Search Results - "Nowak, Kristen L"

Apoptosis and autophagy in polycystic kidney disease (PKD) by Nowak, Kristen L., Edelstein, Charles L.

“…Apoptosis in the cystic epithelium is observed in most rodent models of polycystic kidney disease (PKD) and in human autosomal dominant PKD (ADPKD). Apoptosis…”
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Metformin Therapy in Autosomal Dominant Polycystic Kidney Disease: A Feasibility Study by Brosnahan, Godela M., Wang, Wei, Gitomer, Berenice, Struemph, Taylor, George, Diana, You, Zhiying, Nowak, Kristen L., Klawitter, Jelena, Chonchol, Michel B.

“…Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder that leads to kidney failure and has few treatment options. Metformin is…”
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IL-1 Inhibition and Vascular Function in CKD by Nowak, Kristen L, Chonchol, Michel, Ikizler, Talat Alp, Farmer-Bailey, Heather, Salas, Natjalie, Chaudhry, Rafia, Wang, Wei, Smits, Gerard, Tengesdal, Isak, Dinarello, Charles A, Hung, Adriana M

“…Vascular endothelial dysfunction and increased arterial stiffness contribute to increased cardiovascular risk in patients with CKD who exhibit chronic systemic…”
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Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease by Nowak, Kristen L, You, Zhiying, Gitomer, Berenice, Brosnahan, Godela, Torres, Vicente E, Chapman, Arlene B, Perrone, Ronald D, Steinman, Theodore I, Abebe, Kaleab Z, Rahbari-Oskoui, Frederic F, Yu, Alan S L, Harris, Peter C, Bae, Kyongtae T, Hogan, Marie, Miskulin, Dana, Chonchol, Michel

“…The association of overweight/obesity with disease progression in patients with autosomal dominant polycystic kidney disease (ADPKD) remains untested. We…”
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Vascular Function and Uric Acid-Lowering in Stage 3 CKD by Jalal, Diana I, Decker, Emily, Perrenoud, Loni, Nowak, Kristen L, Bispham, Nina, Mehta, Tapan, Smits, Gerard, You, Zhiying, Seals, Douglas, Chonchol, Michel, Johnson, Richard J

“…Hyperuricemia may contribute to endothelial dysfunction in CKD. We evaluated whether lowering serum uric acid levels with allopurinol improves endothelial…”
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Cholecalciferol, Calcitriol, and Vascular Function in CKD: A Randomized, Double-Blind Trial by Kendrick, Jessica, Andrews, Emily, You, Zhiying, Moreau, Kerrie, Nowak, Kristen L, Farmer-Bailey, Heather, Seals, Douglas R, Chonchol, Michel

“…High circulating vitamin D levels are associated with lower cardiovascular mortality in CKD, possibly by modifying endothelial function. We examined the effect…”
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Changes in tubular biomarkers with dietary intervention and metformin in patients with autosomal dominant polycystic kidney disease: a post-hoc analysis of two clinical trials by Wang, Wei, You, Zhiying, Steele, Cortney N, Gitomer, Berenice, Chonchol, Michel, Nowak, Kristen L

“…Tubular biomarkers, which reflect tubular dysfunction or injury, are associated with incident chronic kidney disease and kidney function decline. Several…”
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Dietary Sodium/Potassium Intake Does Not Affect Cognitive Function or Brain Imaging Indices by Nowak, Kristen L, Fried, Linda, Jovanovich, Anna, Ix, Joachim, Yaffe, Kristine, You, Zhiying, Chonchol, Michel

“…Dietary sodium may influence cognitive function through its effects on cerebrovascular function and cerebral blood flow. The aim of this study was to evaluate…”
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Mineralocorticoid Antagonism and Vascular Function in Early Autosomal Dominant Polycystic Kidney Disease: A Randomized Controlled Trial by Nowak, Kristen L., Gitomer, Berenice, Farmer-Bailey, Heather, Wang, Wei, Malaczewski, Mikaela, Klawitter, Jelena, You, Zhiying, George, Diana, Patel, Nayana, Jovanovich, Anna, Chonchol, Michel

