Search Results - "Novello, J. C."

Renal toxicity of Bothrops moojeni snake venom and its main myotoxins by Barbosa, P.S.F, Havt, A, Facó, P.E.G, Sousa, T.M, Bezerra, I.S.A.M, Fonteles, M.C, Toyama, M.H, Marangoni, S, Novello, J.C, Monteiro, H.S.A

“…Acute renal failure is one the most common systemic complications after snakebite, however, its pathogenesis remains obscure. In this study we evaluated the…”
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Neurotoxic and myotoxic actions of crotoxin-like and Crotalus durissus cascavella whole venom in the chick biventer cervicis preparation by Beghini, Daniela G, Rodrigues-Simioni, Léa, Toyama, M.H, Novello, J.C, da Cruz-Höfling, Maria Alice, Marangoni, S

“…Crotoxin from Crotalus durissus cascavella venom was purified by a combination of molecular exclusion chromatography (Superdex 75 column) and HPLC molecular…”
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Isolation and preliminary enzymatic characterization of a novel PLA2 from Crotalus durissus collilineatus venom by Ponce-Soto, L A, Toyama, M H, Hyslop, S, Novello, J C, Marangoni, S

“…A crotoxin homolog was purified from the Crotalus durissus collilineatus venom using molecular exclusion and reverse-phase HPLC. This crotoxin contained one…”
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Trypsin inhibitor from Dimorphandra mollis seeds: purification and properties by Macedo, Maria Lı́gia R., de Matos, Daniela Gaspar G., Machado, Olga L.T., Marangoni, Sérgio, Novello, José C.

“…A trypsin inhibitor from Dimorphandra mollis seeds was isolated to apparent homogeneity by a combination of ammonium sulfate precipitation, gel filtration,…”
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Structural and functional characterization of basic PLA2 isolated from Crotalus durissus terrificus venom by Oliveira, D G, Toyama, M H, Novello, J C, Beriam, L O S, Marangoni, S

“…The venom of Crotalus durissus terrificus was fractionated by reverse-phase HPLC to obtain crotapotins (F5 and F7) and PLA2 (F15, F16, and F17) of high purity…”
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Isolation and characterization of a lectin from Annona muricata seeds by Damico, D C S, Freire, M G M, Gomes, V M, Toyama, M H, Marangoni, S, Novello, J C, Macedo, M L R

“…A lectin with a high affinity for glucose/mannose was isolated from Annona muricata seeds (Annonaceae) by gel filtration chromatography on Sephacryl S-200, ion…”
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Biochemical characterization and N-terminal sequences of two new trypsin inhibitors from Copaifera langsdorffii seeds by Silva, J A, Macedo, M L, Novello, J C, Marangoni, S

“…Two new trypsin inhibitors, TDI-I and TDI-II, were purified from the seeds of the native Brazilian tree Copaifera langsdorffii (Caesalpinoideae, Leguminosae)…”
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Isolation and enzymatic characterization of a basic phospholipase A2 from Bothrops jararacussu snake venom by Bonfim, V L, Toyama, M H, Novello, J C, Hyslop, S, Oliveira, C R, Rodrigues-Simioni, L, Marangoni, S

“…A novel basic phospholipase A2 (PLA2) isoform was isolated from Bothrops jararacussu snake venom and partially characterized. The venom was fractionated by…”
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A new method to purify hepatic CYP1A of Prochilodus scrofa, a Brazilian freshwater fish by Da Silva, M.E.F, Silva, J.A, Marangoni, S, Novello, J.C, Meirelles, N.C

“…Cytochromes P450 constitute a superfamily of the phase I enzymes whose primary task is the detoxification of both endogenous and xenobiotic compounds. Fish,…”
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Purification and partial characterization of a thrombin-like enzyme, balterobin, from the venom of Bothrops alternatus by Smolka, Marcus B., Marangoni, Sérgio, Oliveira, Benedito, Novello, José C.

