Search Results - "Nowe, Ulrike"

The pyrrole moiety as a template for COX-1/COX-2 inhibitors by Dannhardt, Gerd, Kiefer, Werner, Krämer, Godehard, Maehrlein, Sabine, Nowe, Ulrike, Fiebich, Bernd

“…Aroyl- and thiophene-substituted pyrrole derivatives have been synthesized as a new class of COX-1/COX-2 inhibitors. The inhibition of COX-1 was evaluated in a…”
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Convergent synthesis and preliminary biological evaluations of the stilbenolignan (+/-)-aiphanol and various congeners by Banwell, Martin G, Bezos, Anna, Chand, Satish, Dannhardt, Gerd, Kiefer, Werner, Nowe, Ulrike, Parish, Christopher R, Savage, G Paul, Ulbrich, Holger

“…Treatment of an equimolar mixture of stilbene 7 and cinnamyl alcohol 8 with silver carbonate in acetone-benzene afforded a ca. 2:1:2:1 mixture of the…”
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Effect of Flavonol Derivatives on the Carrageenin-Induced Paw Edema in the Rat and Inhibition of Cyclooxygenase-1 and 5-Lipoxygenase in Vitro by Sobottka, Andrea M., Werner, Wolfgang, Blaschke, Gottfried, Kiefer, Werner, Nowe, Ulrike, Dannhardt, Gerd, Schapoval, Elfrides E. S., Schenkel, Eloir P., Scriba, Gerhard K.E.

“…Alkoxyflavonols were synthesized by the Algar‐Flynn‐Oyamada (AFO) cyclization of chalcones. Hydroxyflavonols were prepared by dealkylation of methoxyflavonols…”
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Effect of Flavonol Derivatives on the Carrageenin-Induced Paw Edema in the Rat and Inhibition of Cyclooxygenase-1 and 5-Lipoxygenasein Vitro by Sobottka, Andrea M., Werner, Wolfgang, Blaschke, Gottfried, Kiefer, Werner, Nowe, Ulrike, Dannhardt, Gerd, Schapoval, Elfrides E. S., Schenkel, Eloir P., Scriba, Gerhard K.E.

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Non-steroidal anti-inflammatory agents, Part 24. Pyrrolidino enaminones as models to mimic arachidonic acid by Dannhardt, G, Bauer, A, Nowe, U

“…The pyrrolidino enaminones, with the carboxylic acid chain fixed at the nitrogen, inhibit cyclooxygenase more potently or selectively than 5-lipoxygenase…”
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Non-steroidal anti-inflammatory agents, Part 19. E-2-pyrrolizin-5-yl acrylic acids as potent dual or selective inhibitors of bovine cyclooxygenase and 5-lipoxygenase by Dannhardt, G, Kiefer, W, Nowe, U

“…The pyrrolizinyl substituted acrylic acid derivatives represent another class of dual and selective inhibitors of cyclooxygenase and 5-lipoxygenase. By…”
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Non-steroidal anti-inflammatory agents, Part 20. Method for testing non-steroidal anti-inflammatories: the modified hen's egg chorioallantoic membrane test (HET-CAM test) compared to other procedures by Dannhardt, G, Kreher, M, Nowe, U, Pies, A

“…The delay of onset of irritation phenomena at the chorioallantoic membrane of incubated hen's eggs, a parameter for anti-inflammatory activity, was determined…”
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