Site with Metastases to Lymph Nodes by RUTKOWSKI, PIOTR, NOWECKI, ZBIGNIEW I., DZIEWIRSKI, WIRGINIUSZ, ZDZIENICKI, MARCIN, PIEÑKOWSKI, ANDRZEJ, SALAMACHA, MACIEJ, MICHEJ, WANDA, TREPKA, SLAWOMIR, BYLINA, ELZBIETA, RUKA, WLODZIMIERZ

“…OBJECTIVE To compare outcomes of patients with clinical nodal melanoma metastases that occurred without a detectable primary tumor (melanoma of unknown primary…”
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The long-term results and prognostic significance of cutaneous melanoma surgery using sentinel node biopsy with triple technique by Rutkowski, Piotr, Szydłowski, Konrad, Nowecki, Zbigniew I, Sałamacha, Maciej, Goryń, Tomasz, Mitręga-Korab, Beata, Pieńkowski, Andrzej, Dziewirski, Wirginiusz, Zdzienicki, Marcin

“…The sentinel lymph node biopsy (SLN) is a basic staging method in all primary cutaneous melanomas ≥pT1b. The standard technique is a triple technique…”
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Adjuvant vaccination with melanoma antigen-pulsed dendritic cells in stage III melanoma patients by Markowicz, Sergiusz, Nowecki, Zbigniew I., Rutkowski, Piotr, Lipkowski, Andrzej W., Biernacka, Marzena, Jakubowska-Mucka, Anna, Switaj, Tomasz, Misicka, Aleksandra, Skurzak, Henryk, Polowniak-Pracka, Hanna, Walewski, Jan

“…Dendritic cells may be successfully used to induce in vivo-specific anti-tumor responses when combined with the appropriate antigen in the appropriate context…”
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Cutaneous melanoma with nodal metastases in elderly people by Rutkowski, Piotr, Nowecki, Zbigniew I., Zdzienicki, Marcin, Michej, Wanda, Symonides, Malgorzata, Rosinska, Magdalena, Dziewirski, Wirginiusz, Bylina, Elzbieta, Ruka, Wlodzimierz

“…Background  The impact of age on melanoma patient outcomes is uncertain. Objective  The aim of the study was to analyze the characteristics and treatment…”
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Surgery combined with intraoperative brachytherapy in the treatment of retroperitoneal sarcomas by Dziewirski, Wirginiusz, Rutkowski, Piotr, Nowecki, Zbigniew I, Sałamacha, Maciej, Morysiński, Tadeusz, Kulik, Anna, Kawczyńska, Maria, Kasprowicz, Anetta, Lyczek, Jarosław, Ruka, Włodzimierz

“…The purpose of this study was to analyze the results of treatment of retroperitoneal soft tissue sarcomas (RSTS) by surgery combined with intraoperative…”
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