Search Results - "Nour, E."
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Design, Green Synthesis and Tailoring of Vitamin E TPGS Augmented Niosomal Nano-Carrier of Pyrazolopyrimidines as Potential Anti-Liver and Breast Cancer Agents with Accentuated Oral Bioavailability
Published in Pharmaceuticals (Basel, Switzerland) (09-03-2022)“…VEGF plays a crucial role in cancer development, angiogenesis and progression, principally liver and breast cancer. It is vital to uncover novel chemical…”
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2
Design and Synthesis of New CDK2 Inhibitors Containing Thiazolone and Thiazolthione Scafold with Apoptotic Activity
Published in Chemical & pharmaceutical bulletin (01-01-2021)“…Cyclin dependent kinase 2 (CDK2) inhibition is a well-established strategy for treating cancer. Different series of novel thiazolone (1, 7–9) together with…”
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3
Magnetic Reconnection as the Driver of the Solar Wind
Published in The Astrophysical journal (01-03-2023)“…We present EUV solar observations showing evidence for omnipresent jetting activity driven by small-scale magnetic reconnection at the base of the solar…”
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4
Radiation Synthesis of Rapidly Self‐Healing Hydrogel Derived from Poly(acrylic acid) with Good Mechanical Strength
Published in Macromolecular chemistry and physics (01-10-2020)“…This article aims at designing a new self‐healing hydrogel with good mechanical strength. A new class of carbamothioyl monomer of…”
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5
First Direct Imaging of a Kelvin–Helmholtz Instability by PSP/WISPR
Published in The Astrophysical journal (01-04-2024)“…Abstract We present a comprehensive analysis aimed at proving the hypothesis that a train of small-scale features observed by the Wide-field Imager (WISPR)…”
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6
Preparation of thiourea derivative incorporated Ag3PO4 core shell for enhancement of photocatalytic degradation performance of organic dye under visible radiation light
Published in Scientific reports (03-06-2024)“…Photocatalysis is a promising technique to reduce hazardous organic pollutants using semiconductors under visible light. However, previous studies have been…”
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Discovery of pyrano[2,3-]pyrimidine-2,4-dione derivatives as novel PARP-1 inhibitors: design, synthesis and antitumor activity
Published in RSC advances (22-01-2021)“…Poly(ADP-ribose) polymerases-1 (PARP-1) are involved in DNA repair damage and so PARP-1 inhibitors have been used as potentiators in combination with DNA…”
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8
The Pattern of Acetylation Defines the Priming Activity of Chitosan Tetramers
Published in Journal of the American Chemical Society (29-01-2020)“…The biological activity of chitosans depends on their degree of polymerization (DP) and degree of acetylation (DA). However, information could also be carried…”
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9
β‐Lactam Synthesis through Diodomethane Addition to Amide Dianions
Published in Angewandte Chemie International Edition (25-09-2017)“…We present a novel route for the quick and easy synthesis of a broad range of β‐lactams. The synthesis involves a [3+1] cyclization of amide dianions with…”
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10
Heavy metals contamination in seawater, sediments and seashells of the Gulf of Suez, Egypt
Published in Environmental earth sciences (01-06-2020)“…A comprehensive environmental assessment of the Abu Zenima coast, Egypt, was done by evaluating the heavy metal pollutant levels in sediments, marine…”
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11
Parker Solar Probe Enters the Magnetically Dominated Solar Corona
Published in Physical review letters (17-12-2021)“…The high temperatures and strong magnetic fields of the solar corona form streams of solar wind that expand through the Solar System into interstellar space…”
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12
Influence of quality labels on the formation of preferences of lamb meat consumers. A Spanish case study
Published in Meat science (01-01-2018)“…Analysis of the attributes determining the formation of consumers' preferences when buying lamb meat is a key aspect in increasing the demand for this product…”
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13
New Evidence on the Origin of Solar Wind Microstreams/Switchbacks
Published in Astrophysical journal. Letters (01-07-2023)“…Abstract Microstreams are fluctuations in the solar wind speed and density associated with polarity-reversing folds in the magnetic field (also denoted…”
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14
Quasi-periodic Energy Release and Jets at the Base of Solar Coronal Plumes
Published in The Astrophysical journal (01-07-2022)“…Coronal plumes are long, ray-like, open structures that have been considered as possible sources of the solar wind. Their origin in the largely unipolar…”
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15
Design, Molecular Docking, Synthesis, Anticancer and Anti-Hyperglycemic Assessments of Thiazolidine-2,4-diones Bearing Sulfonylthiourea Moieties as Potent VEGFR-2 Inhibitors and PPARγ Agonists
Published in Pharmaceuticals (Basel, Switzerland) (14-02-2022)“…Newly designed thiazolidine-2,4-diones - - were synthesized, and their anticancer activities were screened against three cancer lines. They showed potent…”
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16
Novel 4-thiophenyl-pyrazole, pyridine, and pyrimidine derivatives as potential antitumor candidates targeting both EGFR and VEGFR-2; design, synthesis, biological evaluations, and in silico studies
Published in RSC advances (17-04-2023)“…In this article, we continued our previous effort to develop new selective anticancer candidates based on the basic pharmacophoric requirements of both EGFR…”
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17
Female sexual behavior is disrupted in a preclinical mouse model of PCOS via an attenuated hypothalamic nitric oxide pathway
Published in Proceedings of the National Academy of Sciences - PNAS (26-07-2022)“…Women with polycystic ovary syndrome (PCOS) frequently experience decreased sexual arousal, desire, and sexual satisfaction. While the hypothalamus is known to…”
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18
Self-similar Outflows at the Source of the Fast Solar Wind: A Smoking Gun of Multiscale Impulsive Reconnection?
Published in Astrophysical journal. Letters (01-10-2023)“…We present results of a quantitative analysis of structured plasma outflows above a polar coronal hole observed by the Atmospheric Imaging Assembly (AIA) on…”
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19
Ion Kinetics of Plasma Interchange Reconnection in the Lower Solar Corona
Published in The Astrophysical journal (01-12-2023)“…Abstract The exploration of the inner heliosphere by the Parker Solar Probe has revealed a highly structured solar wind with ubiquitous deflections from the…”
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20
On the Heating of the Slow Solar Wind by Imbalanced Alfvén-wave Turbulence from 0.06 to 1 au: Parker Solar Probe and Solar Orbiter Observations
Published in Astrophysical journal. Letters (01-06-2024)“…Abstract In this work we analyze plasma and magnetic field data provided by the Parker Solar Probe and Solar Orbiter missions to investigate the radial…”
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