Search Results - "Novack, Vance J"

General Strategies toward the Syntheses of Macrolide Antibiotics. The Total Syntheses of 6-Deoxyerythronolide B and Oleandolide by Evans, David A, Kim, Annette S, Metternich, Rainer, Novack, Vance J

“…The asymmetric syntheses of 6-deoxyerythronolide B (1) and oleandolide (2) have been achieved, each in 18 linear steps. These syntheses demonstrate the utility…”
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A practical, enantioselective synthesis of SK&F 104353 by Flisak, Joseph R, Gombatz, Kerry J, Holmes, Monica M, Jarmas, Alvydas A, Lantos, Ivan, Mendelson, Wilford L, Novack, Vance J, Remich, James J, Snyder, Lawrence

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Diastereoselective aldol reactions using .beta.-keto imide derived enolates. A versatile approach to the assemblage of polypropionate systems by Evans, David A, Clark, J. Stephen, Metternich, Rainer, Novack, Vance J, Sheppard, George S

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Rearrangement of Epoxynitriles:  A Convenient Homologation of Acyclic and Cyclic Ketones to Carboxylic Acids by Badham, Neil F, Mendelson, Wilford L, Allen, Andrew, Diederich, Ann M, Eggleston, Drake S, Filan, John J, Freyer, Alan J, Killmer, Lewis B, Kowalski, Conrad J, Liu, Li, Novack, Vance J, Vogt, Frederick G, Webb, Kevin S, Yang, Jennifer

“…A convenient two-step homologation of both aliphatic and aromatic ketones to the corresponding carboxylic acid has been developed. First ketones were converted…”
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A highly stereoselective synthesis of transepoxides via arsonium ylides by Still, W. Clark, Novack, Vance J

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A Practical Synthesis of the PDE4 Inhibitor, SB-207499, from a Cyclohexanone Precursor by Badham, Neil F, Chen, Jian-Hao, Cummings, Paul G, Dell'Orco, Philip C, Diederich, Ann M, Eldridge, Ann M, Mendelson, Wilford L, Mills, Robert J, Novack, Vance J, Olsen, Mark A, Rustum, Abu M, Webb, Kevin S, Yang, Shawn

“…The synthesis of SB-207499 is described. Investigation and development of new strategies for the homologation of ketone,…”
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Macrocyclic stereocontrol. Total synthesis of (.+-.)-3-deoxyrosaranolide by Still, W. Clark, Novack, Vance

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A Direct and High Yielding Route to 2-(5-Tetrazolyl) Substituted Benzopyran-4-ones: Synthesis of Pranlukast by Geen, Graham R., Giles, Robert G., Grinter, Trevor J., Hayler, John D., Howie, Simon L. B., Johnson, Graham, Mann, Inderjit S., Novack, Vance J., Oxley, Paul W., Quick, John K., Smith, Neil

“…A direct and high yielding route to 2-(5-tetrazolyl)benzopyran-4-ones 1, including pranlukast 1a is described. This involves the Claisen condensation reaction…”
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