Search Results - "Nowak, R A"

EMMPRIN is secreted by human uterine epithelial cells in microvesicles and stimulates metalloproteinase production by human uterine fibroblast cells by Braundmeier, A G, Dayger, C A, Mehrotra, P, Belton, Jr, R J, Nowak, R A

“…Endometrial remodeling is a physiological process involved in the gynecological disease, endometriosis. Tissue remodeling is directed by uterine fibroblast…”
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Extracellular Matrix Metalloproteinase Inducer Regulates Metalloproteinases in Human Uterine Endometrium by Braundmeier, A. G., Fazleabas, A. T., Lessey, B. A., Guo, H., Toole, B. P., Nowak, R. A.

“…Context: Endometrial remodeling occurs during each menstrual cycle in women and also during the establishment of endometriosis. Both processes involve the…”
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Changes in small intestinal nutrient transport and barrier function after lipopolysaccharide exposure in two pig breeds by Albin, D.M, Wubben, J.E, Rowlett, J.M, Tappenden, K.A, Nowak, R.A

“…Specific pig breeds with unique characteristics have been developed, and the current study sought to characterize some of these differences. Using modified…”
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Extracellular matrix metalloproteinase inducer expression in the baboon endometrium: menstrual cycle and endometriosis by Braundmeier, A G, Fazleabas, A T, Nowak, R A

“…Extracellular matrix metalloproteinase inducer (EMMPRIN; BSG) regulates tissue remodeling through matrix metalloproteinases (MMPs). In human and non-human…”
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Isolation and characterization of heparin-binding growth factors in human leiomyomas and normal myometrium by MANGRULKAR, R. S, ONO, M, ISHIKAWA, M, TAKASHIMA, S, KLAGSBRUN, M, NOWAK, R. A

“…Uterine leiomyomas (fibroids) are benign, smooth muscle cell (SMC) tumors of the myometrium containing abundant extracellular matrix (ECM). Heparin-binding…”
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Pirfenidone : A novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production by LEE, B.-S, MARGOLIN, S. B, NOWAK, R. A

“…There are currently no effective, long-term drug therapies for the treatment of leiomyomas. Pirfenidone (Marnac, Inc.) is an antifibrotic agent that is being…”
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Expression of the fibroblast growth factor receptor in women with leiomyomas and abnormal uterine bleeding by ANANIA, C. A, STEWART, E. A, QUADE, B. J, HILL, J. A, NOWAK, R. A

“…Basic fibroblast growth factor (bFGF) is a regulator of angiogenesis which is overexpressed in leiomyomas compared with matched myometrium. To understand the…”
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Human leiomyoma smooth muscle cells show increased expression of transforming growth factor-beta 3 (TGF beta 3) and altered responses to the antiproliferative effects of TGF beta by Lee, B S, Nowak, R A

“…Transforming growth factor-betas (TGF betas) are multifunctional peptides that regulate growth and differentiation in a variety of cells. The goals of this…”
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Messenger ribonucleic acid for the gonadal luteinizing hormone/human chorionic gonadotropin receptor is not present in human endometrium by Stewart, E A, Sahakian, M, Rhoades, A, Van Voorhis, B J, Nowak, R A

“…To determine whether messenger RNA for the gonadal LH/hCG receptor is present in human endometrium with the use of reverse-transcriptase polymerase chain…”
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Production of prolactin by smooth muscle cells cultured from human uterine fibroid tumors by Nowak, R A, Rein, M S, Heffner, L J, Friedman, A J, Tashjian, Jr, A H

“…Uterine leiomyomas, which are myometrial smooth muscle tumors, secrete PRL. We investigated the actions of several hormones known to stimulate PRL secretion by…”
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Transforming growth factor-β stimulates mouse blastocyst outgrowth through a mechanism involving parathyroid hormone-related protein by NOWAK, R. A, HAIMOVICI, F, BIGGERS, J. D, ERBACH, G. T

“…The goals of this study were 1) to compare the effects of transforming growth factor-beta (TGF-beta) and parathyroid hormone-related protein (PTHrP) on mouse…”
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The myometrium of postmenopausal women produces prolactin in response to human chorionic gonadotropin and alpha-subunit in vitro by Stewart, E A, Jain, P, Penglase, M D, Friedman, A J, Nowak, R A

“…To examine the effect of equimolar concentrations of hCG and dissociated alpha-subunit on PRL production by leiomyoma and myometrial tissue obtained from…”
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Prolactin is an autocrine or paracrine growth factor for human myometrial and leiomyoma cells by Nowak, R A, Mora, S, Diehl, T, Rhoades, A R, Stewart, E A

“…To test the hypothesis that prolactin (PRL) acts as a mitogenic growth factor for human leiomyoma and myometrial cells. To test this hypothesis, we performed…”
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RU486 suppresses prolactin production in explant cultures of leiomyoma and myometrium by Stewart, E A, Austin, D J, Jain, P, Penglase, M D, Nowak, R A

“…To assess the action of RU486 (mifepristone), in the presence and absence of P, on PRL production by explant cultures of leiomyoma and myometrium. Explant…”
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Interferon-α is a Potent Inhibitor of Basic Fibroblast Growth Factor-Stimulated Cell Proliferation in Human Uterine Cells by LEE, BYUNG-SEOK, STEWART, ELIZABETH A., SAHAKIAN, MARINE, NOWAK, ROMANA A.

“…PROBLEM: Abnormal uterine bleeding is a significant health problem for many women and is the number‐one reason for performing hysterectomy in the United…”
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Increased expression of messenger RNA for collagen type I, collagen type III, and fibronectin in myometrium of pregnancy by Stewart, Elizabeth A., Floor, Amy E., Jain, Prachee, Nowak, Romana A.

“…To determine the expression of the extracellular matrix proteins collagen type I, collagen type III, and fibronectin by immunohistochemistry, and the messenger…”
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Leiomyoma-related bleeding: a classic hypothesis updated for the molecular era by Stewart, EA, Nowak, RA

“…Leiomyomas are an important cause of menorrhagia and other forms of abnormal uterine bleeding. The pathogenesis of this process is largely unknown, however. A…”
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Changes in small intestinal nutrient transport and barrier function after lipopolysaccharide exposure in two pig breeds1 by Albin, D. M., Wubben, J. E., Rowlett, J. M., Tappenden, K. A., Nowak, R. A.

“…Specific pig breeds with unique characteristics have been developed, and the current study sought to characterize some of these differences. Using modified…”
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Relative overexpression of the parathyroid hormone-related protein gene in human leiomyomas by Weir, E C, Goad, D L, Daifotis, A G, Burtis, W J, Dreyer, B E, Nowak, R A

“…Uterine leiomyomas or fibroids are common among women of reproductive age, but their biology is poorly understood. The PTH-related protein (PTHrP) has been…”
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HMGIC expression in human adult and fetal tissues and in uterine leiomyomata by Gattas, Gilka J.F., Quade, Bradley J., Nowak, Romana A., Morton, Cynthia C.

“…The high‐mobility‐group (HMG) protein gene, HMGIC, is localized to chromosome 12, band q15, a region often rearranged in benign mesenchymal tumors, including…”
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