Search Results - "Novak, K."

ERK1/2-mediated activation of DRP1 regulates mitochondrial dynamics and apoptosis in chondrocytes by Ansari, M.Y., Novak, K., Haqqi, T.M.

“…To determine the Dynamin-related protein 1 (DRP1) regulation of mitochondrial fission in chondrocytes under pathological conditions, an area which is…”
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Key ecological responses to nitrogen are altered by climate change by Greaver, T. L., Clark, C. M., Compton, J. E., Vallano, D., Talhelm, A. F., Weaver, C. P., Band, L. E., Baron, J. S., Davidson, E. A., Tague, C. L., Felker-Quinn, E., Lynch, J. A., Herrick, J. D., Liu, L., Goodale, C. L., Novak, K. J., Haeuber, R. A.

“…Climate change and anthropogenic nitrogen deposition are both important ecological threats. Evaluating their cumulative effects provides a more holistic view…”
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Novel ASAP1‐USP6, FAT1‐USP6, SAR1A‐USP6, and TNC‐USP6 fusions in primary aneurysmal bone cyst by Šekoranja, Daja, Zupan, Andrej, Mavčič, Blaž, Martinčič, David, Salapura, Vladka, Snoj, Žiga, Limpel Novak, Ana K., Pižem, Jože

“…Aneurysmal bone cyst (ABC) is a benign but locally aggressive neoplasm, with a tendency for local recurrence. In contrast to other bone tumors with secondary…”
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Different congenital hydrocephalus-associated mutations in Trim71 impair stem cell differentiation via distinct gain-of-function mechanisms by Liu, Qiuying, Novak, Mariah K, Pepin, Rachel M, Maschhoff, Katharine R, Hu, Wenqian

“…Congenital hydrocephalus (CH) is a common neurological disorder affecting many newborns. Imbalanced neurogenesis is a major cause of CH. Multiple CH-associated…”
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Repressing Ago2 mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs by Liu, Qiuying, Chen, Xiaoli, Novak, Mariah K, Zhang, Shaojie, Hu, Wenqian

“…The regulation of stem cell fate is poorly understood. Genetic studies in lead to the hypothesis that a conserved cytoplasmic double-negative feedback loop…”
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Clinical, endoscopic and radiographic outcomes with ustekinumab in medically‐refractory Crohn's disease: real world experience from a multicentre cohort by Ma, C., Fedorak, R. N., Kaplan, G. G., Dieleman, L. A., Devlin, S. M., Stern, N., Kroeker, K. I., Seow, C. H., Leung, Y., Novak, K. L., Halloran, B. P., Huang, V. W., Wong, K., Blustein, P. K., Ghosh, S., Panaccione, R.

“…Summary Background Ustekinumab is a monoclonal antibody targeting interleukins‐12 and ‐23, with efficacy in Crohn's disease (CD) demonstrated in clinical…”
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Lysosomal dysfunction in osteoarthritis and aged cartilage triggers apoptosis in chondrocytes through BAX mediated release of Cytochrome c by Ansari, M.Y., Ball, H.C., Wase, S.J., Novak, K., Haqqi, T.M.

“…Lysosomes are the major catabolic organelle of the cell and regulate the macromolecular and organelle turnover and programmed cell death. Here, we investigated…”
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Review article: dermatological complications of immunosuppressive and anti‐TNF therapy in inflammatory bowel disease by Moran, G. W., Lim, A. W. K., Bailey, J. L., Dubeau, M.‐F., Leung, Y., Devlin, S. M., Novak, K., Kaplan, G. G., Iacucci, M., Seow, C., Martin, L., Panaccione, R., Ghosh, S.

“…Summary Background With the expanding list of medications available to treat patients with inflammatory bowel disease (IBD), it is important to recognise…”
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Quantum interference phenomena and electron – electron interaction in topological insulator Bi2Se3 thin polycrystalline films by Rogacheva, E.I., Pavlosiuk, O., Meriuts, A.V., Shelest, T.N., Sipatov, A.Yu, Nashchekina, O.N., Novak, K.V., Kaczorowski, D.

“…•We studied the transport properties of 40 and 200 nm polycrystalline Bi2Se3 films.•We observed “transport paradox” in their magnetic field and temperature…”
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Structure-based constitutive model can accurately predict planar biaxial properties of aortic wall tissue by Polzer, S., Gasser, T.C., Novak, K., Man, V., Tichy, M., Skacel, P., Bursa, J.

