Search Results - "Nowak, Steven"

Impact of Physicochemical Properties of Cellulosic Polymers on Supersaturation Maintenance in Aqueous Drug Solutions by Hong, Shiqi, Nowak, Steven A., Wah, Chan Lai

“…The precipitation inhibitory effect of cellulosic polymers in relation to their physicochemical properties was studied. Using a poorly water-soluble model…”
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Fast and sensitive method for the determination of trace 1,2,4-triazole and 4-amino-1,2,4-triazole by hydrophilic interaction liquid chromatography (HILIC) in antifungal drug substance by Chen, Quan, Zielinski, Dorota, Nowak, Steven A.

“…An HILIC method was developed to quantitatively determine trace amounts of 1,2,4-triazole and 4-amino-1,2,4-triazole in fluconazole drug substance. Separation…”
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High drug load, stable, manufacturable and bioavailable fenofibrate formulations in mesoporous silica: a comparison of spray drying versus solvent impregnation methods by Hong, Shiqi, Shen, Shoucang, Tan, David Cheng Thiam, Ng, Wai Kiong, Liu, Xueming, Chia, Leonard S O, Irwan, Anastasia W, Tan, Reginald, Nowak, Steven A, Marsh, Kennan, Gokhale, Rajeev

“…Encapsulation of drugs in mesoporous silica using co-spray drying process has been recently explored as potential industrial method. However, the impact of…”
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DEVELOPMENT OF DIRECT SERIAL COUPLING OF HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY AND REVERSED-PHASE COLUMNS FOR THE SIMULTANEOUS ANALYSIS OF ANTI-TUBERCULOSIS DRUGS by Tham, Lai Yee, Tan, Lik Tong, Nowak, Steven A.

“…The use of HPLC-MS and -UV systems are preferred methods for the detection of pharmaceutical drugs. In this study, direct serial coupling of HILIC to a…”
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Science- and Risk-Based Stability Strategies to Support Product Lifecycle Changes by McCaig, Lori, Nowak, Steven, Abbott, Alexander, Carhart, Jenny, McMahon, Megan E., Debie, Elke, Li, Hanlin, Maina, Francis, Ji, Andrea J., Fu, Mingkun, Wu, Yan, Lennard, Andrew, Mazzeo, Tony, Wolfe, Chad, Timpano, Robert, Babayan, Yelizaveta, Gruenig, Lars

“…ICH Q12 asserts that science- and risk-based approaches are applicable to stability studies supporting Chemistry, Manufacturing and Controls (CMC)…”
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Factor VII activating protease (FSAP) influences vascular remodeling in the mouse hind limb ischemia model by Herold, Joerg, Nowak, Steven, Kostin, Sawa, Daniel, Jan-Marcus, Francke, Alexander, Subramaniam, Saravanan, Braun-Dullaeus, Ruediger C, Kanse, Sandip M

“…Investigations in factor VII activating protease (FSAP) mice suggest a role for FSAP in stroke, thrombosis and neointima formation. Here, we analyzed the role…”
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High-data throughput using laser-based, time-resolved fluorometry by Nowak, Steven Alan

“…High-data throughput can achieve two goals in time-resolved fluorescence. It can produce very high signal-to-noise ratio data in collection times normally…”
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GMPs for Method Validation in Early Development by Chambers, Donald, Guo, Gary, Kleintop, Brent, Rasmussen, Henrik, Deegan, Steve, Nowak, Steven, Patterson, Kristin, Spicuzza, John, Szulc, Michael, Tombaugh, Karla, Trone, Mark D, Yuabova, Zhanna

“…The authors, part of the International Consortium on Innovation and Quality in Pharmaceutical Development (IQ Consortium), explore and define common industry…”
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GMPs for method validation in early development: an industry perspective (Part II) by Chambers, Donald, Guo, Gary, Kleintop, Brent, Rasmussen, Henrik, Deegan, Steve, Nowak, Steven, Patterson, Kristin, Spicuzza, John, Szulc, Michael, Tombaugh, Karla, Trone, Mark D, Yuabova, Zhanna

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