Search Results - "Novotná, Barbora"

Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP) by Pimková Polidarová, Markéta, Břehová, Petra, Kaiser, Martin Maxmilian, Smola, Miroslav, Dračínský, Martin, Smith, Joshua, Marek, Aleš, Dejmek, Milan, Šála, Michal, Gutten, Ondrej, Rulíšek, Lubomír, Novotná, Barbora, Brázdová, Andrea, Janeba, Zlatko, Nencka, Radim, Boura, Evzen, Páv, Ondřej, Birkuš, Gabriel

“…Cyclic dinucleotides (CDNs) are second messengers that bind to the stimulator of interferon genes (STING) and trigger the expression of type I interferons and…”
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Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein by Smola, Miroslav, Gutten, Ondrej, Dejmek, Milan, Kožíšek, Milan, Evangelidis, Thomas, Tehrani, Zahra Aliakbar, Novotná, Barbora, Nencka, Radim, Birkuš, Gabriel, Rulíšek, Lubomír, Boura, Evzen

“…STING (stimulator of interferon genes) is a key regulator of innate immunity that has recently been recognized as a promising drug target. STING is activated…”
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Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations by Novotná, Barbora, Vaneková, Lenka, Zavřel, Martin, Buděšínský, Miloš, Dejmek, Milan, Smola, Miroslav, Gutten, Ondrej, Tehrani, Zahra Aliakbar, Pimková Polidarová, Markéta, Brázdová, Andrea, Liboska, Radek, Štěpánek, Ivan, Vavřina, Zdeněk, Jandušík, Tomáš, Nencka, Radim, Rulíšek, Lubomír, Bouřa, Evžen, Brynda, Jiří, Páv, Ondřej, Birkuš, Gabriel

“…Cyclic dinucleotides are second messengers in the cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) pathway, which plays an important role…”
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Enzymatic Synthesis of 3′–5′, 3′–5′ Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations by Novotná, Barbora, Holá, Lucie, Staś, Monika, Gutten, Ondrej, Smola, Miroslav, Zavřel, Martin, Vavřina, Zdeněk, Buděšínský, Miloš, Liboska, Radek, Chevrier, Florian, Dobiaš, Juraj, Boura, Evzen, Rulíšek, Lubomír, Birkuš, Gabriel

“…The 3′–5′, 3′–5′ cyclic dinucleotides (3′3′CDNs) are bacterial second messengers that can also bind to the stimulator of interferon genes (STING) adaptor…”
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Evaluation of Cytotoxicity of the Dental Materials TheraCal LC, TheraCal PT, ApaCal ART and Biodentine Used in Vital Pulp Therapy: In Vitro Study by Novotná, Barbora, Holík, Pavel, Morozova, Yuliya, Rosa, Matej, Galandáková, Adéla, Langová, Kateřina

“…(1) Background: The aim of this study was to compare the cytotoxicity of selected resin-modified materials used in direct contact with the dental pulp…”
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The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against Enterococcus faecalis Bacterial Culture by Rosa, Matej, Morozova, Yuliya, Moštěk, Roman, Holík, Pavel, Somolová, Lucia, Novotná, Barbora, Zábojníková, Soňa, Bogdanová, Kateřina, Langová, Kateřina, Voborná, Iva, Pospíšilová, Lenka, Kovařík, Josef Paul

“…(1) Background: Microorganisms originating from the microflora of the oral cavity are the main cause of the inflammatory diseases of the dental pulp and…”
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HIGHER EDUCATION FOR HIGHER COMPETITIVENESS by KOMÁREK, Jaroslav, DOČKAL, Jaroslav, MARKOVIČ, Peter, Barbora, NOVOTNÁ BŘEZOVSKÁ, RIGEL, Filip

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Self-Reported Overall Adherence and Correct Inhalation Technique Discordance in Chronic Obstructive Pulmonary Disease Population by Hendrychova, Tereza, Svoboda, Michal, Maly, Josef, Vlcek, Jiri, Zimcikova, Eva, Dvorak, Tomas, Zatloukal, Jaromir, Volakova, Eva, Plutinsky, Marek, Brat, Kristian, Popelkova, Patrice, Kopecky, Michal, Novotna, Barbora, Koblizek, Vladimir

“…Background: Adherence to inhaled medication constitutes a major problem in patients with chronic obstructive pulmonary disease (COPD) globally. However, large…”
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Real-life GOLD 2011 implementation: the management of COPD lacks correct classification and adequate treatment by Koblizek, Vladimir, Pecen, Ladislav, Zatloukal, Jaromir, Kocianova, Jana, Plutinsky, Marek, Kolek, Vitezslav, Novotna, Barbora, Kocova, Eva, Pracharova, Sarka, Tichopad, Ales

“…Chronic obstructive pulmonary disease (COPD) is a serious, yet preventable and treatable, disease. The success of its treatment relies largely on the proper…”
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Introducing a new prognostic instrument for long-term mortality prediction in COPD patients: the CADOT index by Brat, Kristian, Svoboda, Michal, Hejduk, Karel, Plutinsky, Marek, Zatloukal, Jaromir, Volakova, Eva, Popelkova, Patrice, Novotna, Barbora, Engova, Dita, Franssen, Frits M E, Vanfleteren, Lowie E G W, Spruit, Martijn A, Koblizek, Vladimir

