Search Results - "Novaira, Horacio J"

Glucagon Regulates Hepatic Kisspeptin to Impair Insulin Secretion by Song, Woo-Jin, Mondal, Prosenjit, Wolfe, Andrew, Alonso, Laura C., Stamateris, Rachel, Ong, Benny W.T., Lim, Owen C., Yang, Kil S., Radovick, Sally, Novaira, Horacio J., Farber, Emily A., Farber, Charles R., Turner, Stephen D., Hussain, Mehboob A.

“…Early in the pathogenesis of type 2 diabetes mellitus (T2DM), dysregulated glucagon secretion from pancreatic α cells occurs prior to impaired…”
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Disrupted Kisspeptin Signaling in GnRH Neurons Leads to Hypogonadotrophic Hypogonadism by Novaira, Horacio J, Sonko, Momodou L, Hoffman, Gloria, Koo, Yongbum, Ko, Chemyong, Wolfe, Andrew, Radovick, Sally

“…Landmark studies have shown that mutations in kisspeptin and the kisspeptin receptor (Kiss1r) result in reproductive dysfunction in humans and genetically…”
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Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines by Novaira, Horacio J., Ng, Yewade, Wolfe, Andrew, Radovick, Sally

“…Kisspeptins, and their G-protein coupled receptor 54 (GPR54), are key components in the regulation of gonadotropin-releasing hormone (GnRH) secretion in humans…”
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Genetic mechanisms mediating kisspeptin regulation of GnRH gene expression by Novaira, Horacio J, Fadoju, Doris, Diaczok, Daniel, Radovick, Sally

“…Kisspeptins (Kiss) have been shown to be key components in the regulation of gonadotropin-releasing hormone (GnRH) secretion. In vitro studies have…”
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Both Estrogen Receptor α and β Stimulate Pituitary GH Gene Expression by Avtanski, Dimiter, Novaira, Horacio J, Wu, Sheng, Romero, Christopher J, Kineman, Rhonda, Luque, Raul M, Wondisford, Fredric, Radovick, Sally

“…Although sex steroids have been implicated in the control of mammalian growth, their direct effect on GH synthesis is less clear. The aim of this study was to…”
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Impairments in the reproductive axis of female mice lacking estrogen receptor β in GnRH neurons by Novaira, Horacio J, Negron, Ariel L, Graceli, Jones B, Capellino, Silvia, Schoeffield, Andrew, Hoffman, Gloria E, Levine, Jon E, Wolfe, Andrew, Wondisford, Fredric E, Radovick, Sally

“…The effect of estrogen on the differentiation and maintenance of reproductive tissues is mediated by two nuclear estrogen receptors (ERs), ERα, and ERβ. Lack…”
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Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E by McManus, Duneia, Novaira, Horacio J, Hamers, Anouk A J, Pillai, Asha B

“…The intestine is the home to the largest number of immune cells in the body. The small and large intestinal immune systems police exposure to exogenous…”
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The gonadotropin-releasing hormone cell-specific element is required for normal puberty and estrous cyclicity by Novaira, Horacio J, Yates, Melissa, Diaczok, Daniel, Kim, Helen, Wolfe, Andrew, Radovick, Sally

“…Appropriate tissue-specific gene expression of gonadotropin-releasing hormone (GnRH) is critical for pubertal development and maintenance of reproductive…”
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Estrogen regulation of gene expression in GnRH neurons by Ng, Yewade, Wolfe, Andrew, Novaira, Horacio J., Radovick, Sally

“…Estrogen plays an essential role in the regulation of the female reproductive hormone axis, and specifically is a major regulator of GnRH neuronal function in…”
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Development and Characterization of Novel Rat Anti-mERβ Sera by Novaira, Horacio J, Graceli, J. B, Capellino, S, Schoeffield, A, Hoffman, G. E, Wolfe, A, Wondisford, F, Radovick, S

“…Estrogens regulate normal sexual and reproductive development in females. Their actions are mediated mainly by estrogen receptor (ER)α and ERβ. Understanding…”
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Thyroid Hormones Stimulate Renal Expression of CFTR by de Andrade Pinto, Ana C.O., Barbosa, Carolina M.L., Ornellas, Debora S., Novaira, Horacio J., de Souza-Menezes, Jackson, Ortiga-Carvalho, Tania M., Fong, Peying, Morales, Marcelo M.

“…CFTR is a multifunctional protein of the ATP binding cassette family that may contribute to overall electrolyte homeostasis by acting as a chloride channel in…”
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Modulation of renal CNG-A3 sodium channel in rats subjected to low- and high-sodium diets by Novaira, Horacio J., Botelho, Bruno F., Goldenberg, Regina C., Guggino, Sandra E., Morales, Marcelo M.

“…In this work, we studied the mRNA distribution of CNG-A3, an amiloride-sensitive sodium channel that belongs to the cyclic nucleotide-gated (CNG) family of…”
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Development and Characterization of Novel Rat Anti-mER[beta] Sera by Novaira, Horacio J, Graceli, J B, Capellino, S, Schoeffield, A, Hoffman, G E, Wolfe, A, Wondisford, F, Radovick, S

“…Estrogens regulate normal sexual and reproductive development in females. Their actions are mediated mainly by estrogen receptor (ER)[alpha] and ER[beta]…”
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