Search Results - "Novellis, Vito de"

5'-Chloro-5'-deoxy-(±)-ENBA, a Potent and Selective Adenosine A1 Receptor Agonist, Alleviates Neuropathic Pain in Mice Through Functional Glial and Microglial Changes without Affecting Motor or Cardiovascular Functions by Luongo, Livio, Petrelli, Riccardo, Gatta, Luisa, Giordano, Catia, Guida, Francesca, Vita, Patrizia, Franchetti, Palmarisa, Grifantini, Mario, Novellis, Vito de, Cappellacci, Loredana, Maione, Sabatino

“…This study was undertaken in order to investigate the effect of chronic treatment with 5′-chloro-5′-deoxy-(±)-ENBA, a potent and highly selective agonist of…”
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Moving towards Supraspinal TRPV1 Receptors for Chronic Pain Relief by Palazzo, Enza, Luongo, Livio, de Novellis, Vito, Berrino, Liberato, Rossi, Francesco, Maione, Sabatino

“…Transient receptor potential vanilloid type 1 (TRPV1) receptor is a non selective ligand-gated cation channel activated by capsaicin, heat, protons and…”
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Salvinorin A Reduces Mechanical Allodynia and Spinal Neuronal Hyperexcitability Induced by Peripheral Formalin Injection by Guida, Francesca, Luongo, Livio, Aviello, Gabriella, Palazzo, Enza, De Chiaro, Maria, Gatta, Luisa, Boccella, Serena, Marabese, Ida, Zjawiony, Jordan K, Capasso, Raffaele, Izzo, Angelo A, de Novellis, Vito, Maione, Sabatino

“…Background: Salvinorin A (SA), the main active component of Salvia Divinorum, is a non-nitrogenous kappa opioid receptor (KOR) agonist. It has been shown to…”
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The Blockade of the Transient Receptor Potential Vanilloid Type 1 and Fatty Acid Amide Hydrolase Decreases Symptoms and Central Sequelae in the Medial Prefrontal Cortex of Neuropathic Rats by de Novellis, Vito, Vita, Daniela, Gatta, Luisa, Luongo, Livio, Bellini, Giulia, De Chiaro, Maria, Marabese, Ida, Siniscalco, Dario, Boccella, Serena, Piscitelli, Fabiana, Di Marzo, Vincenzo, Palazzo, Enza, Rossi, Francesco, Maione, Sabatino

“…Background: Neuropathic pain is a chronic disease resulting from dysfunction within the “pain matrix”. The basolateral amygdala (BLA) can modulate cortical…”
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The Role of Cannabinoid Receptors in the Descending Modulation of Pain by Palazzo, Enza, Luongo, Livio, Novellis, Vito de, Rossi, Francesco, Maione, Sabatino

“…The endogenous antinociceptive descending pathway represents a circuitry of the supraspinal central nervous system whose task is to counteract pain. It…”
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Behavioral, Biochemical and Electrophysiological Changes in Spared Nerve Injury Model of Neuropathic Pain by Guida, Francesca, De Gregorio, Danilo, Palazzo, Enza, Ricciardi, Flavia, Boccella, Serena, Belardo, Carmela, Iannotta, Monica, Infantino, Rosmara, Formato, Federica, Marabese, Ida, Luongo, Livio, de Novellis, Vito, Maione, Sabatino

“…Neuropathic pain is a pathological condition induced by a lesion or disease affecting the somatosensory system, with symptoms like allodynia and hyperalgesia…”
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Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain by Boccella, Serena, Guida, Francesca, De Logu, Francesco, De Gregorio, Danilo, Mazzitelli, Mariacristina, Belardo, Carmela, Iannotta, Monica, Serra, Nicola, Nassini, Romina, Novellis, Vito, Geppetti, Pierangelo, Maione, Sabatino, Luongo, Livio

“…ABSTRACT The mechanisms underlying neuropathic pain are poorly understood. Here we show the unexplored role of the hydroxyl carboxylic acid receptor type 2…”
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Nociception modulation by supraspinal group III metabotropic glutamate receptors by Palazzo, Enza, Marabese, Ida, Luongo, Livio, Guida, Francesca, Novellis, Vito, Maione, Sabatino

“…The modulatory actions of glutamate, the main excitatory neurotransmitter in the central nervous system (CNS), are exerted through the activation of…”
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Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity by Sacchi, Silvia, Novellis, Vito De, Paolone, Giovanna, Nuzzo, Tommaso, Iannotta, Monica, Belardo, Carmela, Squillace, Marta, Bolognesi, Paolo, Rosini, Elena, Motta, Zoraide, Frassineti, Martina, Bertolino, Alessandro, Pollegioni, Loredano, Morari, Michele, Maione, Sabatino, Errico, Francesco, Usiello, Alessandro