“…[Display omitted] Structure-based constitutive models might help in exploring mechanisms by which arterial wall histology is linked to wall mechanics. This…”
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microRNA-mediated regulation of microRNA machinery controls cell fate decisions by Liu, Qiuying, Novak, Mariah K, Pepin, Rachel M, Eich, Taylor, Hu, Wenqian

“…microRNAs associate with Argonaute proteins, forming the microRNA-induced silencing complex (miRISC), to repress target gene expression post-transcriptionally…”
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Towards Routine Non-invasive Monitoring of Disease Activity Using Gastrointestinal Ultrasound and Faecal Calprotectin in Pregnant Women With IBD by Seow, C H, Leung, Y, Novak, K L

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Cognitive performance of GBA mutation carriers with early-onset PD: The CORE-PD study by ALCALAY, R. N, CACCAPPOLO, E, LOUIS, E, COMELLA, C, COLCHER, A, JENNINGS, D, NANCE, M, BRESSMAN, S, SCOTT, W. K, TANNER, C, MICKEL, S, ANDREWS, H, MEJIA-SANTANA, H, WATERS, C, FAHN, S, COTE, L, FRUCHT, S, FORD, B, REZAK, M, NOVAK, K, FRIEDMAN, J. H, PFEIFFER, R, MARSH, L, TANG, M.-X, HINER, B, SIDEROWF, A, PAYAMI, H, MOLHO, E, FACTOR, S, OTTMAN, R, CLARK, L. N, MARDER, K, ROSADO, L, ORBE REILLY, M, RUIZ, D, ROSS, B, VERBITSKY, M, KISSELEV, S

“…To assess the cognitive phenotype of glucocerebrosidase (GBA) mutation carriers with early-onset Parkinson disease (PD). We administered a neuropsychological…”
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Reduction in surgical stoma rates in Crohn's disease: a population‐based time trend analysis by Ma, C., Almutairdi, A., Tanyingoh, D., Seow, C. H., Novak, K. L., Lu, C., Panaccione, R., Kaplan, G. G., Kotze, P. G.

“…Aim Trends in surgical rates for Crohn's disease (CD) in the biological era are controversial. We aim to assess modern trends in the formation rates of…”
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Oral Epithelial Cell Responses to Multispecies Microbial Biofilms by Peyyala, R., Kirakodu, S.S., Novak, K.F., Ebersole, J.L

“…This report describes the use of a novel model of multispecies biofilms to stimulate profiles of cytokines/chemokines from oral epithelial cells that…”
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C0335: Median Arcuate Ligement Syndrome and Thrombophilia: Case Report by Glavas, D, Novak, K

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The use of overlapping submovements in the control of rapid hand movements by NOVAK, K. E, MILLER, L. E, HOUK, J. C

“…Rapid targeted movements are subject to special control considerations, since there may be inadequate time available for either visual or somatosensory…”
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Slc7a11 Gene Controls Production of Pheomelanin Pigment and Proliferation of Cultured Cells by Chintala, Sreenivasulu, Li, Wei, Lamoreux, M. Lynn, Ito, Shosuke, Wakamatsu, Kazumasa, Sviderskaya, Elena V., Bennett, Dorothy C., Park, Young-Mee, Gahl, William A., Huizing, Marjan, Spritz, Richard A., Ben, Songtao, Novak, Edward K., Tan, Jian, Swank, Richard T., Sly, William S.

“…In mammals, > 100 genes regulate pigmentation by means of a wide variety of developmental, cellular, and enzymatic mechanisms. Nevertheless, genes that…”
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BLOOD PRESSURE PROFILE, CATECHOLAMINE PHENOTYPE AND TARGET ORGAN DAMAGE IN PHEOCHROMOCYTOMA/PARAGANGLIOMA by Petrak, O, Rosa, J, Holaj, R, Strauch, B, Kratka, Z, Kvasnicka, J, Klimova, J, Waldauf, P, Hamplova, B, Markvartova, A, Novak, K, Michalsky, D, Widimsky, J, Zelinka, T

“…OBJECTIVE:Impaired diurnal blood pressure (BP) variability is related to higher cardiovascular risk. The aim of the study was to assess diurnal variability of…”
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Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1) by Swank, Richard T, Li, Wei, Zhang, Qing, Oiso, Naoki, Novak, Edward K, Gautam, Rashi, O'Brien, Edward P, Tinsley, Caroline L, Blake, Derek J, Spritz, Richard A, Copeland, Neal G, Jenkins, Nancy A, Amato, Dominick, Roe, Bruce A, Starcevic, Marta, Dell'Angelica, Esteban C, Elliott, Rosemary W, Mishra, Vishnu, Kingsmore, Stephen F, Paylor, Richard E

“…Hermansky-Pudlak syndrome (HPS; MIM 203300) is a genetically heterogeneous disorder characterized by oculocutaneous albinism, prolonged bleeding and pulmonary…”
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