Search Results - "Novellino, Ettore"

Nutraceuticals: A paradigm of proactive medicine by Santini, Antonello, Tenore, Gian Carlo, Novellino, Ettore

“…Nutraceuticals define a new category which shades the frontier between drugs and food. As per its definition, a nutraceutical is “a food or part of a food that…”
Get full text

Nutraceuticals: opening the debate for a regulatory framework by Santini, Antonello, Cammarata, Silvia Miriam, Capone, Giacomo, Ianaro, Angela, Tenore, Gian Carlo, Pani, Luca, Novellino, Ettore

“…Currently, nutraceuticals do not have a specific definition distinct from those of other food‐derived categories, such as food supplements, herbal products,…”
Get full text

The therapeutic potential of apigenin by Salehi, Bahare, Venditti, Alessandro, Sharifi-Rad, Mehdi, Kregiel, Dorota, Sharifi-Rad, Javad, Durazzo, Alessandra, Lucarini, Massimo, Santini, Antonello, Souto, Eliana B., Novellino, Ettore, Antolak, Hubert, Azzini, Elena, Setzer, William N., Martins, Natália

“…Several plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic…”
Get full text

High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity by Russo Krauss, Irene, Merlino, Antonello, Randazzo, Antonio, Novellino, Ettore, Mazzarella, Lelio, Sica, Filomena

“…The G-quadruplex architecture is a peculiar structure adopted by guanine-rich oligonucleotidic sequences, and, in particular, by several aptamers, including…”
Get full text

Probiotic species in the modulation of the anticancer immune response by Marinelli, Luciana, Tenore, Gian Carlo, Novellino, Ettore

“…Mounting evidences are supporting a key role of distinct gut bacteria in the occurrence and progression of intestinal and extra-intestinal tumors. More…”
Get full text

Abelmoschus esculentus (L.): Bioactive Components' Beneficial Properties-Focused on Antidiabetic Role-For Sustainable Health Applications by Durazzo, Alessandra, Lucarini, Massimo, Novellino, Ettore, Souto, Eliana B, Daliu, Patricia, Santini, Antonello

“…The main features of the okra, (L.), are highlighted. The evaluation of interactions between biologically active compounds and other components of the food…”
Get full text

To Nutraceuticals and Back: Rethinking a Concept by Santini, Antonello, Novellino, Ettore

“…The concept of nutraceuticals as pharma-foods comes fromfar. This termismade fromthe two words "nutrient" and "pharmaceutical", was coined by Stephen DeFelice,…”
Get full text

Nutraceutical potential and antioxidant benefits of red pitaya (Hylocereus polyrhizus) extracts by Tenore, Gian Carlo, Novellino, Ettore, Basile, Adriana

“…Polyphenols from flesh and peels of red pitaya (Hylocereus polyrhizus) fruit were quantified by employing an extract sub-fractionation procedure applied for…”
Get full text

Topological Characterization of Nucleic Acid G-Quadruplexes by UV Absorption and Circular Dichroism by Karsisiotis, Andreas Ioannis, Hessari, Nason Ma'ani, Novellino, Ettore, Spada, Gian Piero, Randazzo, Antonio, Webba da Silva, Mateus

“…Four‐fold: Not just the identification, but also the rapid characterization and classification of nucleic acid G‐quadruplexes into topology groups is feasible…”
Get full text

In vitro bioaccessibility, bioavailability and plasma protein interaction of polyphenols from Annurca apple (M. pumila Miller cv Annurca) by Tenore, Gian Carlo, Campiglia, Pietro, Ritieni, Alberto, Novellino, Ettore

“…•Annurca apple polyphenols were subjected to in vitro gastrointestinal digestion.•The polyphenol bioaccessibility, bioavailability and protein binding were…”
Get full text

An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics by Durazzo, Alessandra, Nazhand, Amhirossein, Lucarini, Massimo, Atanasov, Atanas G., Souto, Eliana B., Novellino, Ettore, Capasso, Raffaele, Santini, Antonello

“…Over the last few years, the application of nanotechnology to nutraceuticals has been rapidly growing due to its ability to enhance the bioavailability of the…”
Get full text

Monohydrazone Based G‑Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells by Amato, Jussara, Miglietta, Giulia, Morigi, Rita, Iaccarino, Nunzia, Locatelli, Alessandra, Leoni, Alberto, Novellino, Ettore, Pagano, Bruno, Capranico, Giovanni, Randazzo, Antonio

