Search Results - "Novak, Josef F."

Proenzyme Therapy of Cancer by NOVAK, Josef F, TRNKA, Frantisek

“…Proteases and their inhibitors have long been investigated in numerous tumor systems, and at the tumor growing front, their balance has been universally found…”
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Constitutive and ligand‐induced nuclear localization of oxytocin receptor by Kinsey, Conan G., Bussolati, Gianni, Bosco, Martino, Kimura, Tadashi, Pizzorno, Marie C., Chernin, Mitchell I., Cassoni, Paola, Novak, Josef F.

“…Oxytocin receptor (OTR) is a membrane protein known to mediate oxytocin (OT) effects, in both normal and neoplastic cells. We report here that human…”
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Differential Effects of Serine Proteases on the Migration of Normal and Tumor Cells: Implications for Tumor Microenvironment by Elzer, Kirsten L., Heitzman, Deborah A., Chernin, Mitchell I., Novak, Josef F.

“…The supporting role of proteases in tumor progression and invasion is well known; however, the use of proteases as therapeutic agents has also been…”
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Transformation of MC3T3-E1 cells following stress and transfection with pSV2neo plasmid by Takahashi, Mitsugu, Chernin, Mitchell I, Yamamoto, Osamu, Tonzetich, John, Kinsey, Conan G, Novak, Josef F

“…A continuous cell line, MC3T3-E1 cells, originally derived from murine calvaria bones, loses its osteogenic properties as a result of extended passage number…”
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Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex by Campbell, P G, Novak, J F, Yanosick, T B, McMaster, J H

“…A variety of treatments, including acid, heparin, and proteases, are known to free insulin-like growth factors (IGFs) from their binding proteins (IGFBPs)…”
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Insulin-like growth factor binding protein (IGFBP) inhibits IGF action on human osteosarcoma cells by Campbell, P G, Novak, J F

“…The influence of a human insulin-like growth factor binding protein, hIGFBP-1, on the action of IGFs on human osteosarcoma cells was examined. hIGFBP-1 was…”
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Binding and activation of plasminogen on the surface of osteosarcoma cells by Campbell, P G, Wines, K, Yanosick, T B, Novak, J F

“…Plasmin (Pm) is a broad action serine protease implicated in numerous physiological functions. In bone, Pm may play a role in growth, resorption, metastasis,…”
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BIOCHEMICAL STUDIES ON NORMAL AND TUMOROUS TISSUES OF PHASEOLUS VULGARIS HYPOCOTYL by NOVAK, JOSEF F

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Resistance to pyrazofurin and 6-azauridine in normal MC3T3-E1 murine osteoblasts by Beidler, D R, Candia, A F, Chernin, M I, Novak, J F

“…Stable variants resistant to pyrazofurin (PF) and 6-azauridine (AZUrd) were serially selected in increasing drug concentrations from an MC3T3-E1 nontumorigenic…”
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Effect of 6-azauridine and pyrazofurin on fibrinolysis by L1210 leukemic cells by Novak, J F

“…The expression of plasminogen activator activity (PA) by L1210 leukemic ascitic cells, obtained from the peritoneum of BDF1 mice, increases in the terminal…”
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Bone resorption in osteogenic sarcoma. I. Release of calcium by tumor cells, normal fibroblasts, and macrophages by Fukushima, H, Novak, J F, McMaster, J H, Asanuma, K, Yong, M C

“…The bone calcium resorption activities of three different types of cells that are present either within or in the vicinity of an osteogenic sarcoma tumor mass…”
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Bone resorption in osteogenic sarcoma--II. Resorption of the bone collagenous matrix by tumor cells, normal fibroblasts and macrophages by Novak, J F, Fukushima, H, McMaster, J H, Asanuma, K, Simpson, K A

“…Three osteogenic sarcoma cell lines of human and canine origin were compared to normal fibroblastic cells and peptone-induced murine peritoneal macrophages in…”
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