Search Results - "Novikov, Nikolai"

PD-1 blockade partially recovers dysfunctional virus-specific B cells in chronic hepatitis B infection by Salimzadeh, Loghman, Le Bert, Nina, Dutertre, Charles-A, Gill, Upkar S, Newell, Evan W, Frey, Christian, Hung, Magdeleine, Novikov, Nikolai, Fletcher, Simon, Kennedy, Patrick Tf, Bertoletti, Antonio

“…Chronic HBV (CHB) infection suppresses virus-specific T cells, but its impact on humoral immunity has been poorly analyzed. Here, we developed a dual-staining…”
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Pathological Correlates of Cognitive Decline in Parkinson’s Disease: From Molecules to Neural Networks by Novikov, Nikolai I., Brazhnik, Elena S., Kitchigina, Valentina F.

“…Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused by the death of dopaminergic neurons in the substantia nigra and appearance of…”
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The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM by Wong, Melanie H., Samal, Alexandra B., Lee, Mike, Vlach, Jiri, Novikov, Nikolai, Niedziela-Majka, Anita, Feng, Joy Y., Koltun, Dmitry O., Brendza, Katherine M., Kwon, Hyock Joo, Schultz, Brian E., Sakowicz, Roman, Saad, Jamil S., Papalia, Giuseppe A.

“…Calcium/calmodulin-dependent protein kinase II (CaMKII) is a multifunctional serine/threonine protein kinase that transmits calcium signals in various cellular…”
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Digital intelligent microclimate control of livestock farms by Ivanov, Yuri, Novikov, Nikolai

“…The article presents the livestock structural and hardware implementations, the element base of digital intelligent microclimate control’s systems, the tasks…”
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Impact of Primary Elvitegravir Resistance-Associated Mutations in HIV-1 Integrase on Drug Susceptibility and Viral Replication Fitness by ABRAM, Michael E, HLUHANICH, Rebecca M, SVAROVSKAIA, Evguenia S, MCCOLL, Damian J, WHITE, Kirsten L, MILLER, Michael D, GOODMAN, Derrick D, ANDREATTA, Kristen N, MARGOT, Nicolas A, LINDA YE, NIEDZIELA-MAJKA, Anita, BARNES, Tiffany L, NOVIKOV, Nikolai, XIAOWU CHEN

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Digital human factor management by Ivanov, Yuri, Voroshilov, Alexei, Novikov, Nikolai, Todradze, Konstantin

“…Now culture of manage safety, health and wellbeing in the mining industry needs a scientifically sound new approach to the training process for professionals…”
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Circulating HBsAg-specific B cells are partially rescued in chronically HBV-infected patients with functional cure by Gu, Shuqin, Tang, Libo, Guo, Ling, Zhong, Chunxiu, Fu, Xin, Ye, Guofu, Zhong, Shihong, Li, Xiaoyi, Wen, Chunhua, Zhou, Yang, Wei, Jinling, Chen, Haitao, Novikov, Nikolai, Fletcher, Simon P, Moody, M Anthony, Hou, Jinlin, Li, Yongyin

“…It is well established that humoral immunity targeting hepatitis B virus surface antigen (HBsAg) plays a critical role in viral clearance and clinical cure…”
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Joint Intratracheal Surfactant-Antibacterial Therapy in Experimental Pseudomonas-Induced Pneumonia by Birkun, Alexei A, Kubyshkin, Anatoly V, Novikov, Nikolai Y, Krivorutchenko, Yuri L, Fedosov, Michael I, Postnikova, Olga N, Snitser, Anatoly A

“…The application of an exogenous pulmonary surfactant as a carrier for intratracheally administered antimicrobials represents a promising therapeutic modality…”
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Intracardiac lipid accumulation, lipoatrophy of muscle cells and expansion of myocardial infarction in type 2 diabetic patients by Borisov, Andrei B., Ushakov, Alexei V., Zagorulko, Aleksandr K., Novikov, Nikolai Y., Selivanova, Ksenia F., Edwards, Chris A., Russell, Mark W.

“…The overall mortality of diabetic patients after myocardial infarction is 3–4 times higher than non-diabetics. The cellular mechanisms underlying such a poor…”
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Comparative characterization of B cells specific for HBV nucleocapsid and envelope proteins in patients with chronic hepatitis B by Le Bert, Nina, Salimzadeh, Loghman, Gill, Upkar Singh, Dutertre, Charles-Antoine, Facchetti, Floriana, Tan, Anthony, Hung, Magdeleine, Novikov, Nikolai, Lampertico, Pietro, Fletcher, Simon Paul, Kennedy, Patrick Thomas Francis, Bertoletti, Antonio

“…[Display omitted] •We developed a method for direct ex vivo visualization of HBV-specific B cells.•HBcAg- and HBsAg-specific B cells of patients with CHB…”
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Hepatitis B core-specific memory B cell responses associate with clinical parameters in patients with chronic HBV by Vanwolleghem, Thomas, Groothuismink, Zwier M.A., Kreefft, Kim, Hung, Magdeleine, Novikov, Nikolai, Boonstra, Andre

“…Little is known about the frequency, phenotype and function of HBV-specific B cells during chronic infection. Here we study HBcAg and HBsAg-specific B cells in…”
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A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model by Yant, Stephen R., Mulato, Andrew, Hansen, Derek, Tse, Winston C., Niedziela-Majka, Anita, Zhang, Jennifer R., Stepan, George J., Jin, Debi, Wong, Melanie H., Perreira, Jill M., Singer, Eric, Papalia, Giuseppe A., Hu, Eric Y., Zheng, Jim, Lu, Bing, Schroeder, Scott D., Chou, Kevin, Ahmadyar, Shekeba, Liclican, Albert, Yu, Helen, Novikov, Nikolai, Paoli, Eric, Gonik, Daniel, Ram, Renee R., Hung, Magdeleine, McDougall, William M., Brass, Abraham L., Sundquist, Wesley I., Cihlar, Tomas, Link, John O.

