Search Results - "Novikov, Vyacheslav L."

Marine Polyhydroxynaphthoquinone, Echinochrome A: Prevention of Atherosclerotic Inflammation and Probable Molecular Targets by Artyukov, Aleksandr A, Zelepuga, Elena A, Bogdanovich, Larisa N, Lupach, Natalia M, Novikov, Vyacheslav L, Rutckova, Tatyana A, Kozlovskaya, Emma P

“…The effect of low doses of echinochrome A (EchA), a natural polyhydroxy-1,4-naphthoquinone pigment from the sea urchin , has been studied in clinical trials,…”
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The protective effects of echinochrome A structural analogs against oxidative stress and doxorubicin in AC16 cardiomyocytes by Yoon, Chang Shin, Kim, Hyoung Kyu, Mishchenko, Natalia P., Vasileva, Elena A., Fedoreyev, Sergey A., Shestak, Olga P., Balaneva, Nadezhda N., Novikov, Vyacheslav L., Stonik, Valentin A., Han, Jin

“…Backgrounds Echinochrome A (6-ethyl-2,3,5,7,8-pen-tahydroxy-1,4-naphthoquinone) is a common naphthoquinone pigment found in the shells, spines, and coelomic…”
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Preparative production of spinochrome E, a pigment of different sea urchin species by Shestak, Olga P, Anufriev, Victor Ph, Novikov, Vyacheslav L

“…A concise route to spinochrome E (1) (2,3,5,6,7,8-hexahydroxy-1,4-naphthoquinone), a pigment isolated from sea urchins of different species, has been developed…”
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Magnetic resonance imaging of mouse Ehrlich carcinoma growth inhibition by thiacarpine, an analogue of cytotoxic marine alkaloid polycarpine by Agafonova, Irina G, Radchenko, Oleg S, Novikov, Vyacheslav L, Aminin, Dmitry L, Stonik, Valentin A

“…Abstract The anticancer effect of thiacarpine, a synthetic analogue of the known cytotoxic alkaloid polycarpine isolated from the Pacific ascidian Polycarpa…”
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A simple and practical approach to the synthesis of the marine sponge pigment fascaplysin and related compounds by Radchenko, Oleg S., Novikov, Vyacheslav L., Elyakov, George B.

“…Fascaplysin 1 , an antimicrobial and cytotoxic red pigment of the marine sponge Fascaplys-inopsis sp., has been synthesized in five steps from tryptamine 2 in…”
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Synthesis of polycarpine, a cytotoxic sulfur-containing alkaloid from the ascidian Polycarpa aurata, and related compounds by Radchenko, Oleg S., Novikov, Vyacheslav L., Willis, Richard H., Murphy, Peter T., Elyakov, George B.

“…Polycarpine 1 , a highly cytotoxic marine natural product, has been synthesized in three steps from p-methoxyphenacyl bromide 4 in 57% overall yield. The key…”
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Inhibition of membrane transport ATPases by halenaquinol, a natural cardioactive pentacyclic hydroquinone from the sponge Petrosia seriata by Gorshkova, Irina A, Gorshkov, Boris A, Fedoreev, Sergey A, Shestak, Olga P, Novikov, Vyacheslav L, Stonik, Valentin A

“…Halenaquinol, a natural cardioactive pentacyclic hydroquinone from the sponge Petrosia seriata, was found to be a powerful inhibitor of the rat brainstem and…”
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Synthesis of (±)-Ploiariquinones A and B by Tchizhova, Alla Y, Anufriev, Victor P, Denisenko, Vladimir A, Novikov, Vyacheslav L

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Abnormal reactions of 2-methoxy-4,9-dimethyl-1-nitroacridine with selenous acid and selenium(IV) oxide. Synthesis of 1H-selenopheno[2,3,4-k,l]acridine-1-one: A new seleno-containing ring system by Radchenko, Oleg S., Sigida, Elena N., Balaneva, Nadezhda N., Dmitrenok, Pavel S., Novikov, Vyacheslav L.

“…Unusual course of the reaction was revealed on the oxidation of functionally substituted acridine containing the activated methyl groups by well‐known…”
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Abnormal reactions of 2‐methoxy‐4,9‐dimethyl‐1‐nitroacridine with selenous acid and selenium(IV) oxide. Synthesis of 1 H ‐selenopheno[2,3,4‐ k , l ]acridine‐1‐one: A new seleno‐containing ring system by Radchenko, Oleg S., Sigida, Elena N., Balaneva, Nadezhda N., Dmitrenok, Pavel S., Novikov, Vyacheslav L.

“…Unusual course of the reaction was revealed on the oxidation of functionally substituted acridine containing the activated methyl groups by well‐known…”
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A simple and effective approach to the synthesis of pyrido[4,3,2- mn]pyrrolo[3,2,1- de]acridine skeleton of arnoamines A and B, pentacyclic marine alkaloids from the ascidian Cystodytes sp by Radchenko, Oleg S., Balaneva, Nadezhda N., Denisenko, Vladimir A., Novikov, Vyacheslav L.

“…Starting from ethyl 5-hydroxy-2-methyl-1-phenylindole-3-carboxylate, a simple and effective approach to the synthesis of pyrido[4,3,2- mn]pyrrolo[3,2,1-…”
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Synthesis of some hydroxynaphthazarins and their cardioprotective effects under ischemia-reperfusion in vivo by Anufriey, Victor Ph, Novikov, Vyacheslav L., Maximov, Oleg B., Elyakov, George B., Levitsky, Dmitry O., Lebedev, Alexander V., Sadretdinov, Safa M., Shvilkin, Alexei V., Afonskaya, Natalya I., Ruda, Mikhail Ya, Cherpachenko, Nina M.

“…A series of hydroxynaphthazarins has been synthesized. Some of them were found in in vivo experiments to be protectors of myocardium under ischemia-reperfusion…”
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Fluoride salts-alcohols-alumina as reagents for nucleophilic substitution of chlorine atoms for alkoxy groups in 2,3-dichlorosubstituted juglones, naphthazarines, and quinizarines by Anufriev, Victor Ph, Novikov, Vyacheslav L.

“…Direct displacement of chlorine atoms by alkoxy groups in 2,3-dichlorosubstituted juglones (5-hydroxy-1,4-naphthoquinones), naphthazarines…”
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The Reductive Dehalogenation of Halo-Substituted Naphthazarins and Quinizarins as a Simple Route to Parent Compounds by Anufriev, Victor Ph, Malinovskaya, Galina V., Novikov, Vyacheslav L., Balanyova, Nadezhda N., Polonik, Sergey G.

“…By the reaction of 2-chloro-3-alkyl-, 2,3-dichloro(dibromo)-, trichloro-(tribromo)-and tetrachloro(tetrabromo)-naphthazarins and 2,3-dichloroquinizarin with…”
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A Convenient Method for the Selective Alkylation ofβ-OH Groups of 2(3)-Hydroxyjuglones and Hydroxynaphthazarines by Ph.Anufriev, Victor, Novikov, Vyacheslav L., Malinovskaya, Galina V., Glazunov, Valery P.

“…Trimethyl-and triethylorthoformates have been used for the selective alkylation of β-OH groups of 2(3)-hydroxy-3(2)-alkyljuglones, 2-hydroxy-3-alkyl-,…”
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