Search Results - "Nowak, NJ"

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes by Hatten, Mary E, Heintz, Nathaniel, Gong, Shiaoching, Zheng, Chen, Doughty, Martin L, Losos, Kasia, Didkovsky, Nicholas, Schambra, Uta B, Nowak, Norma J, Joyner, Alexandra, Leblanc, Gabrielle

“…The mammalian central nervous system (CNS) contains a remarkable array of neural cells, each with a complex pattern of connections that together generate…”
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Molecular Study of Malignant Gliomas Treated with Epidermal Growth Factor Receptor Inhibitors: Tissue Analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01 by LASSMAN, Andrew B, ROSSI, Michael R, WILSON, Richard, NOWAK, Norma J, COWELL, John K, DEANGELIS, Lisa M, WEN, Patrick, GILBERT, Mark R, CHANG, Susan, YUNG, W. A, PRADOS, Michael, HOLLAND, Eric C, RAZIER, Jeffrey R, ABREY, Lauren E, LIEBERMAN, Frank S, GREFE, Chelsea N, LAMBORN, Kathleen, PAO, William, SHIH, Alan H, KUHN, John G

“…Purpose: We investigated the molecular effect of the epidermal growth factor receptor (EGFR) inhibitors erlotinib and gefitinib in vivo on all available tumors…”
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Two functional coding single nucleotide polymorphisms in STK15 (Aurora-A) coordinately increase esophageal cancer risk by KIMURA, Makoto T, MORI, Takahiro, CONROY, Jeffrey, NOWAK, Norma J, SATOMI, Susumu, TAMAI, Katsuyuki, NAGASE, Hiroki

“…STK15/Aurora-A is a serine/threonine kinase essential for chromosome segregation and cytokinesis, and is considered to be a cancer susceptibility gene in mice…”
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Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors by HACKETT, Christopher S, HODGSON, J. Graeme, JENKINS, Robert, GRAY, Joe W, WEISS, William A, LAW, Mark E, FRIDLYAND, Jane, OSOEGAWA, Kazutoyo, DE JONG, Pieter J, NOWAK, Norma J, PINKEL, Daniel, ALBERTSON, Donna G, JAIN, Ajay

“…Neuroblastoma, the third most common tumor of childhood, is a complex disease in which few genetic mutations have been identified.Mice expressing a human MYCN…”
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Array CGH analysis of pediatric medulloblastomas by Rossi, Michael R., Conroy, Jeffrey, McQuaid, Devin, Nowak, Norma J., Rutka, James T., Cowell, John K.

“…Brain tumors are the second most common childhood cancer. We used high‐resolution array comparative genomic hybridization (aCGH) to analyze losses and gains of…”
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Mapping segmental and sequence variations among laboratory mice using BAC array CGH by Snijders, Antoine M, Nowak, Norma J, Huey, Bing, Fridlyand, Jane, Law, Sindy, Conroy, Jeffrey, Tokuyasu, Taku, Demir, Kubilay, Chiu, Readman, Mao, Jian-Hua, Jain, Ajay N, Jones, Steven J M, Balmain, Allan, Pinkel, Daniel, Albertson, Donna G

“…We used arrays of 2069 BACs (1303 nonredundant autosomal clones) to map sequence variation among Mus spretus (SPRET/Ei and SPRET/Glasgow) and Mus musculus…”
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Novel amplicons on the short arm of chromosome 7 identified using high resolution array CGH contain over expressed genes in addition to EGFR in glioblastoma multiforme by Rossi, Michael R., La Duca, Jeffrey, Matsui, Sei-Ichi, Nowak, Norma J., Hawthorn, Lesleyann, Cowell, John K.

“…Amplification of a defined chromosome segment on the short arm of chromosome 7 has frequently been reported in glioblastoma multiforme (GBM), where it is…”
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Characterization of the 1p/19q Chromosomal Loss in Oligodendrogliomas Using Comparative Genomic Hybridization Arrays (CGHa) by Cowell, John K, Barnett, Gene H, Nowak, Norma J

“…ABSTRACTLoss of genetic material from the short arm of chromosome 1 and the long arm of chromosome 19 in anaplastic oligodendrogliomas has been shown to…”
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Screening of 24 chromosomes in single cells using microarray comparative genomic hybridization methods: implications for preimplantation genetic diagnosis by Steuerwald, NM, Wells, D, Nowak, NJ, Cohen, J, Munné, S

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High-Resolution Analysis of Genetic Events in Cancer Cells Using Bacterial Artificial Chromosome Arrays and Comparative Genome Hybridization by Cowell, John K., Nowak, Norma J.

