Search Results - "Novosadova, Maria"
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Uptitrating Treatment After Heart Failure Hospitalization Across the Spectrum of Left Ventricular Ejection Fraction
Published in Journal of the American College of Cardiology (06-06-2023)“…Acute heart failure (AHF) is associated with a poor prognosis regardless of left ventricular ejection fraction (LVEF). STRONG-HF showed the efficacy and safety…”
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Oral Treatment With α-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy
Published in Diabetes care (01-11-2006)“…Oral Treatment With α-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy The SYDNEY 2 trial Dan Ziegler , MD, FRCPE 1 , Alexander Ametov , MD 2 , Alexey…”
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Safety, tolerability and efficacy of up‐titration of guideline‐directed medical therapies for acute heart failure in elderly patients: A sub‐analysis of the STRONG‐HF randomized clinical trial
Published in European journal of heart failure (01-07-2023)“…Aims STRONG‐HF examined a high‐intensity care (HIC) strategy of rapid up‐titration of guideline‐directed medical therapy (GDMT) and close follow‐up after acute…”
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4
Corticosteroid burst therapy in patients with acute heart failure: Design of the CORTAHF pilot study
Published in ESC Heart Failure (01-10-2024)“…Aims Inflammation has emerged as a potential key pathophysiological mechanism in heart failure (HF) in general and acute HF (AHF) specifically, with…”
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Global differences in acute heart failure treatment: analysis of the STRONG‐HF site feasibility questionnaire
Published in ESC Heart Failure (01-08-2023)“…Aims Acute heart failure (AHF) has an impact on human health worldwide. Despite guidelines for treatment and management of AHF, mortality rates remain high…”
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Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial
Published in The Lancet (British edition) (03-12-2022)“…There is a paucity of evidence for dose and pace of up-titration of guideline-directed medical therapies after admission to hospital for acute heart failure…”
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Safety and efficacy of istaroxime in patients with acute heart failure‐related pre‐cardiogenic shock – a multicentre, randomized, double‐blind, placebo‐controlled, parallel group study (SEISMiC)
Published in European journal of heart failure (01-10-2022)“…Aims We examined the effects of istaroxime in patients hospitalized for acute heart failure (AHF) related Society for Cardiovascular Angiography and…”
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8
NT-proBNP and high intensity care for acute heart failure: the STRONG-HF trial
Published in European heart journal (14-08-2023)“…STRONG-HF showed that rapid up-titration of guideline-recommended medical therapy (GRMT), in a high intensity care (HIC) strategy, was associated with better…”
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9
Reduced congestion and improved response to a fluid/sodium challenge in chronic heart failure patients after initiation of sacubitril/valsartan: The NATRIUM‐HF study
Published in European journal of heart failure (01-07-2024)“…Aims The effects of initiating sacubitril/valsartan in patients with stable heart failure with reduced ejection fraction (HFrEF) on response to fluid and…”
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10
Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial
Published in Diabetes care (01-11-2006)“…The aim of this trial was to evaluate the effects of alpha-lipoic acid (ALA) on positive sensory symptoms and neuropathic deficits in diabetic patients with…”
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11
Sex‐specific analysis of the rapid up‐titration of guideline‐directed medical therapies after a hospitalization for acute heart failure: Insights from the STRONG‐HF trial
Published in European journal of heart failure (01-07-2023)“…Aims The aim of this study was to evaluate efficacy and safety of rapid up‐titration of guideline‐directed medical therapies (GDMT) in men and women…”
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12
Non‐cardiac comorbidities and intensive up‐titration of oral treatment in patients recently hospitalized for heart failure: Insights from the STRONG‐HF trial
Published in European journal of heart failure (01-11-2023)“…Aims To assess the potential interaction between non‐cardiac comorbidities (NCCs) and the efficacy and safety of high‐intensity care (HIC) versus usual care…”
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13
Effects of Rapid Uptitration of Neurohormonal Blockade on Effective, Sustainable Decongestion and Outcomes in STRONG-HF
Published in Journal of the American College of Cardiology (23-07-2024)“…Comprehensive uptitration of neurohormonal blockade targets fundamental mechanisms underlying development of congestion and may be an additional approach for…”
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14
Safety and Efficacy of Istaroxime 1.0 and 1.5 µg/kg/min for Patients With Pre-Cardiogenic Shock
Published in Journal of cardiac failure (01-07-2023)“…Istaroxime was shown, in a small study, to increase systolic blood pressure (SBP) in patients with pre-cardiogenic shock (CS) due to acute heart failure (AHF)…”
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15
Burst steroid therapy for acute heart failure: The CORTAHF randomized, open‐label, pilot trial
Published in European journal of heart failure (01-10-2024)“…ABSTRACT Aims Burst steroid therapy, effective in acute respiratory diseases, may benefit patients with acute heart failure (AHF) in whom inflammatory…”
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16
The Effects of Burst Steroid Therapy on Short-term Decongestion in Acute Heart Failure Patients With Pro-inflammatory Activation: A Post Hoc Analysis of the CORTAHF Randomized, Open-label, Pilot Trial
Published in Journal of cardiac failure (29-09-2024)“…•7-day prednisone therapy reduces congestion in patients with AHF and inflammation.•Prednisone treatment improves QoL in patients with AHF and high…”
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Safety Indicators in Patients Receiving High-intensity Care After Hospital Admission for Acute Heart Failure: The STRONG-HF Trial
Published in Journal of cardiac failure (01-04-2024)“…Safety, Tolerability and Efficacy of Rapid Optimization, Helped by NT-proBNP Testing, of Heart Failure Therapies (STRONG-HF) demonstrated the safety and…”
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Early changes in renal function during rapid up‐titration of guideline‐directed medical therapy following an admission for acute heart failure
Published in European journal of heart failure (01-12-2023)“…Aim In this subgroup analysis of STRONG‐HF, we explored the association between changes in renal function and efficacy of rapid up‐titration of…”
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Characteristics, treatment, and outcomes of early vs. late enrollees of the STRONG-HF trial
Published in The American heart journal (01-08-2024)“…The STRONG-HF trial showed that high-intensity care (HIC) consisting of rapid up-titration of guideline-directed medical therapy (GDMT) and close follow-up…”
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20
Biologically active adrenomedullin as a marker for residual congestion and early rehospitalization in patients hospitalized for acute heart failure: Data from STRONG‐HF
Published in European journal of heart failure (01-07-2024)“…Aims Biologically active adrenomedullin (bio‐ADM) is a promising marker of residual congestion. The STRONG‐HF trial showed that high‐intensity care (HIC) of…”
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