“…A thrombin-like enzyme, balterobin, was purified from the venom of Bothrops alternatus. The purification steps included Sephadex G-75, heparin–sepharose and…”
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Biochemical characterization of a lectin from Delonix regia seeds by Pando, S C, Macedo, M L R, Freire, M G M, Toyama, M H, Novello, J C, Marangoni, S

“…A lectin from Delonix regia (DRL) seeds was purified by gel filtration on Sephadex G-100 followed by ion-exchange chromatography on diethylaminoethyl-Sepharose…”
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Enzymatic characterization of a novel phospholipase A2 from Crotalus durissus cascavella rattlesnake (Maracambóia) venom by Beghini, D G, Toyama, M H, Hyslop, S, Sodek, L, Novello, J C, Marangoni, S

“…The PLA2 and crotapotin subunits of crotoxin from Crotalus durissus cascavella venom were purified by a combination of HPLC molecular exclusion (Protein Pack…”
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The amino acid sequence of bothropstoxin-II, an Asp-49 myotoxin from Bothrops jararacussu (Jararacucu) venom with low phospholipase A2 activity by Pereira, M F, Novello, J C, Cintra, A C, Giglio, J R, Landucci, E T, Oliveira, B, Marangoni, S

“…The complete amino acid sequence of bothropstoxin-II (BthTX-II), a myotoxin isolated from Bothrops jararacussu snake venom, is reported. The results show that…”
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TsTX-IV, a short chain four-disulfide-bridged neurotoxin from Tityus serrulatus venom which acts on Ca2+-activated K+ channels by NOVELLO, J. C, ARANTES, E. C, VARANDA, W. A, OLIVEIRA, B, GIGLIO, J. R, MARANGONI, S

“…The primary structure of TsTX-IV, a neurotoxin isolated from Tityrus serrulatus scorpion venom, is reported. Its amino acid sequence was determined by…”
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Mitochondrial swelling and oxygen consumption during respiratory state 4 induced by phospholipase A2 isoforms isolated from the south American rattlesnake (Crotalus durissus terrificus) venom by VALENTE, R. H, NOVELLO, J. C, MARANGONI, S, OLIVEIRA, B, PEREIRA-DA-SILVA, L, MACEDO, D. V

“…The non-covalent interaction between two molecular entities namely, phospholipase A2 and crotapotin, results in the main toxin, crotoxin, present in the venom…”
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Crotoxin induces aggregation of human washed platelets by Landucci, E C, Condino-Neto, A, Perez, A C, Hyslop, S, Corrado, A P, Novello, J C, Marangoni, S, Oliveira, B, Antunes, E, de Nucci, G

“…Crotoxin, the main toxic component isolated from the venom of the South American rattlesnake Crotalus durissus terrificus, is a reversible protein complex…”
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Isolation and partial characterization of a polypeptide from Phoneutria nigriventer spider venom that relaxes rabbit corpus cavernosum in vitro by Rego, E., Bento, A.C., B.-Lopes-Martins, R.A., Antunes, E., Novello, J.C., Marangoni, S., Giglio, J.R., Oliveira, B., De Nucci, G.

“…The venom of the Brazilian spider Phoneutria nigriventer was fractionated using a C18 μBondapack reverse-phase high-performance liquid chromatography column…”
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Purification, crystallization and preliminary crystallographic study of a Kunitz-type trypsin inhibitor from Delonix regia seeds by Polikarpov, I., Golubev, A. M., Perles, L. A., Pando, S. C., Novello, J. C., Marangoni, S.

“…The Kunitz‐type trypsin inhibitor from seeds of Flamboyant (Delonix regia) has been purified to homogeneity and plate‐like crystals suitable for X‐ray analysis…”
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Isolation and characterization of a serine protease, Ba III-4, from Peruvian Bothrops atrox venom by Ponce-Soto, L A, Bonfim, V L, Novello, J C, Navarro Oviedo, R, Yarlequé Chocas, A, Marangoni, S

“…A serine protease from Bothrops atrox (Peruvian specimen's venom) was isolated in two chromatographic steps in LC molecular exclusion and reverse phase-HPLC…”
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HSP72 as a complementary protection against oxidative stress induced by exercise in the soleus muscle of rats by Smolka, M B, Zoppi, C C, Alves, A A, Silveira, L R, Marangoni, S, Pereira-Da-Silva, L, Novello, J C, Macedo, D V

“…Given the potential of reactive oxygen species to damage intracellular proteins during subsequent bouts of muscle contractions, it was suggested that, when…”
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