Search Results - "Nowak, Paweł Mateusz"
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The Acid-Base/Deprotonation Equilibrium Can Be Studied with a MicroScale Thermophoresis (MST)
Published in Molecules (Basel, Switzerland) (21-01-2022)“…MicroScale thermophoresis (MST) is a rapidly developing bioanalytical technique used routinely for the examination of ligand-target affinity. It has never been…”
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2
Determination of acid dissociation constant of 20 coumarin derivatives by capillary electrophoresis using the amine capillary and two different methodologies
Published in Journal of Chromatography A (13-05-2016)“…•PKa of 20 coumarin derivatives has been determined by capillary electrophoresis.•Coumarins’ acidity strongly depends on chemical structure (pKa between…”
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3
Comprehensive Assessment of Flow and Other Analytical Methods Dedicated to the Determination of Zinc in Water
Published in Molecules (Basel, Switzerland) (26-06-2021)“…An original strategy to evaluate analytical procedures is proposed and applied to verify if the flow-based methods, generally favorable in terms of green…”
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ChlorTox Base – a useful source of information on popular reagents in terms of chemical hazards and greenness assessment
Published in Green Analytical Chemistry (01-09-2023)“…•674 chemical substances characterized in terms of hazards.•WHN values as the main parameter determining how hazardous in overall is given reagent.•Easy use of…”
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5
The First Online Capillary Electrophoresis-Microscale Thermophoresis (CE-MST) Method for the Analysis of Dynamic Equilibria—The Determination of the Acidity Constant of Fluorescein Isothiocyanate
Published in Molecules (Basel, Switzerland) (06-08-2022)“…This article presents the first successful application of a capillary electrophoresis-microscale thermophoresis tandem technique (CE-MST) for determining the…”
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6
Carbon footprint of the analytical laboratory and the three-dimensional approach to its reduction
Published in Green Analytical Chemistry (01-03-2023)“…•Electricity consumption studied for several laboratory instruments (separation techniques).•Carbon dioxide emission estimated based on the empirical data,…”
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7
White Analytical Chemistry: An approach to reconcile the principles of Green Analytical Chemistry and functionality
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-05-2021)“…The concept of White Analytical Chemistry (WAC) is presented as an extension of Green Analytical Chemistry (GAC). We propose the 12 WAC principles as an…”
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Simultaneous quantification of food colorants and preservatives in sports drinks by the high performance liquid chromatography and capillary electrophoresis methods evaluated using the red-green-blue model
Published in Journal of Chromatography A (07-06-2020)“…•Food preservatives and colorants quantified in sports drinks by CE and HPLC methods.•Amounts of colorants are rather safe, whereas preservatives, potential…”
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9
simple method for assessment and minimization of errors in determination of electrophoretic or electroosmotic mobilities and velocities associated with the axial electric field distortion
Published in Electrophoresis (01-12-2015)“…It is commonly accepted that the modern CE instruments equipped with efficient cooling system enable accurate determination of electrophoretic or…”
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10
A Perspective of the Comprehensive and Objective Assessment of Analytical Methods Including the Greenness and Functionality Criteria: Application to the Determination of Zinc in Aqueous Samples
Published in Frontiers in chemistry (14-10-2021)“…The recently proposed concept of White Analytical Chemistry (WAC), referring to the Red-Green-Blue color model, combines ecological aspects (green) with…”
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Overview of the three multicriteria approaches applied to a global assessment of analytical methods
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-12-2020)“…Critical and global evaluation of analytical methods should be one of the primary goals in analytical chemistry. A holistic approach, however, requires a look…”
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12
Comparison of various sample preparation methods for benzodiazepines in terms of the principles of white analytical chemistry
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-02-2024)“…Benzodiazepines are highly prevalent class of drugs utilized worldwide. They have been used as antidepressants and tranquilizers while also possessing the…”
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13
Exploring a new format of thermophoretic measurement – Stop-flow microscale thermophoresis in the narrow-bore transparent capillary
Published in Microchemical journal (01-09-2024)“…[Display omitted] •a new format of thermophoretic measurement presented.•narrow-bore transparent capillary: miniaturization, multiple measurements, coupling…”
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14
Origin of Remarkably Different Acidity of HydroxycoumarinsJoint Experimental and Theoretical Studies
Published in The journal of physical chemistry. B (04-05-2017)“…In the present work the origin of highly varied acidity of hydroxycoumarins (pK a values) has been for the first time investigated by joint experimental and…”
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15
Differentiation of isomeric metabolites of carbamazepine based on acid-base properties; Experimental vs theoretical approach
Published in Journal of Chromatography A (16-08-2021)“…•The acidity (pKa) of carbamazepine isomeric derivatives was studied.•Thermodynamics and structural effects contributing to deprotonation were…”
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A sustainable approach for the stability study of psychotropic substances using vitreous humor and liver as alternative matrices
Published in Analytical and bioanalytical chemistry (01-09-2022)“…The stability of psychotropic substances representing various drug groups important from the perspective of forensic chemistry, including benzodiazepines,…”
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17
Influence of pH measurement inaccuracy on the values of acidity constant determined on the basis of electrophoretic and thermophoretic data
Published in Microchemical journal (01-10-2022)“…[Display omitted] •The impact of pH error on pKa values was analyzed.•The electrophoretic and thermophoretic methods were considered.•Resulting uncertainty of…”
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18
Improving repeatability of capillary electrophoresis—a critical comparison of ten different capillary inner surfaces and three criteria of peak identification
Published in Analytical and bioanalytical chemistry (01-07-2017)“…A poor repeatability of migration times caused by the fluctuations of electroosmotic flow (EOF) is an inherent weakness of capillary electrophoresis. Most…”
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19
Thermodynamics of acid-base dissociation of several cathinones and 1‐phenylethylamine, studied by an accurate capillary electrophoresis method free from the Joule heating impact
Published in Journal of Chromatography A (02-03-2018)“…•An easy method for reducing the impact of Joule heating on pKa values was shown.•The magnitude of related errors in pKa, ΔH° and -TΔS° values was…”
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Assessment and Comparison of the Overall Analytical Potential of Capillary Electrophoresis and High-Performance Liquid Chromatography Using the RGB Model: How Much Can We Find Out?
Published in Chromatographia (01-09-2020)“…The choice between capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) is not easy and depends on many factors. An attempt to…”
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