“…Targeting G-quadruplex structures is currently viewed as a promising anticancer strategy. Searching for potent and selective G-quadruplex binders, here we…”
Get full text

Formation of [4Fe-4S] Clusters in the Mitochondrial Iron–Sulfur Cluster Assembly Machinery by Brancaccio, Diego, Gallo, Angelo, Mikolajczyk, Maciej, Zovo, Kairit, Palumaa, Peep, Novellino, Ettore, Piccioli, Mario, Ciofi-Baffoni, Simone, Banci, Lucia

“…The generation of [4Fe-4S] clusters in mitochondria critically depends, in both yeast and human cells, on two A-type ISC proteins (in mammals named ISCA1 and…”
Get full text

Colon Bioaccessibility and Antioxidant Activity of White, Green and Black Tea Polyphenols Extract after In Vitro Simulated Gastrointestinal Digestion by Annunziata, Giuseppe, Maisto, Maria, Schisano, Connie, Ciampaglia, Roberto, Daliu, Patricia, Narciso, Viviana, Tenore, Gian Carlo, Novellino, Ettore

“…The beneficial effects of the tea beverage are well-known and mainly attributed to polyphenols which, however, have poor bioaccessibility and bioavailability…”
Get full text

Effects of Grape Pomace Polyphenolic Extract (Taurisolo ® ) in Reducing TMAO Serum Levels in Humans: Preliminary Results from a Randomized, Placebo-Controlled, Cross-Over Study by Annunziata, Giuseppe, Maisto, Maria, Schisano, Connie, Ciampaglia, Roberto, Narciso, Viviana, Tenore, Gian Carlo, Novellino, Ettore

“…Trimethylamine N-oxide (TMAO) is considered a novel risk factor for cardiovascular diseases. Several studies demonstrated that polyphenols are able to inhibit…”
Get full text

HMGB1 binds to the KRAS promoter G-quadruplex: a new player in oncogene transcriptional regulation? by Amato, Jussara, Madanayake, Thushara W, Iaccarino, Nunzia, Novellino, Ettore, Randazzo, Antonio, Hurley, Laurence H, Pagano, Bruno

“…This communication reports on a possible distinct role of HMGB1 protein. Biophysical studies revealed that HMGB1 binds and stabilizes the G-quadruplex of the…”
Get more information

Dietary Lignans: Definition, Description and Research Trends in Databases Development by Durazzo, Alessandra, Lucarini, Massimo, Camilli, Emanuela, Marconi, Stefania, Gabrielli, Paolo, Lisciani, Silvia, Gambelli, Loretta, Aguzzi, Altero, Novellino, Ettore, Santini, Antonello, Turrini, Aida, Marletta, Luisa

“…The study aims to communicate the current status regarding the development and management of the databases on dietary lignans; within the phytochemicals, the…”
Get full text

Resveratrol as a Novel Anti-Herpes Simplex Virus Nutraceutical Agent: An Overview by Annunziata, Giuseppe, Maisto, Maria, Schisano, Connie, Ciampaglia, Roberto, Narciso, Viviana, Tenore, Gian Carlo, Novellino, Ettore

“…The herpes simplex virus (HSV) is a common human virus affecting many people worldwide. HSV infections manifest with lesions that occur in different parts of…”
Get full text

Anti-diabetic and anti-hyperlipidemic properties of Capparis spinosa L.: In vivo and in vitro evaluation of its nutraceutical potential by Mollica, Adriano, Zengin, Gokhan, Locatelli, Marcello, Stefanucci, Azzurra, Mocan, Andrei, Macedonio, Giorgia, Carradori, Simone, Onaolapo, Olakunle, Onaolapo, Adejoke, Adegoke, Juliet, Olaniyan, Marufat, Aktumsek, Abdurrahman, Novellino, Ettore

“…•Antidiabetic and antihyperlipidemic effects of Capparis spinosa from Lipari Island.•Extractions of buds, salty buds, leaf by different techniques.•HLPC-DAD…”
Get full text

Molecular basis of cyclooxygenase enzymes (COXs) selective inhibition by Limongelli, Vittorio, Bonomi, Massimiliano, Marinelli, Luciana, Gervasio, Francesco Luigi, Cavalli, Andrea, Novellino, Ettore, Parrinello, Michele

“…The widely used nonsteroidal anti-inflammatory drugs block the cyclooxygenase enzymes (COXs) and are clinically used for the treatment of inflammation, pain,…”
Get full text