Search Results - "Nowak, Mark W."

A digitally-modulated conductance clamp eliminates instability observed with larger current signals in conventional dynamic clamp by Costantino, Anthony, Nowak, Mark W., Korbel, Leigh, Kane, Alex, Bett, Glenna, Rasmusson, Randall L.

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Spectral properties of the voltage-sensitive dye di‑4-ANBDQBS by Panama, Brian K., Costantino, Anthony, Nowak, Mark W., Daddario, Andrew A., Rasmusson, Randall L., Bett, Glenna C.

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Input of expressed hERG current into a complex neuron in silico cardiac atrial cell: Implications for cardiotoxicity screening by Nowak, Mark W., Korbel, Leigh, Kane, Alex, Panama, Brian K., Hines, Michael L., Carnevale, Nicholas T., Bett, Glenna C., Rasmusson, Randall L.

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Water Permeability of C-Terminally Truncated Aquaporin 0 (AQP0 1-243) Observed in the Aging Human Lens by Ball, Lauren E, Little, Mark, Nowak, Mark W, Garland, Donita L, Crouch, Rosalie K, Schey, Kevin L

“…To first assess the distribution of posttranslationally truncated products of aquaporin 0 (AQP0) in dissected sections of a normal human lens and to determine…”
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Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors by Labarca, Cesar, Nowak, Mark W, Zhang, Haiyun, Tang, Lixin, Deshpande, Purnima, Lester, Henry A

“…In nicotinic acetylcholine receptors (nAChR), as well as glycine, GABAA (gamma-aminobutyric acid), serotonin (5-HT3), and GluCl glutamate receptors, a leucine…”
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Cloning and functional characterization of a second urea transporter from the kidney of the Atlantic stingray, Dasyatis sabina by Janech, Michael G, Fitzgibbon, Wayne R, Nowak, Mark W, Miller, Donald H, Paul, Richard V, Ploth, David W

“…The cloning of cDNAs encoding facilitated urea transporters (UTs) from the kidneys of the elasmobranchs indicates that in these fish renal urea reabsorption…”
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Molecular and functional characterization of a urea transporter from the kidney of the Atlantic stingray by Janech, Michael G, Fitzgibbon, Wayne R, Chen, Ruihua, Nowak, Mark W, Miller, Donald H, Paul, Richard V, Ploth, David W

“…In general, marine elasmobranch fishes (sharks, skates, and rays) maintain body fluid osmolality above seawater, principally by retaining large amounts of…”
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Real-time leak current correction using dynamic clamp for improved drug safety screening in stem cell-derived cardiomyocytes by Panama, Brian K., Nowak, Mark W., Franks, Brandon, Korbel, Leigh, Singh, Sanjot, Bett, Glenna C.L., Rasmusson, Randall L.

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Point Mutant Mice with Hypersensitive α4 Nicotinic Receptors Show Dopaminergic Deficits and Increased Anxiety by Labarca, Cesar, Schwarz, Johannes, Deshpande, Purnima, Schwarz, Sigrid, Nowak, Mark W., Fonck, Carlos, Nashmi, Raad, Kofuji, Paulo, Dang, Hong, Shi, Wenmei, Fidan, Melihat, Khakh, Baljit S., Chen, Zhoufeng, Bowers, Barbara J., Boulter, Jim, Wehner, Jeanne M., Lester, Henry A.

“…Knock-in mice were generated that harbored a leucine-to-serine mutation in the α4 nicotinic receptor near the gate in the channel pore. Mice with intact…”
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Identification of an alternatively processed nicotinic receptor α7 subunit RNA in mouse brain by Saragoza, Philip A, Modir, James G, Goel, Nidhi, French, Kristen L, Li, Li, Nowak, Mark W, Stitzel, Jerry A

“…The data in this report describe the discovery and characterization of a previously unidentified alternatively processed RNA for the neuronal nicotinic…”
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Oxidative stress and Ca2+ influx upregulate calpain and induce apoptosis in PC12 cells by RAY, S. K, FIDAN, M, NOWAK, M. W, WILFORD, G. G, HOGAN, E. L, BANIK, N. L

“…Calpain, a Ca2+-dependent cysteine protease, has previously been implicated in apoptosis or programmed cell death (PCD) in immune cells. Although oxidative…”
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Activator of G-protein signaling 1 blocks GIRK channel activation by a G-protein-coupled receptor: apparent disruption of receptor signaling complexes by Takesono, Aya, Nowak, Mark W, Cismowski, Mary, Duzic, Emir, Lanier, Stephen M

“…The Ras-related protein, activator of G-protein signaling 1 (AGS1) or Dexras1, interacts with G(i)/G(o)alpha and activates heterotrimeric G-protein signaling…”
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Nicotinic Receptor Binding Site Probed with Unnatural Amino Acid Incorporation in Intact Cells by Nowak, Mark W., Kearney, Patrick C., Sampson, Jeffrey R., Saks, Margaret E., Labarca, Cesar G., Silverman, Scott K., Zhong, Wenge, Thorson, Jon, Abelson, John N., Davidson, Norman, Schultz, Peter G., Dougherty, Dennis A., Lester, Henry A.

“…The nonsense codon suppression method for unnatural amino acid incorporation has been applied to intact cells and combined with electrophysiological analysis…”
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Ratiometry for improving the signal-to-noise with the red-shifted voltage dye di-4ANBDQBS by Costantino, Anthony, Panama, Brian K., Nowak, Mark W., Rasmusson, Randall L., Bett, Glenna

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Using real-time Ca2+ transients to drive “electronic expression” of Ca2+-dependent K+ currents using dynamic clamp by Panama, Brian K., Costantino, Anthony, Nowak, Mark W., Rasmusson, Randall L., Bett, Glenna

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Combining in-silico cardiac action potentials with HERG currents expressed in HEK cells using dynamic clamp in synthetic cell mode by Nowak, Mark W., Korbel, Leigh, Kane, Alex, Panama, Brian K., Bett, Glenna, Rasmusson, Randall L.

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Electronic Expression of Background and Delayed Rectifier Currents via Dynamic Clamp Produces Physiological Action Potentials in Stem Cell Derived Glutamatergic Neurons by Nowak, Mark W., Panama, Brian K., Korbel, Leigh, Rasmusson, Randall L., Bett, Glenna

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Molecular and functional characterization of a urea transporter from the kidney of a short-finned pilot whale by Janech, Michael G, Chen, Ruihua, Klein, Janet, Nowak, Mark W, McFee, Wayne, Paul, Richard V, Fitzgibbon, Wayne R, Ploth, David W

“…Cetaceans (whales and dolphins) always excrete urine with an osmolality markedly higher than that of plasma. Although the mechanisms by which cetaceans…”
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Low-Noise Fluorescent Infrared Detection of Single-Cell Cardiac Action Potentials by Costantino, Anthony, Panama, Brian K., Nowak, Mark W., Rasmusson, Randall L., Bett, Glenna

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Interfacing a real-time dynamic clamp system with neuron simulation software in living cells by Nowak, Mark W., Korbel, Leigh, Kane, Alex, Panama, Brian K., Hines, Michael, Carnevale, Nicholas T., Bett, Glenna C.L., Rasmusson, Randall L.

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