“…D-aspartate levels in the brain are regulated by the catabolic enzyme D-aspartate oxidase (DDO). D-aspartate activates NMDA receptors, and influences brain…”
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Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway by Boccella, Serena, Cristiano, Claudia, Romano, Rosaria, Iannotta, Monica, Belardo, Carmela, Farina, Antonio, Guida, Francesca, Piscitelli, Fabiana, Palazzo, Enza, Mazzitelli, Mariacristina, Imperatore, Roberta, Tunisi, Lea, de Novellis, Vito, Cristino, Luigia, Di Marzo, Vincenzo, Calignano, Antonio, Maione, Sabatino, Luongo, Livio

“…Chronic pain is associated with cognitive deficits. Palmitoylethanolamide (PEA) has been shown to ameliorate pain and pain-related cognitive impairments by…”
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Supraspinal metabotropic glutamate receptors: a target for pain relief and beyond by Palazzo, Enza, Marabese, Ida, de Novellis, Vito, Rossi, Francesco, Maione, Sabatino

“…Glutamate is the main excitatory neurotransmitter in the central nervous system, controlling the majority of synapses. Apart from neurodegenerative diseases,…”
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Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging by Punzo, Daniela, Errico, Francesco, Cristino, Luigia, Sacchi, Silvia, Keller, Simona, Belardo, Carmela, Luongo, Livio, Nuzzo, Tommaso, Imperatore, Roberta, Florio, Ermanno, De Novellis, Vito, Affinito, Ornella, Migliarini, Sara, Maddaloni, Giacomo, Sisalli, Maria Josè, Pasqualetti, Massimo, Pollegioni, Loredano, Maione, Sabatino, Chiariotti, Lorenzo, Usiello, Alessandro

“…The endogenous NMDA receptor (NMDAR) agonist D-aspartate occurs transiently in the mammalian brain because it is abundant during embryonic and perinatal phases…”
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Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice by Luongo, Livio, Guida, Francesca, Boccella, Serena, Bellini, Giulia, Gatta, Luisa, Rossi, Francesca, de Novellis, Vito, Maione, Sabatino

“…Palmitoylethanolamide (PEA) is an endogenous cannabinoid-like compound in the central nervous system, which can modulate several functions in different…”
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Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats by Petrosino, Stefania, Palazzo, Enza, de Novellis, Vito, Bisogno, Tiziana, Rossi, Francesco, Maione, Sabatino, Di Marzo, Vincenzo

“…Recent studies have shown that activation of the cannabinoid CB 1 receptor by synthetic agonists, and pharmacological elevation of endocannabinoid levels,…”
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Metabotropic Glutamate Receptor 7: From Synaptic Function to Therapeutic Implications by Palazzo, Enza, Marabese, Ida, de Novellis, Vito, Rossi, Francesco, Maione, Sabatino

“…Metabotropic glutamate receptor 7 (mGluR7) is localized presynaptically at the active zone of neurotransmitter release. Unlike mGluR4 and mGluR8, which share…”
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Metabotropic glutamate receptor subtype 8 in the amygdala modulates thermal threshold, neurotransmitter release, and rostral ventromedial medulla cell activity in inflammatory pain by Palazzo, Enza, Marabese, Ida, Soukupova, Marie, Luongo, Livio, Boccella, Serena, Giordano, Catia, de Novellis, Vito, Rossi, Francesca, Maione, Sabatino

“…The amygdala is a crucial area in controlling the threshold of pain and its emotional component. The present study has evaluated the effect of a metabotropic…”
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2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors by Boccella, Serena, Guida, Francesca, Iannotta, Monica, Iannotti, Fabio Arturo, Infantino, Rosmara, Ricciardi, Flavia, Cristiano, Claudia, Vitale, Rosa Maria, Amodeo, Pietro, Marabese, Ida, Belardo, Carmela, de Novellis, Vito, Paino, Salvatore, Palazzo, Enza, Calignano, Antonio, Di Marzo, Vincenzo, Maione, Sabatino, Luongo, Livio

“…Neuropathic pain (NP) remains an untreatable disease due to the complex pathophysiology that involves the whole pain neuraxis including the forebrain. Sensory…”
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Effect of Prolonged Moderate Exercise on the Changes of Nonneuronal Cells in Early Myocardial Infarction by Rossi, Francesco, De Novellis, Vito, Maione, Sabatino, Urbanek, Konrad, Gritti, Giulia, Luongo, Livio, Donniacuo, Maria, Furiano, Anna, Guida, Francesca, Rinaldi, Barbara, Messina, Giovanni

“…Myocardial infarction (MI) is one of the leading causes of death in developed countries and it is characterized by several associated symptomatologies and poor…”
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Endogenous modulators of TRP channels by Palazzo, Enza, Rossi, Francesco, de Novellis, Vito, Maione, Sabatino

“…The transient receptor potential (TRP) superfamily consists of a large number of cation channels permeable to both monovalent and divalent cations. The 28…”
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Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors by Maione, Sabatino, Bisogno, Tiziana, de Novellis, Vito, Palazzo, Enza, Cristino, Luigia, Valenti, Marta, Petrosino, Stefania, Guglielmotti, Vittorio, Rossi, Francesco, Di Marzo, Vincenzo

“…In the ventrolateral periaqueductal gray (PAG), activation of excitatory output neurons projecting monosynaptically to OFF cells in the rostral ventromedial…”
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