Search Results - "Nowak, Joanna I."
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Metabolic and Bioenergetic Alterations are Associated with Infection Susceptibility in Survivors of Severe Trauma: An Exploratory Study
Published in Shock (Augusta, Ga.) (01-11-2024)“…Trauma and blood loss are frequently associated with organ failure, immune dysfunction, and a high risk of secondary bacterial lung infections. We aim to test…”
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Protein Disulfide Isomerase Family A Member 3 Knockout Abrogate Effects of Vitamin D on Cellular Respiration and Glycolysis in Squamous Cell Carcinoma
Published in Nutrients (25-10-2023)“…PDIA3 is an endoplasmic reticulum disulfide isomerase, which is involved in the folding and trafficking of newly synthesized proteins. PDIA3 was also described…”
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Fibroblast Growth Factor Receptor Inhibitors Decrease Proliferation of Melanoma Cell Lines and Their Activity Is Modulated by Vitamin D
Published in International journal of molecular sciences (21-02-2024)“…Regardless of the unprecedented progress in malignant melanoma treatment strategies and clinical outcomes of patients during the last twelve years, this skin…”
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The Effects of Vitamin D on the Expression of IL-33 and Its Receptor ST2 in Skin Cells; Potential Implication for Psoriasis
Published in International journal of molecular sciences (29-11-2021)“…Interleukin 33 (IL-33) belongs to the IL-1 family and is produced constitutively by epithelial and endothelial cells of various organs, such as the skin. It…”
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FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs
Published in Cellular & molecular biology letters (14-05-2024)“…Genetic abnormalities in the FGFR signalling occur in 40% of breast cancer (BCa) patients resistant to anti-ER therapy, which emphasizes the potential of…”
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VDR and PDIA3 Are Essential for Activation of Calcium Signaling and Membrane Response to 1,25(OH)2D3 in Squamous Cell Carcinoma Cells
Published in Cells (Basel, Switzerland) (01-01-2024)“…The genomic activity of 1,25(OH)2D3 is mediated by vitamin D receptor (VDR), whilst non-genomic is associated with protein disulfide isomerase family A member…”
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Dissection of an impact of VDR and RXRA on the genomic activity of 1,25(OH)2D3 in A431 squamous cell carcinoma
Published in Molecular and cellular endocrinology (01-03-2024)“…BACKGROUNDHuman skin is the natural source, place of metabolism, and target for vitamin D3. The classical active form of vitamin D3, 1,25(OH)2D3, expresses…”
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Different impact of vitamin D on mitochondrial activity and morphology in normal and malignant keratinocytes, the role of genomic pathway
Published in Free radical biology & medicine (01-01-2024)“…Deregulation of mitochondria activity is one of the hallmarks of cancerogenesis and an important target for cancer therapy. Therefore, we compared the impact…”
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PDIA3 modulates genomic response to 1,25-dihydroxyvitamin D3 in squamous cell carcinoma of the skin
Published in Steroids (01-11-2023)“…An active form of vitamin D3 (1,25-dihydroxyvitamin D3) acts through vitamin D receptor (VDR) initiating genomic response, but several studies described also…”
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VDR and PDIA3 Are Essential for Activation of Calcium Signaling and Membrane Response to 1,25[sub.2]D[sub.3] in Squamous Cell Carcinoma Cells
Published in Cells (Basel, Switzerland) (01-12-2023)“…The genomic activity of 1,25(OH)[sub.2] D[sub.3] is mediated by vitamin D receptor (VDR), whilst non-genomic is associated with protein disulfide isomerase…”
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Dissection of an impact of VDR and RXRA on the genomic activity of 1,25(OH) 2 D 3 in A431 squamous cell carcinoma
Published in Molecular and cellular endocrinology (01-03-2024)“…Human skin is the natural source, place of metabolism, and target for vitamin D . The classical active form of vitamin D , 1,25(OH) D , expresses pluripotent…”
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VDR and PDIA3 Are Essential for Activation of Calcium Signaling and Membrane Response to 1,25(OH) 2 D 3 in Squamous Cell Carcinoma Cells
Published in Cells (Basel, Switzerland) (20-12-2023)“…The genomic activity of 1,25(OH) D is mediated by vitamin D receptor (VDR), whilst non-genomic is associated with protein disulfide isomerase family A member 3…”
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PDIA3 modulates genomic response to 1,25 - dihydroxyvitamin D 3 in squamous cell carcinoma of the skin
Published in Steroids (05-08-2023)“…An active form of vitamin D (1,25-dihydroxyvitamin D ) acts through vitamin D receptor (VDR) initiating genomic response, but several studies described also…”
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