“…Vascular dysfunction, characterized by impaired vascular endothelial function and increased large-elastic artery stiffness, is evident early in autosomal…”
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Examining the effects of uric acid-lowering on markers vascular of calcification and CKD-MBD; A post-hoc analysis of a randomized clinical trial by Andrews, Emily S, Perrenoud, Loni, Nowak, Kristen L, You, Zhiying, Pasch, Andreas, Chonchol, Michel, Kendrick, Jessica, Jalal, Diana

“…Chronic kidney disease (CKD)-mineral and bone disorder (MBD) is a systemic disorder that leads to vascular calcification and accelerated atherosclerosis. Uric…”
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Fibroblast Growth Factor 23 and the Risk of Infection-Related Hospitalization in Older Adults by Nowak, Kristen L, Bartz, Traci M, Dalrymple, Lorien, de Boer, Ian H, Kestenbaum, Bryan, Shlipak, Michael G, Garimella, Pranav S, Ix, Joachim H, Chonchol, Michel

“…Within monocytes, 1,25-dihydroxyvitamin D [1,25(OH) D] is important for production of cathelicidins, which in turn, are critical for antibacterial action…”
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Sex hormones and the risk of cardiovascular disease and mortality in male and female patients with chronic kidney disease: A systematic review and meta‐analysis by Oh, Ester S., Steele, Cortney N., You, Zhiying, Nowak, Kristen L., Jovanovich, Anna J.

“…Patients with chronic kidney disease (CKD) commonly experience sex hormone disturbances, which may be associated with the risk of cardiovascular disease (CVD)…”
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Metabolic Reprogramming in Autosomal Dominant Polycystic Kidney Disease: Evidence and Therapeutic Potential by Nowak, Kristen L, Hopp, Katharina

“…Autosomal dominant polycystic kidney disease is characterized by progressive development and enlargement of kidney cysts, leading to ESKD. Because the kidneys…”
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Drinking Water: The Saltier The Better? by Bispham, Nina Z, Nowak, Kristen L

“…See Article Naser et al…”
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Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease by Hopp, Katharina, Catenacci, Victoria A., Dwivedi, Nidhi, Kline, Timothy L., Wang, Wei, You, Zhiying, Nguyen, Dustin T., Bing, Kristen, Poudyal, Bhavya, Johnson, Ginger C., Jackman, Matthew R., Miller, Marsha, Steele, Cortney N., Serkova, Natalie J., MacLean, Paul S., Nemenoff, Raphael A., Gitomer, Berenice, Chonchol, Michel, Nowak, Kristen L.

“…Progression of autosomal dominant polycystic kidney disease (ADPKD) is modified by metabolic defects and obesity. Indeed, reduced food intake slows cyst growth…”
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Cerebrovascular pulsatility index is higher in chronic kidney disease by Oh, Ester S., Freeberg, Kaitlin A., Steele, Cortney N., Wang, Wei, Farmer‐Bailey, Heather, Coppock, McKinley E., Seals, Douglas R., Chonchol, Michel, Rossman, Matthew J., Craighead, Daniel H., Nowak, Kristen L.

“…Patients with chronic kidney disease (CKD) are more likely to die of cardiovascular diseases, including cerebrovascular disease, than to progress to end‐stage…”
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Curcumin therapy to treat vascular dysfunction in children and young adults with autosomal dominant polycystic kidney disease: Design and baseline characteristics of participants by Nowak, Kristen L., Farmer-Bailey, Heather, Cadnapaphornchai, Melissa A., You, Zhiying, George, Diana, Wang, Wei, Jovanovich, Anna, Soranno, Danielle E., Gitomer, Berenice, Chonchol, Michel

“…Although often considered to be a disease of adults, complications of autosomal dominant polycystic kidney disease (ADPKD) begin in childhood. While the…”
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Does inflammation affect outcomes in dialysis patients? by Nowak, Kristen L., Chonchol, Michel

“…Chronic, low‐grade inflammation is a common comorbid condition in chronic kidney disease (CKD), and particularly in chronic dialysis patients. In this review,…”
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Strategies for Achieving Healthy Vascular Aging by Nowak, Kristen L, Rossman, Matthew J, Chonchol, Michel, Seals, Douglas R

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Overweight and Obesity and Progression of ADPKD by Nowak, Kristen L, Steele, Cortney, Gitomer, Berenice, Wang, Wenchyi, Ouyang, John, Chonchol, Michel B

“…On the basis of earlier observations, we evaluated the association between overweight and obesity and rapid progression of autosomal dominant polycystic kidney…”
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