Search Results - "Nowak Göttl, Ulrike"
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International pediatric thrombosis network to advance pediatric thrombosis research: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis
Published in Journal of thrombosis and haemostasis (01-04-2021)“…Pediatric thromboembolism is a rare and heterogenous disease. As a result, there is a paucity of knowledge with regard to natural history, management, and…”
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Impact of high‐risk thrombophilia status on recurrence among children with a first non‐central‐venous‐catheter‐associated VTE: an observational multicentre cohort study
Published in British journal of haematology (01-10-2016)“…Summary Deficiency of antithrombin (AT), protein C (PC) or protein S (PS) constitutes a major risk factor for venous thromboembolism (VTE). Individuals at high…”
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ADAMTS12, a new candidate gene for pediatric stroke
Published in PloS one (20-08-2020)“…We recently reported a family-based genome wide association study (GWAS) for pediatric stroke pointing our attention to two significantly associated genes of…”
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Impact of Inherited Thrombophilia on Venous Thromboembolism in Children : A Systematic Review and Meta-Analysis of Observational Studies
Published in Circulation (New York, N.Y.) (23-09-2008)“…The aim of the present study was to estimate the impact of inherited thrombophilia (IT) on the risk of venous thromboembolism (VTE) onset and recurrence in…”
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Health-related quality of life in children and adolescents with stroke, self-reports, and parent/proxies reports: Cross-sectional investigation
Published in Annals of neurology (01-07-2011)“…Objective: Limited data are available on health‐related quality of life (HR‐QoL) in pediatric stroke survivors. The aim of the present study was to assess…”
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Eptacog beta efficacy and safety in the treatment and control of bleeding in paediatric subjects (<12 years) with haemophilia A or B with inhibitors
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-07-2022)“…Introduction Eptacog beta is a new recombinant activated human factor VII bypassing agent approved in the United States for the treatment and control of…”
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Role of reduced ADAMTS13 in arterial ischemic stroke: A Pediatric Cohort Study
Published in Annals of neurology (01-01-2013)“…Objective: Previous studies in adults and mice have implicated ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13),…”
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Role of endogenous testosterone concentration in pediatric stroke
Published in Annals of neurology (01-12-2009)“…Previous studies have indicated a male predominance in pediatric stroke. To elucidate this gender disparity, total testosterone concentration was measured in…”
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Rare Variants in the ADAMTS13 Von Willebrand Factor–Binding Domain Contribute to Pediatric Stroke
Published in Circulation. Cardiovascular genetics (01-08-2016)“…BACKGROUND—Recently, we reported a gene network of ADAMTS (A Disintegrin-like and Metalloprotease with Thrombospondin motifs) genes as central component of the…”
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Subcutaneous protein C concentrate in the management of severe protein C deficiency – experience from 12 centres
Published in British journal of haematology (01-02-2014)“…Summary Since the first description of subcutaneous protein C concentrate as treatment for severe protein C deficiency in 1996, further cases have been…”
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Recurrent thromboembolism in infants and children suffering from symptomatic neonatal arterial stroke: a prospective follow-up study
Published in Stroke (1970) (01-12-2003)“…The present study was performed to evaluate the rate of recurrent symptomatic thromboembolism with respect to prothrombotic risk factors and underlying…”
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Cerebral venous thrombosis in children: A multifactorial origin
Published in Circulation (New York, N.Y.) (16-09-2003)“…The present study was performed to assess the association of prothrombotic risk factors and underlying conditions (infections, vascular trauma, immobilization,…”
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Intracranial bleeding under vitamin K antagonists or direct oral anticoagulants: results of the RADOA registry
Published in Neurological research and practice (02-05-2022)“…The use of direct oral anticoagulants (DOAC) has increased sharply and DOAC are the oral anticoagulant therapy (OAT) of choice for the majority of patients…”
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Familial Elevated Factor VIII in Children With Symptomatic Venous Thrombosis and Post-Thrombotic Syndrome: Results of a Multicenter Study
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2006)“…OBJECTIVE—To evaluate the role of factor (F) VIII in children with non-cancer related venous thrombosis (DVT), post-thrombotic syndrome (PTS) or recurrent DVT…”
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Anticoagulation in Childhood-Onset Arterial Ischemic Stroke With Nonmoyamoya Arteriopathy Findings From the Colorado and German (COAG) Collaboration
Published in Stroke (1970) (01-08-2009)“…Background and Purpose— Childhood arterial ischemic stroke treatment guidelines recommend extended anticoagulation in cardioembolism and dissection. We sought…”
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Proteomic and other mass spectrometry based "omics" biomarker discovery and validation in pediatric venous thromboembolism and arterial ischemic stroke: Current state, unmet needs, and future directions
Published in Proteomics. Clinical applications (01-12-2014)“…Venous thromboembolism (VTE) and arterial ischemic stroke (AIS) are increasingly‐recognized health conditions in children, with both acute and chronic…”
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Symptomatic ischemic stroke in full-term neonates : Role of acquired and genetic prothrombotic risk factors
Published in Stroke (1970) (01-10-2000)“…The present multicenter case-control study was prospectively designed to assess the extent to which single and combined clotting factor abnormalities influence…”
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Spectrum of molecular defects and mutation detection rate in patients with mild and moderate hemophilia A
Published in Human mutation (01-01-2007)“…The amount of residual F8 (FVIII:C) determines the clinical severity of hemophilia A. Recently, we showed that the mutation detection rate in severely affected…”
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Increased lipoprotein(a) is an important risk factor for venous thromboembolism in childhood
Published in Circulation (New York, N.Y.) (17-08-1999)“…Serum levels of lipoprotein(a) [Lp(a)] are determined largely by genetic variation in the gene encoding for apolipoprotein(a) [apo(a)], the specific protein…”
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Increased lipoprotein (a) levels as an independent risk factor for venous thromboembolism
Published in Blood (15-11-2000)“…Elevation of serum lipoprotein (a) (Lp[a]) is a known risk factor predisposing to cardiovascular and cerebrovascular disease. However, little is known about…”
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