Search Results - "Nour El‑Din, Hanzada T."
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PLGA and PDMS-based in situ forming implants loaded with rosuvastatin and copper-selenium nanoparticles: a promising dual-effect formulation with augmented antimicrobial and cytotoxic activity in breast cancer cells
Published in Frontiers in pharmacology (04-06-2024)“…Breast cancer is among the most prevalent tumors worldwide. In this study, forming implants (ISFIs) containing rosuvastatin calcium were prepared using three…”
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A Rapid Lysostaphin Production Approach and a Convenient Novel Lysostaphin Loaded Nano-emulgel; As a Sustainable Low-Cost Methicillin-Resistant Staphylococcus aureus Combating Platform
Published in Biomolecules (Basel, Switzerland) (12-03-2020)“…is a Gram-positive pathogen that is capable of infecting almost every organ in the human body. Alarmingly, the rapid emergence of methicillin-resistant strains…”
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Genome-Scale Investigation of the Regulation of azoR Expression in Escherichia coli Using Computational Analysis and Transposon Mutagenesis
Published in Microbial ecology (01-12-2024)“…Bacterial azoreductases are enzymes that catalyze the reduction of ingested or industrial azo dyes. Although azoreductase genes have been well identified and…”
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Exploring the structure-activity relationships of diphenylurea as an antibacterial scaffold active against methicillin- and vancomycin-resistant Staphylococcus aureus
Published in European journal of medicinal chemistry (15-04-2022)“…A set of structurally related diphenylurea derivatives bearing aminoguanidine moiety were synthesized, and their antibacterial activity was assessed against a…”
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Novel PhoH-encoding vibriophages with lytic activity against environmental Vibrio strains
Published in Archives of microbiology (01-11-2021)“…Cholera is a devastating diarrheal disease that accounts for more than 10% of children’s lives worldwide, but its treatment is hampered by a rise in antibiotic…”
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Microbial evasion of the complement system: a continuous and evolving story
Published in Frontiers in immunology (04-01-2024)“…The complement system is a fundamental part of the innate immune system that plays a key role in the battle of the human body against invading pathogens…”
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Exploring novel aryl/heteroaryl-isosteres of phenylthiazole against multidrug-resistant bacteria
Published in RSC advances (29-06-2023)“…Antimicrobial resistance has become a concern as a worldwide threat. A novel scaffold of phenylthiazoles was recently evaluated against multidrug-resistant…”
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Phenotypic characterization of phage vB_vcM_Kuja
Published in Journal of basic microbiology (01-05-2023)“…Bacteriophage therapy targeting the increasingly resistant Vibrio cholerae is highly needed. Hence, studying the phenotypic behavior of potential phages under…”
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Expanding the structure-activity relationships of alkynyl diphenylurea scaffold as promising antibacterial agents
Published in RSC medicinal chemistry (22-02-2023)“…With the continuous and alarming threat of exhausting the current antimicrobial arsenals, efforts are urgently needed to develop new effective ones. In this…”
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Phenotype-Genotype Characterization and Antibiotic-Resistance Correlations Among Colonizing and Infectious Methicillin-Resistant Staphylococcus aureus Recovered from Intensive Care Units
Published in Infection and drug resistance (01-01-2021)“…Methicillin-resistant (MRSA) presents a profound hazard to public health. MRSA colonizing skin, mucous membranes, and the anterior nares without clinical…”
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Nanobodies in the fight against infectious diseases: repurposing nature's tiny weapons
Published in World journal of microbiology & biotechnology (01-07-2024)“…Nanobodies are the smallest known antigen-binding molecules to date. Their small size, good tissue penetration, high stability and solubility, ease of…”
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