“…People living with HIV (PLWH) have expressed concern about the life-long burden and stigma associated with taking pills daily and can experience medication…”
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Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ by Somoza, John R., Koditek, David, Villaseñor, Armando G., Novikov, Nikolai, Wong, Melanie H., Liclican, Albert, Xing, Weimei, Lagpacan, Leanna, Wang, Ruth, Schultz, Brian E., Papalia, Giuseppe A., Samuel, Dharmaraj, Lad, Latesh, McGrath, Mary E.

“…Idelalisib (also known as GS-1101, CAL-101, IC489666, and Zydelig) is a PI3Kδ inhibitor that has recently been approved for the treatment of several…”
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New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action by Tsiang, Manuel, Jones, Gregg S., Niedziela-Majka, Anita, Kan, Elaine, Lansdon, Eric B., Huang, Wayne, Hung, Magdeleine, Samuel, Dharmaraj, Novikov, Nikolai, Xu, Yili, Mitchell, Michael, Guo, Hongyan, Babaoglu, Kerim, Liu, Xiaohong, Geleziunas, Romas, Sakowicz, Roman

“…tert-Butoxy-(4-phenyl-quinolin-3-yl)-acetic acids (tBPQA) are a new class of HIV-1 integrase (IN) inhibitors that are structurally distinct from IN strand…”
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Differential changes in global and antigen-specific B cell frequencies and function associate with the outcome of HBV nucleos (t)ide analog treatment withdrawal by Lens, Sabela, Burton, Alice, Davies, Jessica, García-López, Mireia, Jeffery-Smith, Anna, Novikov, Nikolai, Fletcher, Simon, Pérez-del-Pulgar, Sofía, Forns, Xavier, Maini, Mala

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FRI-153-Potent hepatitis B core-specific B cell responses associate with clinical parameters in untreated and virally suppressed chronic HBV patients by Vanwolleghem, Thomas, Grooshuismink, Anthony, Kreefft, Kim, Hung, Magdeleine, Novikov, Nikolai, Boonstra, Andre

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Long Dissociation of Bictegravir from HIV-1 Integrase-DNA Complexes by White, Kirsten L, Osman, Nathan, Cuadra-Foy, Ernesto, Brenner, Bluma G, Shivakumar, Devleena, Campigotto, Federico, Tsiang, Manuel, Morganelli, Philip A, Novikov, Nikolai, Lazerwith, Scott E, Jin, Haolun, Niedziela-Majka, Anita

“…The HIV integrase (IN) strand transfer inhibitor (INSTI) bictegravir (BIC) has a long dissociation half-life (t ) from wild-type IN-DNA complexes: BIC 163 hr >…”
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Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection by Burdette, Dara, Hyrina, Anastasia, Song, Zhijuan, Beran, Rudolf K, Cheung, Tara, Gilmore, Sarah, Kobayashi, Tetsuya, Li, Li, Liu, Yang, Niedziela-Majka, Anita, Medley, Jonathan, Mehra, Upasana, Morganelli, Philip, Novikov, Nikolai, Niu, Congrong, Tam, Danny, Tang, Jennifer, Wang, Jianhong, Yue, Qin, Fletcher, Simon P, Holdorf, Meghan M, Delaney, 4th, William E, Feierbach, Becket, Lazerwith, Scott

“…The standard of care for the treatment of chronic hepatitis B (CHB) is typically lifelong treatment with nucleos(t)ide analogs (NAs), which suppress viral…”
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PD-1 blockade partially recovers dysfunctional virus–specific B cells in chronic hepatitis B infection by Salimzadeh, Loghman, Bert, Nina Le, Dutertre, Charles-A, Gill, Upkar S, Newell, Evan W, Frey, Christian, Hung, Magdeleine, Novikov, Nikolai, Fletcher, Simon, Kennedy, Patrick T F, Bertoletti, Antonio

“…Chronic HBV (CHB) infection suppresses virus-specific T cells, but its impact on humoral immunity has been poorly analyzed. Here, we developed a dual-staining…”
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2,4,6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective Inhibitors by Patel, Leena, Chandrasekhar, Jayaraman, Evarts, Jerry, Haran, Aaron C, Ip, Carmen, Kaplan, Joshua A, Kim, Musong, Koditek, David, Lad, Latesh, Lepist, Eve-Irene, McGrath, Mary E, Novikov, Nikolai, Perreault, Stephane, Puri, Kamal D, Somoza, John R, Steiner, Bart H, Stevens, Kirk L, Therrien, Joseph, Treiberg, Jennifer, Villaseñor, Armando G, Yeung, Arthur, Phillips, Gary

“…Inhibition of phosphoinositide 3-kinase δ (PI3Kδ) is an appealing target for several hematological malignancies and inflammatory diseases. Herein, we describe…”
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