Search Results - "Novelli, Lucia"
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Autoinflammatory and autoimmune conditions at the crossroad of COVID-19
Published in Journal of autoimmunity (01-11-2020)“…Coronavirus disease 2019 (COVID-19) has been categorized as evolving in overlapping phases. First, there is a viral phase that may well be asymptomatic or mild…”
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A case of psoriatic arthritis triggered by SARS-CoV-2 infection
Published in Rheumatology (Oxford, England) (05-01-2021)Get full text
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Autophagy and Rheumatoid Arthritis: Current Knowledges and Future Perspectives
Published in Frontiers in immunology (18-07-2018)“…Autophagy is a degradation mechanism by which cells recycle cytoplasmic components to generate energy. By influencing lymphocyte development, survival, and…”
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Pain in axial spondyloarthritis: role of the JAK/STAT pathway
Published in Frontiers in immunology (2024)“…Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that is characterized by new bone formation in the axial musculoskeletal system, with X-ray…”
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VDR Polymorphisms in Autoimmune Connective Tissue Diseases: Focus on Italian Population
Published in Journal of immunology research (23-12-2021)“…Vitamin D is an important hormone involved in various physiologic processes, and its activity is linked to binding with vitamin D receptor (VDR). Genetic…”
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TNFα expressed on the surface of microparticles modulates endothelial cell fate in rheumatoid arthritis
Published in Arthritis research & therapy (07-12-2018)“…Rheumatoid arthritis (RA) is associated with a high prevalence of atherosclerosis. Recently increased levels of microparticles (MPs) have been reported in…”
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Alteration of Mitochondrial DNA Copy Number and Increased Expression Levels of Mitochondrial Dynamics-Related Genes in Sjögren’s Syndrome
Published in Biomedicines (25-10-2022)“…Sjögren’s syndrome (SS) is a chronic autoimmune multifactorial disease characterized by inflammation and lymphocytic infiltration of the exocrine glands…”
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Extra-Articular Manifestations and Comorbidities in Psoriatic Disease: A Journey Into the Immunologic Crosstalk
Published in Frontiers in medicine (23-09-2021)“…Psoriatic arthritis (PsA) is a chronic inflammatory disease primarily affecting peripheral and axial joints, with the possible presence of extra-articular…”
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The JANUS of chronic inflammatory and autoimmune diseases onset during COVID-19 – A systematic review of the literature
Published in Journal of autoimmunity (01-02-2021)“…The diverse clinical manifestations of COVID-19 is emerging as a hallmark of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. While…”
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CYP4F2 genetic variant (rs2108622) significantly contributes to warfarin dosing variability in the Italian population
Published in Pharmacogenomics (01-02-2009)“…It is known that warfarin treatment is problematic, due to its narrow therapeutic range and to the great interindividual variability. Numerous papers have…”
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Immune checkpoint inhibitors-induced autoimmunity: The impact of gender
Published in Autoimmunity reviews (01-08-2020)“…To evaluate prevalence and clinical features of immune-related adverse events (irAEs) to immune checkpoint inhibitors (ICIs) in accordance with the gender of…”
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Effects of upadacitinib on enthesitis in patients with psoriatic arthritis: a post hoc analysis of SELECT-PsA 1 and 2 trials
Published in Rheumatology (Oxford, England) (01-11-2024)“…Abstract Objectives To characterize the effect of upadacitinib 15 mg once daily (UPA15) on enthesitis in patients with PsA from the SELECT-PsA Phase 3 trials…”
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The dysregulation of mitochondrial homeostasis-related genes could be involved in the decrease of mtDNA copy number in systemic lupus erythematosus patients
Published in Immunologic research (04-09-2024)“…Systemic lupus erythematosus (SLE) is a chronic multifactorial autoimmune disease. It is now widely demonstrated that oxidative stress (OS) plays an important…”
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A multilocus genetic study evidences the association of autoimmune-related genes with Psoriatic Arthritis in Italian patients
Published in Immunobiology (1979) (01-07-2022)“…Psoriatic Arthritis (PsA) is an immune-mediated rheumatic disease caused by the interaction between environmental factors and genetic predisposition. Many of…”
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A 2-year observational study on treatment targets in psoriatic arthritis patients treated with TNF inhibitors
Published in Clinical rheumatology (01-10-2017)“…The aim of this study was to evaluate clinical remission and MDA in PsA patients who started TNF-inhibitors (TNFi) treatment with a 2-year follow-up…”
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Large-scale DNA sequencing identifies rare variants associated with Systemic Lupus Erythematosus susceptibility in known risk genes
Published in Gene (20-05-2024)“…•Common genetic variants often have a modest effect on the SLE risk.•Rare variants in genes associated to SLE could have an effect on susceptibility.•Genomic…”
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Interaction between microbiome and host genetics in psoriatic arthritis
Published in Autoimmunity reviews (01-03-2018)“…Psoriatic arthritis (PsA) is a chronic inflammatory joint disease, seen in combination with psoriasis. Both genetic and environmental factors are responsible…”
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Emerging Role of microRNAs and Long Non-Coding RNAs in Sjögren’s Syndrome
Published in Genes (11-06-2021)“…Sjögren’s Syndrome (SS) is a chronic autoimmune inflammatory disease. It is considered a multifactorial pathology, in which underlying genetic predisposition,…”
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How Has Molecular Biology Enhanced Our Undertaking of axSpA and Its Management
Published in Current rheumatology reports (01-01-2023)“…Purpose This review aims at investigating pathophysiological mechanisms in spondyloarthritis (SpA). Analysis of genetic factors, immunological pathways, and…”
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KLRG1 is reduced on NK cells in SLE patients, inversely correlates with disease activity and is modulated by hydroxychloroquine in vitro
Published in Lupus (01-04-2023)“…Objectives Killer cell lectin-like receptor G 1 (KLRG1), a transmembrane receptor with inhibitory capacity expressed in human immune cells, emerged as a novel…”
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