“…Chromosome analysis of cancer cells has been one of the primary means of identifying key genetic events in the development of cancer. The relatively low…”
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Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome by Varon, Raymonda, Vissinga, Christine, Platzer, Matthias, Cerosaletti, Karen M, Chrzanowska, Krystyna H, Saar, Kathrin, Beckmann, Georg, Seemanová, Eva, Cooper, Paul R, Nowak, Norma J, Stumm, Markus, Weemaes, Corry M.R, Gatti, Richard A, Wilson, Richard K, Digweed, Martin, Rosenthal, André, Sperling, Karl, Concannon, Patrick, Reis, André

“…Nijmegen breakage syndrome (NBS) is an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation,…”
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Identification and characterisation of constitutional chromosome abnormalities using arrays of bacterial artificial chromosomes by COWELL, J. K, WANG, Y. D, HEAD, K, CONROY, J, MCQUAID, D, NOWAK, N. J

“…Constitutional chromosome deletions and duplications frequently predispose to the development of a wide variety of cancers. We have developed a microarray of…”
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Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York by VARMA, G, VARMA, R, MOYSICH, K, FALKNER, K. L, GERADTS, J, HUANG, H, PRYSHCHEPAVA, A, GROTH, J, FLEMING, D, NOWAK, N. J, MCQUAID, D, CONROY, J, MAHONEY, M

“…High-resolution array comparative genomic hybridisation (aCGH) analysis of DNA copy number aberrations (CNAs) was performed on breast carcinomas in…”
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Identification of consistent novel submegabase deletions in low-grade oligodendrogliomas using array-based comparative genomic hybridization by Rossi, Michael R., Gaile, Daniel, LaDuca, Jeffrey, Matsui, Sei-Ichi, Conroy, Jeffrey, McQuaid, Devin, Chervinsky, David, Eddy, Roger, Chen, Hai-Shen, Barnett, Gene H., Nowak, Norma J., Cowell, John K.

“…We have analyzed 18 low‐grade gliomas using array comparative genomic hybridization (aCGH) with an average resolution of <500 kb. Because the majority of these…”
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In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells by Minderman, Hans, Conroy, Jeffrey M, O'Loughlin, Kieran L, McQuaid, Devin, Quinn, Paul, Li, Song, Pendyala, Lakshmi, Nowak, Norma J, Baer, Maria R

“…Objective: To study irinotecan (CPT-11)–induced changes in expression profiles of genes associated with cell cycle control and apoptosis in myeloid leukemia…”
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Genomic profiling of myeloid sarcoma by array comparative genomic hybridization by Deeb, George, Baer, Maria R., Gaile, Daniel P., Sait, Sheila N. Jani, Barcos, Maurice, Wetzler, Meir, Conroy, Jeffrey M., Nowak, Norma J., Cowell, John K., Cheney, Richard T.

“…Myeloid sarcoma (MS) is a tumor mass of myeloblasts or immature myeloid cells occurring in an extramedullary site. In this study, seven cases of MS [stomach…”
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Positional Cloning of a Gene Involved in Hereditary Multiple Exostoses by Wuyts, Wim, Van Hul, Wim, Wauters, Jan, Nemtsova, Marina, Reyniers, Edwin, Van Hul, Els, De Boulle, Kristel, de Vries, Bert B. A., Hendrickx, Jan, Herrygers, Ilde, Bossuyt, Paul, Balemans, Wendy, Fransen, Erik, Vits, Lieve, Coucke, Paul, Nowak, Norma J., Shows, Thomas B., Mallet, Laurence, van den Ouweland, Ans M. W., McGaughran, Julie, Halley, Dicky J. J., Willems, Patrick J.

“…Hereditary multiple exostosis (EXT) is an autosomal dominant condition mainly characterized by the presence of multiple exostoses on the long bones. These…”
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Intrachromosomal genomic instability in human sporadic colorectal cancer measured by genome-wide allelotyping and inter-(simple sequence repeat) PCR by ANDERSON, Garth R, BRENNER, Bruce M, JAHREIS, Gerald P, KAHLENBERG, Morton S, BASIK, Mark, SAIT, Sheila, RODRIGUEZ-BIGAS, Miguel A, NOWAK, Norma J, PETRELLI, Nicholas J, SHOWS, Thomas B, STOLER, Daniel L, SWEDE, Helen, NENG CHEN, HENRY, W. Michael, CONROY, Jeffrey M, KARPENKO, Matthew J, ISSA, Jean-Pierre, BARTOS, Jeremy D, BRUNELLE, Joslyn K

“…We have used genome-wide allelotyping with 348 polymorphic autosomal markers spaced, on average, 10 cM apart to quantitate the extent of intrachromosomal…”
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Double minute chromosomes in acute myeloid leukemia and myelodysplastic syndrome: Identification of new amplification regions by fluorescence in situ hybridization and spectral karyotyping by Sait, Sheila N.J., Qadir, Misbah U., Conroy, Jeffrey M., Matsui, Sei-Ichi, Nowak, Norma J., Baer, Maria R.

“…Double minute chromosomes (dmin) are small chromatin bodies consisting of genes amplified in an extrachromosomal location. dmins are uncommon in hematologic…”
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Regional myocardial perfusion after experimental subarachnoid hemorrhage by Zaroff, J G, Rordorf, G A, Titus, J S, Newell, J B, Nowak, N J, Torchiana, D F, Aretz, H T, Picard, M H, Macdonald, R L

“…The pathophysiology of cardiac injury after subarachnoid hemorrhage (SAH) remains controversial. Data from animal models suggest that catecholamine-mediated…”
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