“…The BODE (BMI, Obstruction - FEV , Dyspnoea - mMRC, Exercise - 6-MWT) and the ADO (Age, Dyspnoea - mMRC, Obstruction - FEV ) indices are widely used prognosis…”
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Breathing Out Completely Before Inhalation: The Most Problematic Step in Application Technique in Patients With Non-Mild Chronic Obstructive Pulmonary Disease by Vytrisalova, Magda, Hendrychova, Tereza, Touskova, Tereza, Zimcikova, Eva, Vlcek, Jiri, Nevoranek, Libor, Svoboda, Michal, Hejduk, Karel, Brat, Kristian, Plutinsky, Marek, Novotna, Barbora, Musilova, Pavlina, Cernohorsky, Matej, Koblizek, Vladimir

“…Patient adherence to an inhaled medication application technique (A-ApplT) represents a major health-care issue in patients with chronic obstructive pulmonary…”
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Chronic obstructive pulmonary disease prognostic score: A new index by Horita, Nobuyuki, Koblizek, Vladimir, Plutinsky, Marek, Novotna, Barbora, Hejduk, Karel, Kaneko, Takeshi

“…The evaluation of chronic obstructive pulmonary disease (COPD) has been shifting from spirometry to focus on the patients' overall health. Despite the…”
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Panelák jako symbol a místo paměti by Barbora Novotná

“…Tato esej se zabývá symbolickým významem českého "paneláku" pro lidi žijící v České republice. Autorka si klade tři otázky: Do jaké míry došlo k proměně jeho…”
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Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein by Smola, Miroslav, Gutten, Ondrej, Dejmek, Milan, Kožíšek, Milan, Evangelidis, Thomas, Tehrani, Zahra Aliakbar, Novotná, Barbora, Nencka, Radim, Birkuš, Gabriel, Rulíšek, Lubomír, Boura, Evzen

“…STING (stimulator of interferon genes) is a key regulator of innate immunity that has recently been recognized as a promising drug target. STING is activated…”
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Medicinal plants used by ‘root doctors’, local traditional healers in Bié province, Angola by Novotna, Barbora, Polesny, Zbynek, Pinto-Basto, Maria Fernanda, Van Damme, Patrick, Pudil, Petr, Mazancova, Jana, Duarte, Maria Cristina

“…This study is one of the first post-civil war efforts to document traditional botanical knowledge in Bié province, central Angola, in a first step to bring…”
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Lipid Nanoparticles for Broad‐Spectrum Nucleic Acid Delivery by Hejdankova, Zuzana, Vanek, Vaclav, Sedlak, Frantisek, Prochazka, Jan, Diederichs, Audrey, Kereïche, Sami, Novotna, Barbora, Budesinsky, Milos, Birkus, Gabriel, Grantz Saskova, Klara, Cigler, Petr

“…Lipid nanoparticles (LNPs) are the most advanced nonviral modality for nucleic acid (NA) delivery, and have recently gained enormous attention in the fields of…”
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Mutations in EXOSC2 are associated with a novel syndrome characterised by retinitis pigmentosa, progressive hearing loss, premature ageing, short stature, mild intellectual disability and distinctive gestalt by Di Donato, Nataliya, Neuhann, Teresa, Kahlert, Anne-Karin, Klink, Barbara, Hackmann, Karl, Neuhann, Irmingard, Novotna, Barbora, Schallner, Jens, Krause, Claudia, Glass, Ian A, Parnell, Shawn E, Benet-Pages, Anna, Nissen, Anke M, Berger, Wolfgang, Altmüller, Janine, Thiele, Holger, Weber, Bernhard H F, Schrock, Evelin, Dobyns, William B, Bier, Andrea, Rump, Andreas

“…Retinitis pigmentosa in combination with hearing loss can be a feature of different Mendelian disorders. We describe a novel syndrome caused by biallelic…”
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Prognostic Properties of the GOLD 2023 Classification System by Brat, Kristian, Svoboda, Michal, Zatloukal, Jaromir, Plutinsky, Marek, Volakova, Eva, Popelkova, Patrice, Novotna, Barbora, Dvorak, Tomas, Koblizek, Vladimir

“…Recently, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published an update on the Global Strategy for Prevention, Diagnosis and…”
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Deregulation of energetic metabolism in the clear cell renal cell carcinoma: A multiple pathway analysis based on microarray profiling by SOLTYSOVA, ANDREA, BREZA, JAN, TAKACOVA, MARTINA, FERUSZOVA, JANA, HUDECOVA, SONA, NOVOTNA, BARBORA, ROZBORILOVA, EVA, PASTOREKOVA, SILVIA, KADASI, LUDEVIT, KRIZANOVA, OLGA

“…Clear cell renal cell carcinoma (ccRCC) is the most frequent type of kidney cancer. In order to better understand the biology of ccRCC, we accomplished the…”
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A pilot data analysis of a metabolomic HPLC-MS/MS study of patients with COPD by Novotna, Barbora, Abdel-Hamid, Mohammed, Koblizek, Vladimir, Svoboda, Michal, Hejduk, Karel, Rehacek, Vit, Bis, Josef, Salajka, Frantisek

“…Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition with multiple clinical faces. Metabolomic profiling studies small molecules present…”
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